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科研机构
上海药物研究所 [50]
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期刊论文 [49]
学位论文 [1]
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2021 [1]
2020 [5]
2019 [2]
2018 [3]
2017 [6]
2016 [4]
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Alteration of twinfilin1 expression underlies opioid withdrawal-induced remodeling of actin cytoskeleton at synapses and formation of aversive memory
期刊论文
MOLECULAR PSYCHIATRY, 2021, 页码: 19
作者:
Wang, Yu-Jun
;
Yu, Chuan
;
Wu, Wei-Wei
;
Ju, Yun-Yue
;
Liu, Yao
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2021/06/11
Inhibition of phosphatidylinositol kinase-III alpha induces or facilitates lysosome exocytosis from microglia.
期刊论文
NEUROREPORT, 2020, 卷号: 31, 期号: 10, 页码: 697-701
作者:
Mu, Shujing
;
Lim, Nastasia K. -H.
;
Huang, Fude
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/12/24
exocytosis
lysosome
microglia
phosphatidylinositols
Co-delivery of Cu(I) chelator and chemotherapeutics as a new strategy for tumor theranostic
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2020, 卷号: 321, 页码: 483-496
作者:
Sun, Tao
;
Zhang, Guangping
;
Guo, Zhongyuan
;
Chen, Qinjun
;
Zhang, Yujie
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  |  
浏览/下载:42/0
  |  
提交时间:2020/07/01
Cu chelator
Antiangiogenesis
Theranostic
Real-time reporting
Co-delivery
RIPK1 inhibitor ameliorates colitis by directly maintaining intestinal barrier homeostasis and regulating following IECs-immuno crosstalk
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 172, 页码: 16
作者:
Lu, Huimin
;
Li, Heng
;
Fan, Chen
;
Qi, Qing
;
Yan, Yuxi
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  |  
浏览/下载:44/0
  |  
提交时间:2020/07/01
RIPK1 inhibitor
Colitis
Barrier homeostasis
IECs-immunocytes crosstalk
Necroptosis
NF-kappa B
Cancer-Cell-Membrane-Coated Nanoparticles with a Yolk-Shell Structure Augment Cancer Chemotherapy
期刊论文
NANO LETTERS, 2020, 卷号: 20, 期号: 2, 页码: 936-946
作者:
Nie, Di
;
Dai, Zhuo
;
Li, Jialin
;
Yang, Yiwei
;
Xi, Ziyue
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  |  
浏览/下载:36/0
  |  
提交时间:2020/07/01
cancer cell membrane coating
yolk-shell structure
tumor penetration
membrane fusion
intracellular trafficking
perinuclear aggregation
Folded or Degraded in Endoplasmic Reticulum
期刊论文
REGULATION OF CANCER IMMUNE CHECKPOINTS: MOLECULAR AND CELLULAR MECHANISMS AND THERAPY, 2020, 卷号: 1248, 页码: 265-294
作者:
Li, Chushu
;
Xia, Bingqing
;
Wang, Sheng
;
Xu, Jie
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/12/24
Immune checkpoint proteins
Endoplasmic reticulum
Glycosylation
ER chaperones
ER enzymes
Protein folding
COPII
Vesicle trafficking
ER proteostasis
ER quality control
ER stress
UPR
ERAD
ERLAD
Immunotherapy
Cancer Cell Membrane-Camouflaged Nanorods with Endoplasmic Reticulum Targeting for Improved Antitumor Therapy
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2019, 卷号: 11, 期号: 50, 页码: 46614-46625
作者:
Zhang, Wei
;
Yu, Miaorong
;
Xi, Ziyue
;
Nie, Di
;
Dai, Zhuo
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/07/01
rod shape
endoplasmic reticulum-tatgeted
cancer cell membrane coating
intracellular trafficking
pancreatic tumor delivery
SHR-A1403, a novel c-Met antibody-drug conjugate, exerts encouraging anti-tumor activity in c-Met-overexpressing models
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 7, 页码: 971-979
作者:
Yang, Chang-yong
;
Wang, Lei
;
Sun, Xing
;
Tang, Mi
;
Quan, Hai-tian
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
SHR-A1403
c-Met ADC
anti-tumor
patient-derived xenograft (PDX)
molecular mechanisms
Ligand-activated epidermal growth factor receptor (EGFR) signaling governs endocytic trafficking of unliganded receptor monomers by non-canonical phosphorylation
期刊论文
The Journal of biological chemistry, 2018, 卷号: 293, 期号: 7, 页码: 2288-2301
作者:
Tanaka, Tomohiro
;
Zhou, Yue
;
Ozawa, Tatsuhiko
;
Okizono, Ryuya
;
Banba, Ayako
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  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Transport mechanism of lipid covered saquinavir pure drug nanoparticles in intestinal epithelium
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2018, 卷号: 269, 页码: 159-170
作者:
Xia, Dengning
;
He, Yuan
;
Li, Qiuxia
;
Hu, Cunde
;
Huang, Wei
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/01/08
Surface modification
Phospholipid bilayer
Nanodrug
Endocytosis
Transcytosis
P-type glycoprotein substrate
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