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GADD45 beta stabilized by direct interaction with HSP72 ameliorates insulin resistance and lipid accumulation 期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 173, 页码: 11
作者:  Dong, Yunxia;  Ma, Ningning;  Fan, Lei;  Yuan, Luyang;  Wu, Qian
收藏  |  浏览/下载:61/0  |  提交时间:2021/12/16
Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090
作者:  Jin, Tingting;  Xu, Lei;  Wang, Peipei;  Hu, Xiaobei;  Zhang, Runyuan
收藏  |  浏览/下载:23/0  |  提交时间:2022/01/04
Solidification of volatile D-Limonene by cyclodextrin metal-organic framework for pulmonary delivery via dry powder inhalers: In vitro and in vivo evaluation 期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2021, 卷号: 606, 页码: 9
作者:  Zhou, Yong;  Zhang, Meijuan;  Wang, Caifen;  Ren, Xiaohong;  Guo, Tao
收藏  |  浏览/下载:120/0  |  提交时间:2021/11/04
Allicin inclusions with alpha-cyclodextrin effectively masking its odor: Preparation, characterization, and olfactory and gustatory evaluation 期刊论文
JOURNAL OF FOOD SCIENCE, 2021, 页码: 11
作者:  Zhou, Yong;  Feng, Jing;  Peng, Hui;  Guo, Tao;  Xiao, Jian
收藏  |  浏览/下载:42/0  |  提交时间:2021/11/04
Furmonertinib (Alflutinib, AST2818) is a potential positive control drug comparable to rifampin for evaluation of CYP3A4 induction in sandwich-cultured primary human hepatocytes 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:  Wu, Ya-li;  Xue, Ya-ru;  Guo, Zi-tao;  Chen, Zhen-dong;  Ge, Xin-yu
收藏  |  浏览/下载:22/0  |  提交时间:2021/08/17
Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Jiang, Kai-long;  Tong, Le-xian;  Wang, Tao;  Wang, Han-lin;  Hu, Xiao-bei
收藏  |  浏览/下载:51/0  |  提交时间:2021/05/24
A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia 期刊论文
Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1
作者:  Xiao,Shifu;  Chan,Piu;  Wang,Tao;  Hong,Zhen;  Wang,Shuzhen
收藏  |  浏览/下载:148/0  |  提交时间:2021/05/24
Design, Synthesis, and Biological Evaluation of Orally Bioavailable CHK1 Inhibitors Active against Acute Myeloid Leukemia 期刊论文
CHEMMEDCHEM, 2021, 页码: 12
作者:  Jin, Tingting;  Wang, Peipei;  Long, Xiubing;  Jiang, Kailong;  Song, Pinrao
收藏  |  浏览/下载:133/0  |  提交时间:2021/05/24
G protein-coupled receptors: structure- and function-based drug discovery 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 27
作者:  Yang, Dehua;  Zhou, Qingtong;  Labroska, Viktorija;  Qin, Shanshan;  Darbalaei, Sanaz
收藏  |  浏览/下载:23/0  |  提交时间:2021/05/24
miR-552-3p modulates transcriptional activities of FXR and LXR to ameliorate hepatic glycolipid metabolism disorder 期刊论文
JOURNAL OF HEPATOLOGY, 2021, 卷号: 74, 期号: 1, 页码: 8-19
作者:  Fan, Lei;  Lai, Rongtao;  Ma, Ningning;  Dong, Yunxia;  Li, Yu
收藏  |  浏览/下载:41/0  |  提交时间:2021/05/24


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