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科研机构
湖南大学 [204]
内容类型
期刊论文 [182]
会议论文 [22]
发表日期
2019 [65]
2018 [53]
2017 [18]
2016 [20]
2015 [4]
2014 [1]
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Synthesis of Chalcone Derivatives Containing Furan or/and Pyran Ring as Neuraminidase Inhibitors
期刊论文
Chemical Research in Chinese Universities, 2019, 卷号: Vol.35 No.3, 页码: 395-402
作者:
Aiyu Chen
;
Yongdong Liang
;
Jiao Ye
;
Aixi Hu
;
Wenwen Lian
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  |  
浏览/下载:50/0
  |  
提交时间:2019/12/13
Chalcone derivative
Neuraminidase inhibitor
Molecular docking
Leptomeningeal metastasis after effective first-generation EGFR TKI treatment of advanced non-small cell lung cancer
期刊论文
LUNG CANCER, 2019, 卷号: Vol.127, 页码: 1-5
作者:
Wu, Ya-Lan
;
Zhao, Qian
;
Deng, Lei
;
Zhang, Yan
;
Zhou, Xiao-Juan
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  |  
浏览/下载:56/0
  |  
提交时间:2019/12/13
Non-small cell lung cancer
Leptomeningeal metastasis
Epidermal growth factor receptor tyrosine kinase inhibitor
Exon 19 deletion
L858R
Small molecules as inhibitors of PCSK9: Current status and future challenges
期刊论文
European Journal of Medicinal Chemistry, 2019, 卷号: Vol.162, 页码: 212-233
作者:
Shengtao Xu
;
Shanshan Luo
;
Zheying Zhu
;
Jinyi Xu
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  |  
浏览/下载:11/0
  |  
提交时间:2019/12/13
PCSK9
protein
Inhibitor
Small-molecule
LDL-C
Hypercholesterolemia
Natural
products
Patent
Fluorometric determination of the activity of uracil-DNA glycosylase by using graphene oxide and exonuclease I assisted signal amplification.
期刊论文
Microchimica Acta, 2019, 卷号: Vol.186 No.2, 页码: 1
作者:
Chen, Mingjian
;
Li, Wenkai
;
Ma, Changbei
;
Wu, Kefeng
;
He, Hailun
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  |  
浏览/下载:119/0
  |  
提交时间:2019/12/13
Activity
Fluorescence
Inhibitor
Uracil-DNA glycosylase
Pharmacologic characterization of fluzoparib, a novel poly polymerase inhibitor undergoing clinical trials
期刊论文
Cancer Science, 2019, 卷号: Vol.110 No.3, 页码: 1064-1075
作者:
Lei Wang
;
Changyong Yang
;
Chengying Xie
;
Jiahua Jiang
;
Mingzhao Gao
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  |  
浏览/下载:12/0
  |  
提交时间:2019/12/13
antitumor activity
fluzoparib
pharmacokinetics
poly(ADP‐ribose) polymerase
toxicity
Defensins, a novel type of animal toxin-like potassium channel inhibitor
期刊论文
TOXICON, 2019, 卷号: Vol.157, 页码: 101-105
作者:
Zhao, Yonghui
;
Chen, Zongyun
;
Cao, Zhijian
;
Li, Wenxin
;
Wu, Yingliang
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  |  
浏览/下载:2/0
  |  
提交时间:2019/12/13
Animal toxin
Defensin
Inhibitor
Modifier
Blocker
Potassium channel
Plant-derived RNAi therapeutics: A strategic inhibitor of HBsAg
期刊论文
Biomaterials, 2019, 卷号: Vol.210, 页码: 83-93
作者:
Shuo Zhang
;
Xiaolin Sang
;
Dongxia Hou
;
Jinmei Chen
;
Hongwei Gu
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  |  
浏览/下载:13/0
  |  
提交时间:2019/12/13
RNAi
CHB
HBsAg
Artificial miRNA
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice.
期刊论文
Acta pharmacologica Sinica, 2019
作者:
Ting-Ting Zhou
;
Tong Zhao
;
Fei Ma
;
Yi-Nan Zhang
;
Jing Jiang
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  |  
浏览/下载:16/0
  |  
提交时间:2019/12/13
(E)-3-(2-(quinoline-4-yl)vinyl)-1H-indol-6-ol (QVO)
4-[2-(1H-indol-3-yl)vinyl]quinoline (IVQ)
AMPK signaling pathway
hepatic gluconeogenesis
prodrug
type 2 diabetes mellitus
A low-molecular-weight compound exerts anticancer activity against breast and lung cancers by disrupting EGFR/Eps8 complex formation
期刊论文
Journal of Experimental & Clinical Cancer Research, 2019, 卷号: Vol.38 No.1
作者:
Meifang Li
;
Jilong Yang
;
Lenghe Zhang
;
Sanfang Tu
;
Xuan Zhou
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/13
Epidermal growth factor receptor (EGFR)
Epidermal growth factor receptor pathway substrate 8 (Eps8)
Breast cancer
NSCLC, small-molecule inhibitor
4-aminoazobenzene modified natural glucomannan as a green eco-friendly inhibitor for the mild steel in 0.5 M HCl solution.
期刊论文
Corrosion Science, 2019, 卷号: Vol.151, 页码: 132-142
作者:
Luo, XH
;
Ci, CG
;
Li, J
;
Lin, KD
;
Du, S
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  |  
浏览/下载:20/0
  |  
提交时间:2019/12/13
Corrosion inhibition
Green inhibitor
HCl
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