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中南林业科技大学 [3]
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期刊论文 [3]
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2017 [1]
2011 [1]
2010 [1]
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Efficient Accumulation and In Vitro Antitumor Activities of Triterpene Acids from Submerged Batch--Cultured Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes).
期刊论文
International Journal of Medicinal Mushrooms, 2017, 卷号: 19, 期号: 5, 页码: 419-431
作者:
Wang, Xiao-Ling
;
Ding, Zhong-Yang
;
Zhao, Yan
;
Liu, Gao-Qiang*
;
Zhou, Guo-Ying
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浏览/下载:4/0
  |  
提交时间:2019/12/28
Antitumor activity
Central composite design
Ganoderma lucidum
Medicinal mushrooms
Response surface methodology
Submerged fermentation
Triterpene acids
Response surface methodology for optimization of polysaccharides extraction by mild alkaline hydrolysis from fruiting body of medicinal mushroom,Ganoderma lucidum
期刊论文
JOURNAL OF MEDICINAL PLANTS RESEARCH, 2011, 卷号: 5, 期号: 10, 页码: 2064-2070
作者:
Liu, Gao-Qiang*
;
Zhao, Yan
;
Wang, Xiao-Ling
;
Zhu, Chao-Yang
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浏览/下载:2/0
  |  
提交时间:2019/12/28
Medicinal mushroom
Ganoderma lucidum
polysaccharides extraction
response surface methodology
central composite design
Use of response surface methodology to optimize critical medium components for biomass and extracellular polysaccharide production by Ganoderma sinense
期刊论文
AFRICAN JOURNAL OF MICROBIOLOGY RESEARCH, 2010, 卷号: 4, 期号: 24, 页码: 2735-2741
作者:
Liu, Gao-Qiang*
;
Lin, Qin-Lu
;
Ren, Guo-Pu
;
Han, Wen-Jun
;
Wang, Xiao-Ling
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提交时间:2019/12/28
Response surface methodology (RSM) was used to optimize the critical medium ingredients of Ganoderma sinense. A central composite design (CCD) was employed to determine the maximum biomass and extracellular polysaccharide (EPS) yields at optimum levels for glucose
peptone and KH2PO4. A mathematical model was then developed to show the effect of each medium composition and their interactions on the production of mycelial biomass and EPS. The model predicted the maximum biomass yield of 12.58 g/l that appeared at glucose
peptone
KH2PO4 of 42.0 5.28 and 0.77 g/l
respectively
while a maximum of EPS yield of 309.6 mg/l appeared at glucose
peptone
KH2PO4 of 45.4 4.98 and 0.79 g/l
respectively. These predicted values were also verified by validation experiments. The excellent correlation between predicted and measured values of each model justifies the validity of both the response models. The results of bioreactor fermentation also show that the optimized culture medium enhanced both biomass (13.01± 0.36 g/l) and EPS (352 ± 7.9 mg/l) production by G.sinense in a large-scale fermentation process.
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