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科研机构
北京大学 [2]
大连理工大学 [1]
上海神经科学研究所 [1]
上海药物研究所 [1]
水生生物研究所 [1]
山东大学 [1]
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期刊论文 [13]
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2020 [1]
2019 [1]
2018 [2]
2016 [2]
2015 [2]
2012 [2]
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BBB-penetrating codelivery liposomes treat brain metastasis of non-small cell lung cancer with EGFR(T790M) mutation
期刊论文
THERANOSTICS, 2020, 卷号: 10, 期号: 14, 页码: 6122-6135
作者:
Yin, Weimin
;
Zhao, Yuge
;
Kang, Xuejia
;
Zhao, Pengfei
;
Zhao, Xuhong
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/07/01
brain targeting delivery
tumor-associated macrophage
non-small cell lung cancer (NSCLC)
drug resistance
tyrosine kinase inhibitors (TKI)
EGFR T790M mutation
Evaluation of the combination mode and features of p38 MAPK inhibitors: construction of different pharmacophore models and molecular docking
期刊论文
MOLECULAR SIMULATION, 2019, 卷号: 45, 期号: 12, 页码: 975-984
作者:
Sun, Bin
;
Zhang, Hong
;
Dong, Yue
;
Zhao, Liyu
;
Han, Jun
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/11
p38 MAPK inhibitors
targeting kinase
pharmacophore model
molecular
docking
The long noncoding RNA lncZic2 drives the self-renewal of liver tumor-initiating cells via the protein kinase C substrates MARCKS and MARCKSL1
期刊论文
Journal of Biological Chemistry, 2018, 卷号: 293, 期号: 21, 页码: 7982-7992
作者:
Chen, Zhenzhen
;
Liu, Yating
;
Yao, Lintong
;
Guo, Shiying
;
Gao, Yanfeng*
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/04
*Zic family member 2
*cancer stem cells
*chromatin regulation
*liver cancer
*long noncoding RNA (long ncRNA, lncRNA)
*myristoylated alanine-rich protein kinase C substrate
*protein kinase C signaling
*self-renewal
*tumor promoter
*tumor targeting
*tumor therapy
Highly Selective Red-Emitting Fluorescent Probe for Imaging Cancer Cells in Situ by Targeting Pim-1 Kinase
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2018, 卷号: 10, 页码: 1499-1507
作者:
Guo, Shigang
;
Fan, Jiangli
;
Wang, Benhua
;
Xiao, Ming
;
Li, Yueqing
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/02
Pim-1 kinase
biomarkei-targeting
cancer cell imaging mitochondria localization
in vivo imaging
Salt-inducible Kinase (SIK1) regulates HCC progression and WNT/β-catenin activation
期刊论文
Journal of Hepatology, 2016, 卷号: 64, 期号: 5, 页码: 1076-1089
作者:
Qu, Chao
;
He, De
;
Lu, Xiaoling
;
Dong, Lihua
;
Zhu, Yuekun
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/03
ChIP
chromatin immunoprecipitation
DFS
disease-free survival
EGF
epidermal growth factor
EMT
epithelial-mesenchymal transition
GSK-3β
glycogen synthase kinase-3β
HCC
hepatocellular carcinoma
HDAC3
histone deacetylase 3
IF
immunofluorescence
IHC
immunohistochemistry
NCoR
nuclear receptor corepressor
OS
overall survival
PCR
polymerase chain reaction
TBL1
transducin-beta-like protein 1
TBLR1
transducing-beta-like 1 X-linked receptor 1
TF
transcriptional factor
shSIK1
small hairpin RNA targeting SIK1
Salt-inducible kinase 1
Twist1
Epithelial-mesenchymal transition
β-catenin
Silencing mediator for retinoid
Thyroid receptors
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
期刊论文
AUTOPHAGY, 2016
Klionsky, Daniel J.
;
Abdelmohsen, Kotb
;
Abe, Akihisa
;
Abedin, Md Joynal
;
Abeliovich, Hagai
;
Arozena, Abraham Acevedo
;
Adachi, Hiroaki
;
Adams, Christopher M.
;
Adams, Peter D.
;
Adeli, Khosrow
;
Adhihetty, Peter J.
;
Adler, Sharon G.
;
Agam, Galila
;
Agarwal, Rajesh
;
Aghi, Manish K.
;
Agnello, Maria
;
Agostinis, Patrizia
;
Aguilar, Patricia V.
;
Aguirre-Ghiso, Julio
;
Airoldi, Edoardo M.
;
Ait-Si-Ali, Slimane
;
Akematsu, Takahiko
;
Akporiaye, Emmanuel T.
;
Al-Rubeai, Mohamed
;
Albaiceta, Guillermo M.
;
Albanese, Chris
;
Albani, Diego
;
Albert, Matthew L
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2017/12/03
autolysosome
autophagosome
chaperone-mediated autophagy
flux
LC3
lysosome
macroautophagy
phagophore
stress
vacuole
CHAPERONE-MEDIATED AUTOPHAGY
ACTIVATED PROTEIN-KINASE
PROGRAMMED CELL-DEATH
STARVATION-INDUCED AUTOPHAGY
ENDOPLASMIC-RETICULUM STRESS
NF-KAPPA-B
VACUOLE TARGETING PATHWAY
ISOLATED RAT HEPATOCYTES
YEAST SACCHAROMYCES-CEREVISIAE
GLUCAGON-INDUCED AUTOPHAGY
Modeling the mitotic regulatory network identifies highly efficient anti-cancer drug combinations
期刊论文
分子生物系统, 2015
Wu, Yiran
;
Zhuo, Xiaolong
;
Dai, Ziwei
;
Guo, Xiao
;
Wang, Yao
;
Zhang, Chuanmao
;
Lai, Luhua
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/10
SPINDLE-ASSEMBLY CHECKPOINT
CELL-CYCLE OSCILLATOR
AURORA-A KINASE
UBIQUITIN-CONJUGATING ENZYME
POLO-LIKE KINASES
IN-SILICO
TARGETING MITOSIS
SYSTEMS BIOLOGY
B KINASE
CANCER
Re-expression of LKB1 in LKB1-mutant EKVX cells leads to resistance to paclitaxel through the up-regulation of MDR1 expression
期刊论文
LUNG CANCER, 2015, 卷号: 88, 页码: 131-138
作者:
Mao, Kaisheng[1,2,3,4]
;
Liu, Fakeng[1,4]
;
Liu, Xiuju[1]
;
Khuri, Fadlo R.[1]
;
Marcus, Adam I.[1]
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/04/25
Microtubule targeting agents
Paclitaxel resistance
Tumor suppressor
Promoter methylation
Multi-drug resistance
Serine/threonine kinase
Guidelines for the use and interpretation of assays for monitoring autophagy
期刊论文
AUTOPHAGY, 2012, 卷号: 8, 期号: 4, 页码: 445-544
作者:
Zhang, Ming-Yong#
;
MORE-Author*
;
Klionsky, Daniel J.
收藏
  |  
浏览/下载:99/0
  |  
提交时间:2018/12/18
Autolysosome
Activated Protein-kinase
Chaperone-mediated Autophagy
Programmed Cell-death
Isolated Rat Hepatocytes
Starvation-induced Autophagy
Vacuole Targeting Pathway
Glucagon-induced Autophagy
Breast-cancer Cells
Betaine Homocysteine Methyltransferase
Endoplasmic-reticulum Stress
Autophagosome
Flux
Lc3
Phagophore
Lysosome
Stress
Vacuole
Targeted inhibition of renal Rho kinase reduces macrophage infiltration and lymphangiogenesis in acute renal allograft rejection
期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2012, 卷号: 694, 期号: 1-3
作者:
Poosti, Fariba
;
Yazdani, Saleh
;
Dolman, M. Emmy M.
;
Kok, Robbert Jan
;
Chen, Cheng
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
Rho kinase
Drug targeting
Kidney transplantation
Lymphangiogenesis
Macrophage
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