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Anti-apoptotic effect of the Shh signaling pathway in cigarette smoke extract induced MLE 12 apoptosis 期刊论文
Tobacco Induced Diseases, 2019, 卷号: 17, 期号: June, 页码: 49
作者:  Li, Jinhua;  Zong, Dandan;  Chen, Yan*;  Chen, Ping*
收藏  |  浏览/下载:14/0  |  提交时间:2019/12/03
IL-9 and Th9 cells in health and diseases—From tolerance to immunopathology 期刊论文
Cytokine and Growth Factor Reviews, 2017, 卷号: 37, 页码: 47-55
作者:  Li, Junhui;  Chen, Shuqiu;  Xiao, Xiang;  Zhao, Yong;  Ding, Wenjun
收藏  |  浏览/下载:20/0  |  提交时间:2019/12/03
TNFRSF  Tumor necrosis factor receptor super family  GITR  Glucocorticoid-induced tumor necrosis factor receptor  DR3  Death receptor 3  ILC2  Type II innate lymph cells  CNS  Conserved non-coding sequences  TSS  Transcription start site  TCR  T cell receptor  NICD  Notch intracellular domain  CIS  Cytokine-induced SH-2  SOCS  Suppressor of cytokine signaling  NIK  NF-Kb inducing kinase  TL1A  TNF-like ligand 1A  IBD  Inflammatory bowel diseases  MS  Multiple sclerosis  SLE  Systemic lupus erythematosus  RA  Rheumatic arthritis  EAE  Experimental autoimmune encephalomyelitis  MOG  Myelin oligodendrocyte glycoprotein  IRF4  IFN-regulation factor 4  mAb  Monoclonal antibody  Th9  Transcription mechanism  Immunity and immunopathology  Therapeutic purposes  
Metformin, beyond an insulin sensitizer, targeting heart and pancreatic β cells 期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 8, 页码: 1984-1990
作者:  Yang, Xin;  Xu, Zhipeng;  Zhang, Chunlan;  Cai, Zixin;  Zhang, Jingjing*
收藏  |  浏览/下载:37/0  |  提交时间:2019/12/03
A1c  glycated hemoglobin  AACE  American Association of Clinical Endocrinologists  ACC  acetyl-CoA carboxylase  ADA  American Diabetes Association  Akt/PKB  tyrosine kinase/protein kinase B  AMP  adenosine monophosphate  AMPK  adenosine monophosphate-activated protein  Ang II  angiotensin II  ATP  adenosine triphosphate  BAT  brown adipose tissue  CHOP  CEBP-homologous protein  CEBP  CCAAT enhancer binding protein  CoA  coenzyme A  DPP  Diabetes Prevention Program  EASD  European Association for the Study of Diabetes  eNOS  endothelial nitric oxide synthase  ER  endoplasmic reticulum  FDA  Food and Drug Administration  FFA  free fatty acid  FOXO1  forkhead box protein O1  G6P  glucose 6-phosphate  GDM  gestational diabetes mellitus  GIPR  glucose-dependent insulinotropic polypeptide receptor  GLP-1R  glucagon-like peptide-1 receptor  GLUT1  glucose transporter-1  GLUT4  glucose transporter type 4  GLUTs  glucose transporters  G6P  glucose 6-phosphate, glucose transporter-1  GPR40  G protein-coupled receptor 40  HbA1c  hemoglobin A1c  HGP  hepatic glucose production  HSL  hormone sensitive lipase  IL-6  interleukin 6  INS-1  insulinoma cells in rat  IR  insulin resistance  IRS-1  insulin receptor substrate 1  JNK  c-Jun. N-terminal kinase  Kir6.2  inwardly rectifying potassium/kalium channel  LDs  lipid droplets  LDL  low density lipoprotein  LV  left ventricular  MIN6 cells  mouse insulinoma cells  MAPK  mitogen-activated protein kinases  mPTP  mitochondrial permeability transition pore opening  mTOR  mammalian target of rapamycin  NADPH  nicotinamide adenine dinucleotide phosphate  NF-kappaB  nuclear factors-kappa B  NIT-1 cells  insulinoma cells  p70S6K  p70 ribosomal S6 kinase  PA  palmitic acid  NOS  NADPH oxidase  p38 MAPK  p38 mitogen-activated protein kinase  PA  palmitic acid  PCOS  polycystic ovary syndrome  PGC-1α  peroxisome proliferator-activated receptor-g coactivator-1α  PI3K  phosphatidylinositol 3-kinase  PKB  protein kinase B  PKC  protein kinase C  PPARα  peroxisome-proliferator activated receptor α  PTP  permeability transition pore  RCT  randomized controlled trial  RISK  reperfusion injury salvage kinase  ROS  reactive oxygen species  SERCA2  reticulum sarcoplasmic Ca2 +-ATPase  RISK  reperfusion injury salvage kinase  Smad3  mothers against decapentaplegic homolog 3  SRC-2  steroid receptor coactivator 2  T1DM  Type 1 diabetes mellitus  T2DM  Type 2 diabetes mellitus  TGFβ1  transforming growth factor β1  TLR4  Toll-like receptor  TNF-α  tumor necrosis factor α  TR4  testicular receptor 4  UKPDS  United Kingdom Prospective Diabetes Study  VLDL  very low density lipoprotein  Metformin  Pancreatic β Cells  Heart failure  Insulin sensitizer  
Th9 cells and IL-9 in autoimmune disorders: Pathogenesis and therapeutic potentials 期刊论文
Human Immunology, 2017, 卷号: 78, 期号: 2, 页码: 120-128
作者:  Deng, Yaxiong;  Wang, Zijun;  Chang, Christopher;  Lu, Liwei;  Sing Lau, Chak
收藏  |  浏览/下载:22/0  |  提交时间:2019/12/03
IL  interleukin  TGF-β  transforming growth factor β  SLE  systemic lupus erythematosus  MS  multiple sclerosis  IBD  inflammatory bowel diseases  RA  rheumatoid arthritis  mAb  monoclonal antibody  IFN-γ  interferon gamma  TNF-α  tumor necrosis factor alpha  Tregs  regulatory T cells  EAE  experimental autoimmune encephalitis  ETS  E26-transformation-specific  STAT  activators of transcription  JAK  Janus kinase  NO  nitric oxide  LPS  lipopolysaccharide  ILC2  type II innate lymphoid cells  ROI  reactive oxygen intermediates  TPO  thrombopoietin  EPO  hemopoietin  SCF  stem cell factor  ASM  airway smooth muscle  SLEDAI  SLE disease activity index  dsDNA  double-stranded DNA  CNS  central nervous system  MOG  myelin oligodendrocyte glycoprotein  CCL20  chemokine ligand 20  RR-MS  relapsing-remitting multiple sclerosis  CD  Crohn’s disease  UC  ulcerative colitis  CIA  collagen-induced arthritis  Th9  IL-9  Differentiation  Autoimmune disease  Treatments  
Forecasting the volatility of crude oil futures using HAR-type models with structural breaks 期刊论文
Energy Economics, 2016, 卷号: 59, 页码: 400-413
作者:  Wen, Fenghua;  Gong, Xu;  Cai, Shenghua*
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/03
Bridges between mitochondrial oxidative stress, ER stress and mTOR signaling in pancreatic β cells 期刊论文
Cellular Signalling, 2016, 卷号: 28, 期号: 8, 页码: 1099-1104
作者:  Wang, Jing;  Yang, Xin;  Zhang, Jingjing*
收藏  |  浏览/下载:28/0  |  提交时间:2019/12/03
4E-BP1  4E binding protein  AMPK  AMP-activated protein kinase  ATF6  activating transcription factor 6  ATP  adenosine triphosphate  DEPTOR  DEP domain containing mTOR-interacting protein  CI  complexes I  CII  complex II  CIII  complex III  CIV  complex IV  CV  complex V  eIF2α  Eukaryotic Initiation Factor 2α  ER  Endoplasmic Reticulum  ERAD  ER-associated degradation  ERO1α  ER oxidoreductase 1 α  FoxO1  Forkhead box O1  GβL  G Protein β Subunit Like Protein  GRP78  78 kDa glucose-regulated protein precursor  GSIS  glucose-stimulated insulin secretion  IRE1  Inositol-requiring enzyme 1  IRS1  Insulin receptor substrate 1  IRS2  Insulin receptor substrate 2  mLST8  mammalian lethal with sec-13 protein 8  mSin1  the mammalian stress-activated MAP kinase-interaction protein 1  mtDNA  mitochondrial deoxyribonucleic acid  mTOR  mammalian TOR  mTORC1  mTOR complex 1  mTORC2  mTOR complex 2  NADPH oxidase  Nicotinamide adenine dinucleotide phosphate-oxidase  NOS  nitric oxide synthase  O2–·  superoxide anion  H2O2  hydrogen peroxide  OH·  hydroxyl radical  3O2  triplet-state molecular oxygen  OXPHOS  oxidative phosphorylation  CAT  catalase  GPx  glutathioneperoxidase  PERK  Protein kinase R-like endoplasmic reticulum kinase  PDI  ER protein disulfide isomerases  PI3K  the phosphoinositide3-kinase  PRAS40  40-kDa proline-rich Akt substrate  PRAS40  the 40-kDa proline-rich Akt substrate  PROTOR  the protein observed with RICTOR  RAPTOR  regulatory-associated protein of mTOR  RICTOR  The rapamycin-insensitive companion of mTOR  REDD1  DNA damage response 1  RNS  reactive nitrogen species  ROS  reactive oxygen species  RNS  reactive nitrogen species  S6K  S6 kinase  SOD  superoxidedismutase  T1DM  Type 1 diabetes mellitus  T2DM  Type 2 diabetes mellitus  TOR  the target of rapamycin  TSC2  Tuberous sclerosis 2  UPR  unfolded protein response  Mitochondrial oxidative stress  ER stress  mTOR  Pancreatic β cells  
Suppression of Type I Collagen Expression by miR-29b Via PI3K, Akt, and Sp1 Pathway, Part II: An In Vivo Investigation. 期刊论文
Investigative Ophthalmology and Visual Science, 2015, 卷号: 56, 期号: 10, 页码: 6019-6028
作者:  Yu, Juan;  Luo, Haomin;  Li, Ning;  Duan, Xuanchu*
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/03
Epigenetic mechanisms: An emerging role in pathogenesis and its therapeutic potential in systemic sclerosis 期刊论文
The International Journal of Biochemistry & Cell Biology, 2015, 卷号: 67, 页码: 92-100
作者:  Luo, Yangyang;  Wang, Yong;  Shu, Ye;  Lu, Qianjin;  Xiao, Rong*
收藏  |  浏览/下载:13/0  |  提交时间:2019/12/03
SSc  systemic sclerosis  SRC  scleroderma renal crisis  PAH  pulmonary arterial hypertension  SMR  standardized mortality ratio  DNMTs  DNA methyltransferases  SAM  S-adenosyl-methionine  5mC  5-methylcytosine  MBD  methyl-CpG-binding domain  Tet  ten–eleven translocation  HATs  histone acetyltransferases  HDACs  histone deacetylases  MiRNAs  microRNAs  MZ  monozygotic  DZ  dizygotic  MVECs  microvascular endothelial cells  FBs  fibroblasts  JAMs  junctional adhesion molecules  CTGF  connective tissue growth facto  TGF-β  transforming growth factor beta  CCN2  connective tissue growth factor  Fli1  Friend leukemia integration-1  TF  transcription factor  PECAM  platelet/endothelial cell adhesion molecule  PDGF  platelet derived growth factor  S1P1  sphingosin 1 phosphate  CXCL5  CXC chemokine ligand-5  BMPs  bone morphogenetic proteins  BMPRII  bone morphogenetic protein type II receptor  ET-1  endotheline-1  uPA  urokinase-type plasminogen activator  MBD  methyl-CpG-binding domain protein  ICAM  intercellular adhesion molecule  KLF5  Kruppel-like factor 5  Tregs  regulatory T cells  Runx1  Runt-related transcription factor 1  FOXP3  forkhead box protein 3 gene  ECM  extra cellular matrix  PDGF  platelet-derived growth factor  dSSc  diffuse systemic sclerosis  lSSc  limited systemic sclerosis  PCAF  protein-associated factor  Egr-1  early growth response 1  DDR2  discoidin domain receptor 2  TAB1  TGF-β activated kinase 1 binding protein 1  BAFF  B cell-activating factor  TSP-2  thrombospondin-2  MRTSS  Modified Rodnan total skin score  SDAI  Valentini scleroderma disease activity index  HC  healthy controls  SLE  systemic lupus erythematosus  SSD  scleroderma spectrum disorder  MTX  methylaminopterin  CYC  cyclophosphamide  MMF  mycophenolate mofetil  ACE  angiotensin converting enzyme  NO  nitric oxide  Systemic sclerosis  Epigenetic mechanisms  Biomarker  Therapy  
DNAJB13, a type II HSP40 family member, localizes to the spermatids and spermatozoa during mouse spermatogenesis 期刊论文
BMC Developmental Biology, 2014, 卷号: 14, 期号: 1, 页码: 38
作者:  Li, Weina;  Liu, Gang*
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/03
Exploring the relationship between 5′AMP-activated protein kinase and markers related to type 2 diabetes mellitus 期刊论文
Talanta, 2013, 卷号: 110, 页码: 1-7
作者:  Huang, Jian-Hua;  He, Rui-Hua;  Yi, Lun-Zhao;  Xie, Hua-Lin;  Cao, Dong-sheng
收藏  |  浏览/下载:17/0  |  提交时间:2019/12/03


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