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科研机构
福建物质结构研究所 [13]
内容类型
期刊论文 [11]
学位论文 [2]
发表日期
2011 [5]
2010 [2]
2008 [2]
2007 [3]
2006 [1]
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A specific protein disorder catalyzer of HIV-1 Nef
期刊论文
Bioorganic & Medicinal Chemistry, 2011, 卷号: 19, 期号: 24, 页码: 7401-7406
A. Lugari
;
S. Breuer
;
T. Coursindel
;
S. Opi
;
A. Restouin
;
X. L. Shi
;
A. Nazabal
;
B. E. Torbett
;
J. Martinez
;
Y. Collette
;
I. Parrot
;
S. T. Arold
;
X. Morelli
收藏
  |  
浏览/下载:490/0
  |  
提交时间:2012/06/06
HIV-1 Nef inhibitor
Molecular modeling
Thermostability
Mass
spectrometry
Protein-protein interaction inhibitor
sh3 domain
crystal-structure
amino-acid
pathogenesis
dynamics
complex
hck
Elucidation of the Contribution of Active Site and Exosite Interactions to Affinity and Specificity of Peptidylic Serine Protease Inhibitors Using Non-Natural Arginine Analogs
期刊论文
Molecular Pharmacology, 2011, 卷号: 80, 期号: 4, 页码: 585-597
M. Hosseini
;
L. G. Jiang
;
H. P. Sorensen
;
J. K. Jensen
;
A. Christensen
;
S. Fogh
;
C. Yuan
;
L. M.
;
ersen
;
M. D. Huang
;
P. A.
;
reasen
;
K. J. Jensen
收藏
  |  
浏览/下载:116/0
  |  
提交时间:2012/06/06
plasminogen-activator
species-specificity
binding surface
enzyme
identification
derivatives
antibodies
residue
domain
The Binding Mechanism of a Peptidic Cyclic Serine Protease Inhibitor
期刊论文
Journal of Molecular Biology, 2011, 卷号: 412, 期号: 2, 页码: 235-250
L. G. Jiang
;
A. S. P. Svane
;
H. P. Sorensen
;
J. K. Jensen
;
M. Hosseini
;
Z. Chen
;
C. Weydert
;
J. T. Nielsen
;
A. Christensen
;
C. Yuan
;
K. J. Jensen
;
N. C. Nielsen
;
A. Malmendal
;
M. D. Huang
;
P. A.
;
reasen
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2012/06/06
competitive inhibition
fibrinolysis
cancer
plasminogen activation system
sunflower seeds
urokinase
specificity
domain
compensation
compstatin
complexes
receptor
residue
Growth and characterization of piezo-/ferroelectric Pb(Mg(1/3)Nb(2/3))O(3)-PbTiO(3)-Bi(Zn(1/2)Ti(1/2))O(3) ternary single crystals
期刊论文
Journal of Crystal Growth, 2011, 卷号: 318, 期号: 1, 页码: 839-845
R. A. Belan
;
H. N. Tailor
;
X. F. Long
;
A. A. Bokov
;
Z. G. Ye
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2012/06/06
Groeth from high temperature solutions
Oxides
Perovskite
Bismuth
compounds
Dielectric materials
Ferroelectrics
domain-structures
phase-diagram
piezoelectrics
behavior
Preparation and Structure of a New Coagulation Factor XI Catalytic Domain for Drug Discovery
期刊论文
Chinese Journal of Structural Chemistry, 2011, 卷号: 30, 期号: 7, 页码: 1021-1029
L. G. Jiang
;
C. Yuan
;
H. W. Chen
;
Y. Wang
;
B. Y. Zhao
;
X. Zhang
;
M. D. Huang
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2012/06/06
human blood coagulation factor XI
crystal structure
serine proteases
inhibitors
plasma thromboplastin antecedent
blood-coagulation
binding-site
activation
mechanism
chymotrypsin
specificity
deficiency
thrombin
complex
Identification and biophysical assessment of the molecular recognition mechanisms between the human haemopoietic cell kinase Src homology domain 3 and ALG-2-interacting protein X
期刊论文
Biochemical Journal, 2010, 卷号: 431, 页码: 93-102
X. L. Shi, S. Opi, A. Lugari, A. Restouin, T. Coursindel, I. Parrot, J. Perez, E. Madore, P. Zimmermann, J. Corbeil, M. D. Huang, S. T. Arold, Y. Collette and X. Morelli
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2012/11/02
apoptosis-linked gene 2-interacting protein X (Alix)
haemopoietic cell
kinase (Hck)
protein-protein interaction
Src homology 3 domain (SH3
domain)
Src family kinase (SFK)
hiv-1 nef protein
hck sh3 domain
signal-transduction
crystal-structure
tyrosine kinases
family kinases
c-src
alix
binding
reveals
Trp(2313)-His(2315) of Factor VIII C2 Domain Is Involved in Membrane Binding STRUCTURE OF A COMPLEX BETWEEN THE C2 DOMAIN AND AN INHIBITOR OF MEMBRANE BINDING
期刊论文
Journal of Biological Chemistry, 2010, 卷号: 285, 期号: 12, 页码: 8824-8829
Z. Liu, L. Lin, C. Yuan, G. A. F. Nicolaes, L. Q. Chen, E. J. Meehan, B. Furie and M. D. Huang
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2012/11/02
coagulation-factor-viii
von-willebrand-factor
human-factor-v
crystal-structure
protein
identification
hemophilia
activation
mutation
surface
核糖体失活蛋白的结构生物学研究
学位论文
博士, 福建物质结构研究所: 中国科学院福建物质结构研究所, 2008
侯晓敏
收藏
  |  
浏览/下载:136/0
  |  
提交时间:2013/05/09
核糖体失活蛋白(RIPs)
晶体结构
X-ray序列
DNA测序
细胞毒性
Crystal structure of the fab fragment of an anti-factor IX antibody 10C12
期刊论文
Chinese Journal of Structural Chemistry, 2008, 卷号: 27, 期号: 8, 页码: 995-1001
X. L. Shi
;
T. Zeng and M. D. Huang
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2013/01/22
anticoagulant
10C12
factor IX
Gla domain
crystal structure
domain
binding
Structural basis of specificity of a peptidyl urokinase inhibitor, upain-1
期刊论文
Journal of Structural Biology, 2007, 卷号: 160, 期号: 1, 页码: 1-10
G. X. Zhao
;
C. Yuan
;
T. Wind
;
Z. X. Huang
;
P. A.
;
reasen
;
M. D. Huang
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2013/04/01
urokinase-type plasminogen activator
peptidyl inhibitor
crystal
structure
pharmacophore
activator pro-upa
plasminogen-activator
crystal-structure
single-chain
selective inhibitors
drug design
complex
receptor
system
domain
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