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CORC

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Novel benzothiazinones (BTOs) as allosteric modulator or substrate competitive inhibitor of glycogen synthase kinase 3 beta (GSK-3 beta) with cellular activity of promoting glucose uptake 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 24, 页码: 5639-5643
作者:  Zhang, Peng;  Li, Shufen;  Gao, Yang;  Lu, Wenbo;  Huang, Ke
收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08
Discovery and Optimization of 4,5-Diarylisoxazoles as Potent Dual Inhibitors of Pyruvate Dehydrogenase Kinase and Heat Shock Protein 90 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 57, 期号: 23, 页码: 9832-9843
作者:  Meng, Tao;  Zhang, Dadong;  Xie, Zuoquan;  Yu, Ting;  Wu, Shuchao
收藏  |  浏览/下载：8/0  |  提交时间：2019/01/08
A Chemical Tuned Strategy to Develop Novel Irreversible EGFR-TK Inhibitors with Improved Safety and Pharmacokinetic Profiles 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 57, 期号: 23, 页码: 9889-9900
作者:  Xia, Guangxin;  Chen, Wenteng;  Zhang, Jing;  Shao, Jiaan;  Zhang, Yong
收藏  |  浏览/下载：31/0  |  提交时间：2019/01/08
Crucial Role of c-Jun Phosphorylation at Ser63/73 Mediated by PHLPP Protein Degradation in the Cheliensisin A Inhibition of Cell Transformation 期刊论文
CANCER PREVENTION RESEARCH, 2014, 卷号: 7, 期号: 12, 页码: 1270-1281
作者:  Zhu, Junlan;  Zhang, Jingjie;  Huang, Haishan;  Li, Jingxia;  Yu, Yonghui
收藏  |  浏览/下载：41/0  |  提交时间：2015/01/20
G226, a new epipolythiodioxopiperazine derivative, triggers DNA damage and apoptosis in human cancer cells in vitro via ROS generation 期刊论文
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 12, 页码: 1546-1555
作者:  He, Peng-xing;  Zhang, Jie;  Che, Yong-sheng;  He, Qiao-jun;  Chen, Yi
收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08
Identification and validation of p50 as the cellular target of eriocalyxin B 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 22, 页码: 11354-11364
作者:  Kong, Ling-Mei;  Deng, Xu;  Zuo, Zhi-Li;  Sun, Han-Dong;  Zhao, Qin-Shi
收藏  |  浏览/下载：19/0  |  提交时间：2015/06/17
Nanoassembly of Probucol Enables Novel Therapeutic Efficacy in the Suppression of Lung Metastasis of Breast Cancer 期刊论文
SMALL, 2014, 卷号: 10, 期号: 22, 页码: 4735-4745
作者:  Zhang, Zhiwen;  Cao, Haiqiang;  Jiang, Shijun;  Liu, Zeying;  He, Xinyu
收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08
Inhibition of Murine Bladder Cancer Cell Growth In Vitro by Photocontrollable siRNA Based on Upconversion Fluorescent Nanoparticles 期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 11
作者:  Guo, Huichen;  Yan, Dan;  Wei, Yanquan;  Han, Shichong;  Qian, Haisheng
收藏  |  浏览/下载：4/0  |  提交时间：2019/11/15
Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 87, 页码: 765-781
作者:  Chen, Danqi;  Shen, Aijun;  Li, Jian;  Shi, Feng;  Chen, Wuyan
收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08
Simultaneous targeting of PI3K delta and a PI3K delta-dependent MEK1/2-Erk1/2 pathway for therapy in pediatric B-cell acute lymphoblastic leukemia 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 21, 页码: 10732-10744
作者:  Wang, Xiang;  Zhang, Xi;  Li, Ben-shang;  Zhai, Xiaowen;  Yang, Zhuo
收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08

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