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科研机构
上海药物研究所 [18]
内容类型
期刊论文 [18]
发表日期
2021 [1]
2020 [1]
2019 [2]
2018 [7]
2017 [1]
2016 [2]
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Itraconazole and rifampicin, as CYP3A modulators but not P-gp modulators, affect the pharmacokinetics of almonertinib and active metabolite HAS-719 in healthy volunteers
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Liu, Lu
;
Li, Wei
;
Yang, Le
;
Guo, Zi-tao
;
Xue, Hao
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2021/08/17
almonertinib
itraconazole
rifampicin
drug metabolism
drug interaction
CYP3A
P-gp
pharmacokinetics
Dihydro-stilbene gigantol relieves CCl4-induced hepatic oxidative stress and inflammation in mice via inhibiting C5b-9 formation in the liver
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 14
作者:
Xue, Ya-ru
;
Yao, Sheng
;
Liu, Qian
;
Peng, Zhao-liang
;
Deng, Qiang-qiang
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2020/07/01
gigantol
Chinese traditional medicine
liver injury
oxidative stress
inflammation
label-free proteomic
complement and coagulation cascades
terminal complement complex
Self-Assembled 2D Glycoclusters for the Targeted Delivery of Theranostic Agents to Triple-Negative Breast Cancer Cells
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2019, 卷号: 11, 期号: 25, 页码: 22181-22187
作者:
Hu, Xi-Le
;
Ca, Quanyu
;
Gao, Jie
;
Field, Robert A.
;
Chen, Guo-Rong
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
self-assembly
2D material
glycocluster
theranostics
breast cancer
Self-Assembled Thin-Layer Glycomaterials With a Proper Shell Thickness for Targeted and Activatable Cell Imaging
期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 7
作者:
Zhang, Chao
;
Wang, Guanzhen
;
Han, Hai-Hao
;
Hu, Xi-Le
;
Field, Robert A.
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/07/01
fluorescence
precision
imaging
activatable
receptor
18β-Glycyrrhetinic acid protects against alpha-naphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway
期刊论文
Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1865-1873
作者:
Wu, Shou-Yan
;
Cui, Shi-Chao
;
Wang, Le
;
Zhang, Yi-Ting
;
Yan, Xiao-Xia
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2019/01/08
18 beta-Glycyrrhetinic acid protects against alpha-naphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 12, 页码: 1865-1873
作者:
Wu, Shou-yan
;
Cui, Shi-chao
;
Wang, Le
;
Zhang, Yi-ying
;
Yan, Xiao-xia
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
hepatoprotective effect
cholestatic liver injury
18 beta-glycyrrhetinic acid (18b-GA)
FXR
Sirt1
bile acid transporters
Different structures of berberine and five other protoberberine alkaloids that affect P-glycoprotein-mediated efflux capacity
期刊论文
Acta pharmacologica Sinica, 2018
作者:
Zhang, Yi-Ting
;
Yu, Yu-Qi
;
Yan, Xiao-Xia
;
Wang, Wen-Jie
;
Tian, Xiao-Ting
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2019/01/08
Antibacterial sorbicillin and diketopiperazines from the endogenous fungus Penicillium sp GD6 associated Chinese mangrove Bruguiera gymnorrhiza
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2018, 卷号: 16, 期号: 5, 页码: 358-365
作者:
Jiang Cheng-Shi
;
Zhou Zhen-Fang
;
Yang Xiao-Hong
;
Lan Le-Fu
;
Gu Yu-Cheng
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Mangrove
Penicillium sp.
Sorbicillin derivative
Diketopiperazine alkaloids
Structural, stereochemical, and bioactive studies of cembranoids from Chinese soft coral &ITSarcophyton trocheliophorum&IT
期刊论文
TETRAHEDRON, 2018, 卷号: 74, 期号: 15, 页码: 1933-1941
作者:
Liang, Lin-Fu
;
Kurtan, Tibor
;
Mandi, Attila
;
Yao, Li-Gong
;
Li, Jia
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Sarcophyton trocheliophorum
Cembranoid
Structure elucidation
Absolute configuration
Biological activities
Racemic trinorsesquiterpenoids from the Beihai sponge Spongia officinalis: structure and biomimetic total synthesis
期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2018, 卷号: 5, 期号: 6, 页码: 1022-1027
作者:
Sun, Dong-Yu
;
Han, Guan-Ying
;
Yang, Na-Na
;
Lan, Le-Fu
;
Li, Xu-Wen
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
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