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科研机构
湖南中医药大学 [9]
内容类型
期刊论文 [9]
发表日期
2016 [3]
2014 [3]
2013 [1]
2011 [1]
2010 [1]
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专题:湖南中医药大学
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The anti-dementia drug candidate, (-)-clausenamide, improves memory impairment through its multi-target effect
期刊论文
Pharmacology and Therapeutics, 2016, 卷号: 162, 页码: 179-187
作者:
Chu, Shifeng
;
Liu, Shaolin
;
Duan, Wenzhen
;
Cheng, Yong
;
Jiang, Xueying
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
Chirality
Clausenamide
Dementia
Long-term potentiation
Signaling pathway
Calcium
6-OHDA
6-hydroxyldopamine
ACE
acetylcholinesterase
ACh
acetylcholine
AD
Alzheimer's disease
AUC0–12 h
0–12 h area under curve
APP
amyloid precursor protein
APV
R-2-amino-5-phosphonopentanoate
AUC0−∝
whole area under curve
BBB
blood–brain barrier
BDNF
brain-derived neurotrophic factor
CaM
calmodulin
CaMKII
calmodulin kinase II
ChAT
choline acetyltransferase
CREB
cAMP responding element binding
CHM
Chinese herbal medicine
clau
clausenamide
CL
clearance
Cmax
maximum concentration
CDK-5
cyclin-dependent kinase-5
DM
diabetes mellitus
DAG
diacylglycerol
ER
endoplasmic reticulum
ERK
extracellular signal-regulated kinases
GSK-3
glycogen synthase kinase-3
IP3
inositol triphosphate
LTP
long term potentiation
MWM
Morris water maze
NGF
nerve growth factor
NMDA
N-Methyl-D-aspartate
D
nNOS
neural nitric oxide synthase
PAT
passive avoidance tasks
Pir
piracetam
PLC
phospholipase C
PP1
phosphate 1
PKC
protein kinase C
tmax
time of peak concentration
t1/2α
absorption half-life
t1/2β
elimination half-life
Tau
microtubule-associated proteins
TCM
traditional Chinese medicine
Vd
apparent volume of distribution
VDCC
voltage-dependent calcium channel
The Potential Biomarkers to Identify the Development of Steatosis in Hyperuricemia
期刊论文
PLOS ONE, 2016, 卷号: 11, 期号: 2, 页码: e0149043
作者:
Tan, Yong
;
Liu, Xinru
;
Zhou, Ke
;
He, Xiaojuan
;
Lu, Cheng
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/27
Metabolic pathways,Purine metabolism,Metabolites,Metabolic networks,Enzyme metabolism,Inosine,Phospholipases,Uric acid
Central neuromechanisms underlying control of intragastric pressure through acupuncture at Zusanli (ST36) in rats: the upper cervical cord is the key link between the ascending and descending pathways
期刊论文
Neural Regeneration Research, 2016, 卷号: 11, 期号: 6, 页码: 971-976
作者:
Yong, Chun-yan
;
Chen, Shu
;
Chen, Heng
;
Chu, Xiao
;
Zhang, Chao
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/27
Zusanli (ST36)
acupuncture
dorsal cord
dorsolateral funiculus
hypothalamic paraventricular nucleus
immunohistochemical double staining
intragastric pressure
nerve regeneration
nervous pathway
neural regeneration
traditional Chinese medicine
upper cervical cord
Metabolic profiling reveals therapeutic biomarkers of processed Aconitum Carmichaeli Debx in treating hydrocortisone induced Kidney-Yang deficiency syndrome rats
期刊论文
Journal of Ethnopharmacology, 2014, 卷号: 152, 期号: 3, 页码: 585-593
作者:
Tan, Yong
;
Liu, Xinru
;
Lu, Cheng
;
He, Xiaojuan
;
Li, Jian
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
TCM
traditional Chinese medicine
KYDS
Kidney-Yang Deficiency syndrome
HPLC
high-performance liquid chromatography
LC/MS
high-pressure liquid chromatography combined mass spectrometry
LC-Q-TOF-MS
liquid chromatography quadruple time-of-flight mass spectrometry
EIC
extracted ion chromatograms
ESI
electrospray ionization
PCA
principal components analysis
PLS-DA
partial-least-squares discriminate analysis
OPLS
orthogonal partial least square
IPA
ingenuity pathway analysis
cAMP
cyclic adenosine monophosphate
cGMP
cyclic guanosine monophosphate
ACTH
adrenocorticotrophic hormone
CHM
Chinese herbal medicines
Metabolic profiling
Processed Aconitum carmichaeli debx
Therapeutic biomarkers
Kidney-Yang deficiency syndrome rats
MiRNA-15a mediates cell cycle arrest and potentiates apoptosis in breast cancer cells by targeting synuclein-gamma.
期刊论文
Asian Pacific journal of cancer prevention : APJCP, 2014, 卷号: 15, 期号: 16, 页码: 6949-6954
作者:
Li, Ping
;
Xie, Xiao-Bing
;
Chen, Qian
;
Pang, Guo-Lian
;
Luo, Wan
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/27
microRNA-15a
breast cancer
SNCG
cell cycle
apoptosis
Metal-free synthesis of oxindoles via (NH4)2S2O8-mediated halocarbocyclization of alkenes in water
期刊论文
Journal of Organic Chemistry, 2014, 卷号: 79, 期号: 22, 页码: 10829-10836
作者:
Zhang, Ming-Zhong
;
Sheng, Wen-Bing
;
Jiang, Qing
;
Tian, Mi
;
Yin, Yong
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/27
Anthraquinone derivatives from Rumex plants and endophytic Aspergillus fumigatus and their effects on diabetic nephropathy
期刊论文
Bioorganic and Medicinal Chemistry Letters, 2013, 卷号: 23, 期号: 13, 页码: 3905-3909
作者:
Yang, Yang
;
Yan, Yong-Ming
;
Wei, Wei
;
Luo, Jie
;
Zhang, Lan-Sheng
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/27
Anthraquinone
Aspergillus fumigatus
C-glycoside
Diabetic nephropathy
Endophytic
Oxanthrone
Rumex
Sesquiterpene and Norsesquiterpene Derivatives from Sanicula lamelligera and Their Biological Evaluation
期刊论文
Journal of natural products, 2011, 卷号: 74, 期号: 6, 页码: 1521-1525
作者:
Li, Xue-Song
;
Zhou, Xiao-Jiang
;
Zhang, Xing-Jie
;
Su, Jia
;
Li, Xue-Jing
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/27
Antioxidant phenolics from Broussonetia papyrifera fruits
期刊论文
Journal of Asian natural products research, 2010, 卷号: 12, 期号: 5, 页码: 399-406
作者:
Zhou, Xiao-Jiang
;
Mei, Ren-Qiang
;
Zhang, Li
;
Lu, Qing
;
Zhao, Jun
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/27
Antioxidation
Broussonetia papyrifera
Phenolics
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