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Discover 4 beta-NH-(6-aminoindole)-4-desoxy-podophyllotoxin with nanomolar-potency antitumor activity by improving the tubulin binding affinity on the basis of a potential binding site nearby colchicine domain 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 170, 页码: 73-86
作者:  Zhao, Wei;  He, Long;  Xiang, Tian-Le;  Tang, Ya-Jie
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/11
Discover 4β-NH-(6-aminoindole)-4-desoxy-podophyllotoxin with nanomolar-potency antitumor activity by improving the tubulin binding affinity on the basis of a potential binding site nearby colchicine domain 期刊论文
European Journal of Medicinal Chemistry, 2019, 页码: 73-86
作者:  Zhao W.;  He L.;  Xiang T.-L.;  Tang Y.-J.
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/11
Molecular modeling and chemometric analysis of osteoporosis calmodulin-TRPV1 binding affinity by statistically characterizing complex interactions 期刊论文
JOURNAL OF CHEMOMETRICS, 2018, 卷号: 32, 期号: 5
作者:  Liu, Xudong;  Zhu, Limin;  Wang, Lei;  Yu, Lingzhi;  Gao, Cong
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/11
Enhancement in catalytic activity of Aspergillus niger XynB by selective site-directed mutagenesis of active site amino acids 期刊论文
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2018, 卷号: 102, 期号: 1, 页码: 249-260
作者:  Wu, Xiuyun;  Tian, Zhennan;  Jiang, Xukai;  Zhang, Qun;  Wang, Lushan
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/11
Rs4705342 polymorphism is involved in the tumorigenesis of HBV positive HCC by altering the binding affinity of HBV induced NF-kB with the promoter region of microRNA-143 期刊论文
JOURNAL OF CELLULAR BIOCHEMISTRY, 2018, 卷号: 119, 期号: 7, 页码: 5233-5242
作者:  Yin, Xiuli;  Sun, Shiying;  Zhao, Junyan;  Yang, Jing;  Lei, Xiaofei
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/11
Effects of mutants in bHLH region on structure stability and protein-DNA binding energy in DECs 期刊论文
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2017, 卷号: 35, 期号: 9, 页码: 1849-1862
作者:  Kong, Yi;  Wang, Zhen;  Jia, Yanfei;  Li, Ping;  Hao, Shuhua
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/12
Thermal responsiveness and binding affinity of cucurbit[7]uril terminal poly(N-isopropylacrylamide) 期刊论文
NEW JOURNAL OF CHEMISTRY, 2017, 卷号: 41, 期号: 24, 页码: 14831-14834
作者:  Hou, Shengzhen;  Chen, Hao;  Qiu, Xiumin;  Xu, Wenchao;  Tan, Yebang
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/12
Quantitative Determination of Substrate Binding Affinity Influenced by a Single Amino Acid Mutation in Cellulase Active-site Architecture Using Fluorescent Spectrometry 期刊论文
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2016, 卷号: 43, 期号: 11, 页码: 1086-1093
作者:  Wang Pei-Pei;  Zhang Li-Li;  Zhang Qing;  Wang Lu-Shan;  Chen Guan-Jun
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/16
Interplay between binding affinity and kinetics in protein-protein interactions 期刊论文
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2016, 卷号: 84, 期号: 7, 页码: 920-933
作者:  Cao, Huaiqing;  Huang, Yongqi;  Liu, Zhirong
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/16
Impact of donor binding on polymerization catalyzed by KfoC by regulating the affinity of enzyme for acceptor 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2016, 卷号: 1860, 期号: 4, 页码: 844-855
作者:  Xue, Jiajun;  Jin, Lan;  Zhang, Xinke;  Wang, Fengshan;  Ling, Peixue
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/17


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