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科研机构
福建物质结构研究所 [7]
内容类型
期刊论文 [7]
发表日期
2011 [2]
2010 [2]
2009 [1]
2008 [1]
2007 [1]
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Mimicry of the Regulatory Role of Urokinase in Lamellipodia Formation by Introduction of a Non-native Interdomain Disulfide Bond in Its Receptor
期刊论文
Journal of Biological Chemistry, 2011, 卷号: 286, 期号: 50, 页码: 43515-43526
H. Gardsvoll
;
M. Kjaergaard
;
B. Jacobsen
;
M. C. Kriegbaum
;
M. D. Huang
;
M. Ploug
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  |  
浏览/下载:421/0
  |  
提交时间:2012/06/06
plasminogen-activator receptor
breast-cancer
monoclonal-antibodies
cellular receptor
anthrax toxin
invasive foci
stromal cells
binding-site
in-vivo
vitronectin
Antitumor effects of cucurmosin in human chronic myeloid leukemia occur through cell cycle arrest and decrease the Bcl-2/Bax ratio to induce apoptosis
期刊论文
African Journal of Pharmacy and Pharmacology, 2011, 卷号: 5, 期号: 7, 页码: 985-992
J. M. Xie
;
W. Z. Que
;
M. H. Chen
;
J. C. Sun
;
T. B. Liu
;
H. L. Liu
;
M. Liu
;
A. Q. Yang
;
P. Yang
;
Y. L. Wang
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  |  
浏览/下载:44/0
  |  
提交时间:2012/06/06
Cucurmosin
chronic myeloid leukemia
k562 cells
apoptosis
ribosome-inactivating protein
cucurbita-moschata
oxidative stress
cancer cells
degradation
activation
sarcocarp
pathway
acid
Pentalysine beta-Carbonylphthalocyanine Zinc: An Effective Tumor-Targeting Photosensitizer for Photodynamic Therapy
期刊论文
Chemmedchem, 2010, 卷号: 5, 期号: 6, 页码: 890-898
Z. Chen, S. Y. Zhou, J. C. Chen, Y. C. Deng, Z. P. Luo, H. W. Chen, M. R. Hamblin and M. D. Huang
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  |  
浏览/下载:14/0
  |  
提交时间:2012/11/02
cancer
cytotoxicity
pharmacokinetics
photodynamic therapy
synthesis
disulfonated aluminum phthalocyanine
mitochondria-dependent apoptosis
intensity laser therapy
chinese-hamster cells
biological-activities
photochemical properties
different mechanisms
cancer
series
photofrin
Structure-based Engineering of Species Selectivity in the Interaction between Urokinase and Its Receptor IMPLICATION FOR PRECLINICAL CANCER THERAPY
期刊论文
Journal of Biological Chemistry, 2010, 卷号: 285, 期号: 14, 页码: 10982-10992
L. Lin, H. Gardsvoll, Q. Huai, M. D. Huang and M. Ploug
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  |  
浏览/下载:50/0
  |  
提交时间:2012/11/02
cellular-binding site
plasminogen-activator
anthrax toxin
combinatorial chemistry
functional epitope
ligand-binding
deficient
mice
tumor-cells
in-vivo
vitronectin
Applications of Peptide Conjugated Photosensitizers in Photodynamic Therapy
期刊论文
Progress in Biochemistry and Biophysics, 2009, 卷号: 36, 期号: 9, 页码: 1106-1113
H. W. Chen, J. C. Chen, N. S. Chen, J. L. Huang, J. D. Wang and M. D. Huang
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  |  
浏览/下载:22/0
  |  
提交时间:2012/11/06
photodynamic therapy
photosensitizer
cancer
targeted
peptide
chlorin-type photosensitizer
in-vitro
choroidal neovascularization
protoporphyrin-ix
tumors
cells
neuropilin-1
phthalocyanines
angiogenesis
receptors
Atomic resolution structure of cucurmosin, a novel type 1 ribosome-inactivating protein from the sarcocarp of Cucurbita moschata
期刊论文
Journal of Structural Biology, 2008, 卷号: 164, 期号: 1, 页码: 81-87
X. M. Hou
;
E. J. Meehan
;
J. M. Xie
;
M. D. Huang
;
M. H. Chen and L. Q. Chen
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  |  
浏览/下载:82/0
  |  
提交时间:2013/01/22
ribosome-inactivating protein
sequence
structure
Cucurbita moschata
cytotoxicity
cancer cells
molecular replacement
macromolecular structures
crystal-structure
melanoma-cells
trichosanthin
purification
refinement
plants
ricin
seeds
An anti-urokinase plasminogen activator receptor (uPAR) antibody: Crystal structure and binding epitope
期刊论文
Journal of Molecular Biology, 2007, 卷号: 365, 期号: 4, 页码: 1117-1129
Y. D. Li
;
G. Parry
;
L. Q. Chen
;
J. A. Callahan
;
D. E. Shaw
;
E. J. Meehan
;
A. P. Mazar
;
M. D. Huang
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2013/04/01
antibody
crystal structure
uPAR
ATN615
Fab
breast-cancer
tumor-growth
in-vivo
prognostic-significance
inhibitory antibody
colorectal-cancer
integrin function
potential
target
lysozyme complex
cells
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