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科研机构
上海药物研究所 [100]
内容类型
期刊论文 [81]
项目 [15]
会议论文 [4]
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2021 [6]
2020 [8]
2019 [9]
2018 [6]
2017 [4]
2016 [3]
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Genetics &... [1]
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A simple and effective method for identification of Fraxini Cortex from different sources by multi-mode fingerprint combined with chemometrics
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 16
作者:
Long, Huali
;
Yao, Shuai
;
Tian, Wenshuai
;
Hou, Jinjun
;
Lei, Min
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/01/18
chemometrics
Fraxini Cortex
high-performance thin-layer chromatography
multi-mode fingerprint
ultra-high-performance liquid chromatography
Rapamycin recruits SIRT2 for FKBP12 deacetylation during mTOR activity modulation in innate immunity
期刊论文
ISCIENCE, 2021, 卷号: 24, 期号: 11, 页码: 22
作者:
Hu, Lin
;
Chen, Fuxian
;
Wu, Chao
;
Wang, Jun
;
Chen, Si-si
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/01/18
5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19
作者:
Wang, Shuni
;
Yang, Hong
;
Su, Mingbo
;
Lian, Fulin
;
Cong, Zhanqing
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2021/11/04
NSD2
Methyltransferase
HTS
Multiple myeloma
5-Aminonaphthalene derivatives
Inhibitor
Discovery of a Potential Liver Fibrosis Inhibitor from a Mushroom Endophytic Fungus by Genome Mining of a Silent Biosynthetic Gene Cluster
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 38, 页码: 11303-11310
作者:
Cheng, Jin-Tao
;
Wang, Han-Min
;
Yu, Jia-Hui
;
Sun, Chen-Fan
;
Cao, Fei
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  |  
浏览/下载:28/0
  |  
提交时间:2021/12/01
fungus
Calcarisporium arbuscula
natural product
gene cluster activation
liver fibrosis
Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18
作者:
Xu, Dandan
;
Sun, Deqiao
;
Wang, Wei
;
Peng, Xia
;
Zhan, Zhengsheng
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  |  
浏览/下载:45/0
  |  
提交时间:2021/08/17
Axl
Cancer
Inhibitor
Pyrrolo[2,3-d]pyrimidine
Discovery of a Pyrimidinedione Derivative as a Potent and Orally Bioavailable Axl Inhibitor
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 7, 页码: 3956-3975
作者:
Zhang, Hefeng
;
Peng, Xia
;
Dai, Yang
;
Shao, Jingwei
;
Ji, Yinchun
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  |  
浏览/下载:16/0
  |  
提交时间:2021/06/11
DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Dai, Meng-di
;
Wang, Yue-liang
;
Fan, Jun
;
Dai, Yang
;
Ji, Yin-chun
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/05/24
receptor tyrosine kinase
FGFR inhibitor
DW14383
antitumor activity
An electric-field-responsive paramagnetic contrast agent enhances the visualization of epileptic foci in mouse models of drug-resistant epilepsy
期刊论文
NATURE BIOMEDICAL ENGINEERING, 2020, 页码: 16
作者:
Wang, Cong
;
Sun, Wanbing
;
Zhang, Jun
;
Zhang, Jianping
;
Guo, Qinghua
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/12/21
Collaborative Innovation Cluster Project of Shanghai Municipal Commission of Health and Family Planning[2020CXJQ02]
项目
项目编号: 2020CXJQ02, 资助机构: Collaborative Innovation Cluster Project of Shanghai Municipal Commission of Health and Family Planning, 2020-
-
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  |  
浏览/下载:2/0
  |  
提交时间:2020/12/21
SAF-189s, a potent new-generation ROS1 inhibitor, is active against crizotinib-resistant ROS1 mutant-driven tumors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 7
作者:
Xia, Zong-jun
;
Ji, Yin-chun
;
Sun, De-qiao
;
Peng, Xia
;
Gao, Ying-lei
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  |  
浏览/下载:75/0
  |  
提交时间:2020/12/21
ROS1 kinase
ROS1 inhibitor
SAF-189s
lorlatinib
crizotinib resistance
G2032R mutant
NSCLC
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