×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
南华大学 [8]
中南大学 [6]
西安交通大学 [3]
上海药物研究所 [2]
武汉大学 [2]
吉林大学白求恩第一医... [2]
更多...
内容类型
期刊论文 [27]
会议论文 [1]
发表日期
2018 [1]
2017 [6]
2015 [6]
2014 [5]
2013 [2]
2012 [2]
更多...
学科主题
Behavioral... [1]
Neuroscien... [1]
Pharmacolo... [1]
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共28条,第1-10条
帮助
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
Resibufogenin suppresses transforming growth factor-beta-activated kinase 1-mediated nuclear factor-kappa B activity through protein kinase C-dependent inhibition of glycogen synthase kinase 3
期刊论文
2018, 卷号: 109, 期号: 11, 页码: 3611-3622
作者:
Liu, Lu
;
Liu, Yang
;
Liu, Xiaojia
;
Zhang, Na
;
Mao, Genxiang
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/01/03
glycogen synthase kinase-3
nuclear factor-kappa B
protein kinase C
resibufogenin
transforming growth factor-beta-activated kinase 1
Metformin, beyond an insulin sensitizer, targeting heart and pancreatic β cells
期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 8, 页码: 1984-1990
作者:
Yang, Xin
;
Xu, Zhipeng
;
Zhang, Chunlan
;
Cai, Zixin
;
Zhang, Jingjing*
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/12/03
A1c
glycated hemoglobin
AACE
American Association of Clinical Endocrinologists
ACC
acetyl-CoA carboxylase
ADA
American Diabetes Association
Akt/PKB
tyrosine kinase/protein kinase B
AMP
adenosine monophosphate
AMPK
adenosine monophosphate-activated protein
Ang II
angiotensin II
ATP
adenosine triphosphate
BAT
brown adipose tissue
CHOP
CEBP-homologous protein
CEBP
CCAAT enhancer binding protein
CoA
coenzyme A
DPP
Diabetes Prevention Program
EASD
European Association for the Study of Diabetes
eNOS
endothelial nitric oxide synthase
ER
endoplasmic reticulum
FDA
Food and Drug Administration
FFA
free fatty acid
FOXO1
forkhead box protein O1
G6P
glucose 6-phosphate
GDM
gestational diabetes mellitus
GIPR
glucose-dependent insulinotropic polypeptide receptor
GLP-1R
glucagon-like peptide-1 receptor
GLUT1
glucose transporter-1
GLUT4
glucose transporter type 4
GLUTs
glucose transporters
G6P
glucose 6-phosphate, glucose transporter-1
GPR40
G protein-coupled receptor 40
HbA1c
hemoglobin A1c
HGP
hepatic glucose production
HSL
hormone sensitive lipase
IL-6
interleukin 6
INS-1
insulinoma cells in rat
IR
insulin resistance
IRS-1
insulin receptor substrate 1
JNK
c-Jun. N-terminal kinase
Kir6.2
inwardly rectifying potassium/kalium channel
LDs
lipid droplets
LDL
low density lipoprotein
LV
left ventricular
MIN6 cells
mouse insulinoma cells
MAPK
mitogen-activated protein kinases
mPTP
mitochondrial permeability transition pore opening
mTOR
mammalian target of rapamycin
NADPH
nicotinamide adenine dinucleotide phosphate
NF-kappaB
nuclear factors-kappa B
NIT-1 cells
insulinoma cells
p70S6K
p70 ribosomal S6 kinase
PA
palmitic acid
NOS
NADPH oxidase
p38 MAPK
p38 mitogen-activated protein kinase
PA
palmitic acid
PCOS
polycystic ovary syndrome
PGC-1α
peroxisome proliferator-activated receptor-g coactivator-1α
PI3K
phosphatidylinositol 3-kinase
PKB
protein kinase B
PKC
protein kinase C
PPARα
peroxisome-proliferator activated receptor α
PTP
permeability transition pore
RCT
randomized controlled trial
RISK
reperfusion injury salvage kinase
ROS
reactive oxygen species
SERCA2
reticulum sarcoplasmic Ca2 +-ATPase
RISK
reperfusion injury salvage kinase
Smad3
mothers against decapentaplegic homolog 3
SRC-2
steroid receptor coactivator 2
T1DM
Type 1 diabetes mellitus
T2DM
Type 2 diabetes mellitus
TGFβ1
transforming growth factor β1
TLR4
Toll-like receptor
TNF-α
tumor necrosis factor α
TR4
testicular receptor 4
UKPDS
United Kingdom Prospective Diabetes Study
VLDL
very low density lipoprotein
Metformin
Pancreatic β Cells
Heart failure
Insulin sensitizer
Aucubin and its hydrolytic derivative attenuate activation of hepatic stellate cells via modulation of TGF-β stimulation
期刊论文
Environmental Toxicology and Pharmacology, 2017, 卷号: 50, 页码: 234-239
作者:
Lv, Pei-Yu
;
Feng, Han
;
Huang, Wei-Hua
;
Tian, Ying-Ying
;
Wang, Ya-Qin
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/03
AU
aucubin
AUG
aucubigenin
Col I
collagen I
Col III
collagen III
ECM
extracellular matrix
α-SMA
alpha smooth muscle actin
LX-2
human hepatic stellate cell
TGF-β1
transforming growth factor-β1
CTGF
connective tissue growth factor
MDA
malondialdehyde
CAT
catalase
GSH-Px
glutathione peroxidase
SOD
superoxide dismutase
DPPH
1,1-diphenyl-2-picrylhydrazyl radical 2,2-diphenyl-1-(2,4,6-trinitrophenyl) hydrazyl
p38 MAPK
P38 mitogen activated protein kinase
Human hepatic stellate cells
Aucubin
Aucubigenin
Extracellular matrix
TGF-β1
RACK1 silencing attenuates renal fibrosis by inhibiting TGF-beta signaling
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2017, 卷号: 40, 页码: 1965-1970
作者:
Feng, Jie
;
Xie, Liyi
;
Kong, Ranran
;
Zhang, Yali
;
Shi, Kehui
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/11/26
renal fibrosis
transforming growth factor-beta 1
receptor for activated C-kinase 1
Resveratrol ameliorates diabetic nephropathy in rats through negative regulation of the p38 MAPK/TGF-beta 1 pathway
期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2017, 卷号: 13, 页码: 3223-3230
作者:
Qiao, Yuan
;
Gao, Ke
;
Wang, Yangwei
;
Wang, Xueliang
;
Cui, Bo
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/11/26
resveratrol
p38 mitogen-activated protein kinase/transforming growth factor beta 1 pathway
diabetic nephropathy
MIR-155 ALLEVIATES SEPTIC LUNG INJURY BY INDUCING AUTOPHAGY VIA INHIBITION OF TRANSFORMING GROWTH FACTOR-beta-ACTIVATED BINDING PROTEIN 2
期刊论文
SHOCK, 2017, 卷号: 48, 期号: 1
作者:
Liu, Fen
;
Nie, Cheng
;
Zhao, Ning
;
Wang, Yan
;
Liu, Yang
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
Autophagy
miR-155
septic lung injury
transforming growth factor-beta-activated kinase-1-binding protein 2
Myocardin: A novel player in atherosclerosis
期刊论文
Atherosclerosis, 2017, 卷号: 257, 页码: 266-278
作者:
Xia, Xiao-Dan
;
Zhou, Zhen
;
Yu, Xiao-Hua
;
Zheng, Xi-Long
;
Tang, Chao-Ke*
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/12/27
Myocardin
Atherosclerosis
Inflammation
Lipid metabolism
VSMC
Abca1
MYOCD
Myocardin
AS
atherosclerosis
SRF
serum response factor
VSMC
vascular smooth muscle cell
Mrtf-A/B
Myocardin-related transcription factors A/B
Mamstr
Mef2-activating SAP transcriptional protein
SAP domain
scaffold attachment factors A and B (SAF-A and -B), Acinus, and PIAS
MADS
MCM1, Agamous, Deficiens, SRF-box transcription factor
TAD
transactivation domain
NTD
N-terminal domain
Arp5
actin-related protein 5
Tead
TEA domain transcription factor
Foxo
forkhead transcription factor
Cdc7
cell division cycle 7
Mef2
myocyte-specific enhancer factor
Nfatc3
nuclear factor of activated T cells c3
hnRNPA1
heterogeneous nuclear ribonucleoprotein A1
Tet2
ten-eleven translocation-2
TGF-β
transforming growth factor-β
URR
upstream repressor region
Klf4
Kruppel-like factor4
PRR
platelet-derived growth factor-BB-responsive region
Pkcα
protein kinase C α
MSCs
mesenchymal stem cells
lncRNAs
long non-coding RNAs
MicroRNAs
small non-encoding RNAs
UTR
un-translated region
Abca1
ATP-binding cassette transporter A1
RCT
reverse cholesterol transport
Activation of AMPK by metformin inhibits TGF-beta-induced collagen production in mouse renal fibroblasts
期刊论文
LIFE SCIENCES, 2015, 卷号: 127, 期号: [db:dc_citation_issue], 页码: 59-65
作者:
Lu, Jiamei
;
Shi, Jianhua
;
Li, Manxiang
;
Gui, Baosong
;
Fu, Rongguo
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/02
Connective tissue growth factor (CTGF)
Transforming growth factor beta 1 (TGF-beta 1)
Renal fibroblasts
Collagen
Adenosine monophosphate-activated protein kinase (AMPK)
Epigenetic mechanisms: An emerging role in pathogenesis and its therapeutic potential in systemic sclerosis
期刊论文
The International Journal of Biochemistry & Cell Biology, 2015, 卷号: 67, 页码: 92-100
作者:
Luo, Yangyang
;
Wang, Yong
;
Shu, Ye
;
Lu, Qianjin
;
Xiao, Rong*
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/03
SSc
systemic sclerosis
SRC
scleroderma renal crisis
PAH
pulmonary arterial hypertension
SMR
standardized mortality ratio
DNMTs
DNA methyltransferases
SAM
S-adenosyl-methionine
5mC
5-methylcytosine
MBD
methyl-CpG-binding domain
Tet
ten–eleven translocation
HATs
histone acetyltransferases
HDACs
histone deacetylases
MiRNAs
microRNAs
MZ
monozygotic
DZ
dizygotic
MVECs
microvascular endothelial cells
FBs
fibroblasts
JAMs
junctional adhesion molecules
CTGF
connective tissue growth facto
TGF-β
transforming growth factor beta
CCN2
connective tissue growth factor
Fli1
Friend leukemia integration-1
TF
transcription factor
PECAM
platelet/endothelial cell adhesion molecule
PDGF
platelet derived growth factor
S1P1
sphingosin 1 phosphate
CXCL5
CXC chemokine ligand-5
BMPs
bone morphogenetic proteins
BMPRII
bone morphogenetic protein type II receptor
ET-1
endotheline-1
uPA
urokinase-type plasminogen activator
MBD
methyl-CpG-binding domain protein
ICAM
intercellular adhesion molecule
KLF5
Kruppel-like factor 5
Tregs
regulatory T cells
Runx1
Runt-related transcription factor 1
FOXP3
forkhead box protein 3 gene
ECM
extra cellular matrix
PDGF
platelet-derived growth factor
dSSc
diffuse systemic sclerosis
lSSc
limited systemic sclerosis
PCAF
protein-associated factor
Egr-1
early growth response 1
DDR2
discoidin domain receptor 2
TAB1
TGF-β activated kinase 1 binding protein 1
BAFF
B cell-activating factor
TSP-2
thrombospondin-2
MRTSS
Modified Rodnan total skin score
SDAI
Valentini scleroderma disease activity index
HC
healthy controls
SLE
systemic lupus erythematosus
SSD
scleroderma spectrum disorder
MTX
methylaminopterin
CYC
cyclophosphamide
MMF
mycophenolate mofetil
ACE
angiotensin converting enzyme
NO
nitric oxide
Systemic sclerosis
Epigenetic mechanisms
Biomarker
Therapy
MMPs and ADAMTSs in intervertebral disc degeneration
期刊论文
Clinica Chimica Acta, 2015, 卷号: 448, 页码: 238-246
作者:
Wang, Wen-Jun*
;
Yu, Xiao-Hua
;
Wang, Cheng
;
Yang, Wei
;
He, Wen-Si
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/27
IVD
intervertebral disc
IDD
intervertebral disc degeneration
ECM
extracellular matrix
MMPs
matrix metalloproteinases
ADAMTSs
a disintegrin and metalloprotease with thrombospondin motifs
NP
nucleus pulposus
AF
annulus fibrosus
Col I
type I collagen
Col II
type II collagen
IL-1
interleukin-1
MAPK
mitogen-activated protein kinase
MRI
magnetic resonance imaging
TIMP
tissue inhibitor of metalloproteinase
NGF
nerve growth factor
BMP
bone morphogenetic protein
TGF-β1
transforming growth factor-β1
SNPs
single nucleotide polymorphisms, miRNAs, microRNAs
LPS
lipopolysaccharide
TNF-α
tumor necrosis factor-α
NF-κB
nuclear factor κB
NO
nitric oxide
SDC4
syndecan-4
RSV
resveratrol
LfcinB
bovine lactoferricin
HO-1
heme oxygenase-1
MSCs
mesenchymal stem cells
IDD
MMPs
ADAMTSs
Col II
Aggrecan
©版权所有 ©2017 CSpace - Powered by
CSpace