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浏览/检索结果: 共9条，第1-9条 帮助 限定条件 专题：北京大学    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery of a new class of highly potent necroptosis inhibitors targeting the mixed lineage kinase domain-like protein 期刊论文 CHEMICAL COMMUNICATIONS, 2017 Yan, Bo; Liu, Lei; Huang, Shaoqiang; Ren, Yan; Wang, Huayi; Yao, Zhenglin; Li, Lin; Chen, She; Wang, Xiaodong; Zhang, Zhiyuan 收藏  |  浏览/下载：4/0  |  提交时间：2017/12/03 CELL-DEATH  MLKL  NECROSIS  RIP3  INFLAMMATION  ACTIVATION   天然产物Kongensin A作为一种非经典的HSP90抑制剂阻断RIP3依赖性的程序性坏死 期刊论文 科学新闻, 2017 Dianrong Li; Chao Li; Lin Li; She Chen; Lei Wang; Qiang Li; Xiaodong Wang; 雷晓光; 沈志荣 收藏  |  浏览/下载：5/0  |  提交时间：2017/12/03 化学遗传学  天然产物  凋亡通路  死亡信号  受体蛋白  蛋白质折叠  二萜类  HSP90  Kongensin A  RIP3   Discovery of a Highly Potent, Selective, and Metabolically Stable Inhibitor of Receptor-Interacting Protein 1 (RIP1) for the Treatment of Systemic Inflammatory Response Syndrome 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2017 Ren, Yan; Su, Yaning; Sun, Liming; He, Sudan; Meng, Lingjun; Liao, Daohong; Liu, Xiao; Ma, Yongfen; Liu, Chunyan; Li, Sisi; Ruan, Hanying; Lei, Xiaoguang; Wang, Xiaodong; Zhang, Zhiyuan 收藏  |  浏览/下载：5/0  |  提交时间：2017/12/03 EXPERIMENTAL DISEASE-MODELS  CELL-DEATH  KINASE INHIBITORS  INDUCED SHOCK  NECROPTOSIS  NECROSIS  NECROSTATIN-1  SPECIFICITY  INJURY  ALPHA   CaMKII is a RIP3 substrate mediating ischemia- and oxidative stress-induced myocardial necroptosis 期刊论文 NATURE MEDICINE, 2016 Zhang, Ting; Zhang, Yan; Cui, Mingyao; Jin, Li; Wang, Yimei; Lv, Fengxiang; Liu, Yuli; Zheng, Wen; Shang, Haibao; Zhang, Jun; Zhang, Mao; Wu, Hongkun; Guo, Jiaojiao; Zhang, Xiuqin; Hu, Xinli; Cao, Chun-Mei; Xiao, Rui-Ping 收藏  |  浏览/下载：10/0  |  提交时间：2017/12/03 MITOCHONDRIAL PERMEABILITY TRANSITION  RECEPTOR INTERACTING PROTEIN-3  MIXED LINEAGE KINASE  CELL-DEATH  PROGRAMMED NECROSIS  REPERFUSION INJURY  HEART-FAILURE  DOMAIN-LIKE  ISCHEMIA/REPERFUSION INJURY  INDEPENDENT ACTIVATION   Cell apoptosis, autophagy and necroptosis in osteosarcoma treatment 期刊论文 ONCOTARGET, 2016 Li, Jing; Yang, Zuozhang; Li, Yi; Xia, Junfeng; Li, Dongqi; Li, Huiling; Ren, Mingyan; Liao, Yedan; Yu, Shunling; Chen, Yanjin; Yang, Yihao; Zhang, Ya 收藏  |  浏览/下载：8/0  |  提交时间：2017/12/03 apoptosis  autophagy  necroptosis  chemotherapy resistance  osteosarcoma  CELASTROL INDUCES APOPTOSIS  TRAIL-INDUCED APOPTOSIS  PROTEIN-KINASE 1  IN-VITRO  SIGNALING PATHWAY  LUNG METASTASIS  HMGB1-MEDIATED AUTOPHAGY  INHIBITS PROLIFERATION  MITOCHONDRIAL PATHWAY  PROTEASOME INHIBITOR   Natural Product Kongensin A is a Non-Canonical HSP90 Inhibitor that Blocks RIP3-dependent Necroptosis 期刊论文 Cell Chemical Biology, 2016 Li, Dianrong; Li, Chao; Li, Lin; Chen, She; Wang, Lei; Li, Qiang; Wang, Xiaodong; Lei, Xiaoguang; Shen, Zhirong 收藏  |  浏览/下载：4/0  |  提交时间：2017/12/04 MIXED LINEAGE KINASE  DOMAIN-LIKE PROTEIN  CELL-DEATH  PROGRAMMED NECROSIS  BIOORTHOGONAL LIGATION  MOLECULAR CHAPERONE  RIP3  CANCER  MLKL  COMPLEX   Using Small Molecules to Dissect Non-apoptotic Programmed Cell Death: Necroptosis, Ferroptosis, and Pyroptosis 期刊论文 CHEMBIOCHEM, 2015 Dong, Ting; Liao, Daohong; Liu, Xiaohui; Lei, Xiaoguang 收藏  |  浏览/下载：2/0  |  提交时间：2017/12/03 cancer  ferroptosis  necroptosis  programmed cell death  pyroptosis  signal transduction  MIXED LINEAGE KINASE  CHEMICAL GENETICS  INFECTED MACROPHAGES  CANCER-CELLS  RIP1 KINASE  DISEASE  NECROSIS  SALMONELLA  ACTIVATION  DAMAGE   Enhanced breast cancer therapy with nsPEFs and low concentrations of gemcitabine 期刊论文 cancer cell international, 2014 Wu, Shan; Guo, Jinsong; Wei, Wendong; Zhang, Jue; Fang, Jing; Beebe, Stephen J. 收藏  |  浏览/下载：4/0  |  提交时间：2015/11/10 Breast cancer  MCF-7  MDA-MB-231  Nanosecond pulsed electric fields (nsPEFs)  Non-thermal  Gemcitabine  Synergism  Clonogenics  Apoptosis  Necrosis (necroptosis)  PULSED ELECTRIC-FIELDS  PROGRAMMED NECROSIS  OVARIAN-CANCER  GROWTH-RATE  HUMAN-CELLS  IN-VITRO  NANOSECOND  APOPTOSIS  MECHANISMS  CARCINOMA   Pathogen blocks host death receptor signalling by arginine GlcNAcylation of death domains 期刊论文 nature, 2013 Li, Shan; Zhang, Li; Yao, Qing; Li, Lin; Dong, Na; Rong, Jie; Gao, Wenqing; Ding, Xiaojun; Sun, Liming; Chen, Xing; Chen, She; Shao, Feng 收藏  |  浏览/下载：5/0  |  提交时间：2015/11/16 NECROSIS-FACTOR RECEPTOR  TOLL-LIKE-RECEPTORS  BACTERIAL EFFECTOR  ESCHERICHIA-COLI  PATHWAYS  PROTEIN  TRADD  SUPERFAMILY  FAMILY  NLEB