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科研机构
上海药物研究所 [66]
内容类型
期刊论文 [64]
会议论文 [2]
发表日期
2021 [7]
2020 [3]
2019 [1]
2018 [9]
2016 [5]
2015 [4]
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Beshanzoides A-D, unprecedented cycloheptanone-containing polyketides from Penicillium commune P-4-1, an endophytic fungus of the endangered conifer Abies beshanzuensis
期刊论文
RSC ADVANCES, 2021, 卷号: 11, 期号: 63, 页码: 39781-39789
作者:
Chen, Hao-Wei
;
Jiang, Chun-Xiao
;
Li, Jiyang
;
Li, Na
;
Zang, Yi
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2022/01/18
STING inhibitor ameliorates LPS-induced ALI by preventing vascular endothelial cells-mediated immune cells chemotaxis and adhesion
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Wu, Bing
;
Xu, Meng-meng
;
Fan, Chen
;
Feng, Chun-lan
;
Lu, Qiu-kai
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2022/01/18
acute lung injury
STING
vascular endothelial cells
inflammatory cytokines
chemokines
chemotaxis
Theoretical study and application of 2-phenyl-1,3,4-thiadiazole derivatives with optical and inhibitory activity against SHP1
期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2021, 页码: 14
作者:
Zhang, Chun
;
Sun, Yi-Tao
;
Gao, Li-Xin
;
Feng, Bo
;
Yan, Xue
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/01/18
Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13
作者:
Meng, Xiang-Dong
;
Gao, Li-Xin
;
Wang, Zhi-Jia
;
Feng, Bo
;
Zhang, Chun
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/12/01
2,5-diphenyl-1,3,4-oxadiazole derivatives
SHP2
Inhibitors
Structure-activity relationships (SAR)
Synthesis of 5-Phenyl-1,3,4-thiadiazole Derivatives and Their Biochemical Evaluation against Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase 1 (SHP1)
期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3097-3105
作者:
Yu Lijie
;
Feng Bo
;
Wang Zhijia
;
Gao Lixin
;
Zhang Chun
收藏
  |  
浏览/下载:242/0
  |  
提交时间:2021/11/04
5-phenyl-1,3,4-thiadiazole derivatives
Src homology 2 domain-containing protein tyrosine phosphatase 1 (SHP1)
inhibitors
structure-activity relationships
Inhibition of PDE4 by apremilast attenuates skin fibrosis through directly suppressing activation of M1 and T cells
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Lu, Qiu-kai
;
Fan, Chen
;
Xiang, Cai-gui
;
Wu, Bing
;
Lu, Hui-min
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2021/06/11
PDE4
apremilast
skin fibrosis
macrophages
Highly Oxygenated Triterpenoids and Diterpenoids from Fructus Rubi (Rubus chingii Hu) and Their NF-kappa B Inhibitory Effects
期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 7, 页码: 12
作者:
Wan, Jiang
;
Wang, Xiao-Juan
;
Guo, Nan
;
Wu, Xi-Ying
;
Xiong, Juan
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2021/05/24
Rubus chingii Hu
Rosaceae
triterpenoids
rubusacids
diterpenoids
rubusone
NF-κ
B
Therapy for Apnoea of Prematurity: A Retrospective Study on Effects of Standard Dose and Genetic Variability on Clinical Response to Caffeine Citrate in Chinese Preterm Infants
期刊论文
ADVANCES IN THERAPY, 2020, 页码: 20
作者:
He, Xin
;
Qiu, Jin-Chun
;
Lu, Ke-Yu
;
Guo, Hong-Li
;
Li, Ling
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/12/24
Adenosine receptors
AHR
AOP
Caffeine
Phosphodiesterase
Polymorphism
Therapeutic drug monitoring
Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Zhang, Xiao-tuan
;
Hu, Xiao-bei
;
Wang, Han-lin
;
Kan, Wei-juan
;
Xu, Lei
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2020/12/24
DLBCL
BTK inhibitor
ibrutinib resistance
UPR
TUDCA
2-DG
Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Su, Hai-xia
;
Yao, Sheng
;
Zhao, Wen-feng
;
Li, Min-jun
;
Liu, Jia
收藏
  |  
浏览/下载:115/0
  |  
提交时间:2020/12/24
SARS-CoV-2
3CL protease
traditional Chinese medicines
Shuanghuanglian oral liquid
baicalin
baicalein
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