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Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine
期刊论文
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:
Xue, Yaru
;
Ren, Xuelian
;
Zhu, Zhengdan
;
Lei, Peng
;
Liu, Mengling
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/01/18
3-n-butylphthalide
Hepatotoxicity
Oxidative stresses
Covalent protein modification
Drug-drug interaction
Nano-selenium attenuates mitochondrial-associated apoptosis via the PI3K/AKT pathway in nickel-induced hepatotoxicity in vivo and in vitro
期刊论文
ENVIRONMENTAL TOXICOLOGY, 2021
作者:
Wang, Caixia
;
Gu, Zhangyu
;
Gu, Xueyan
;
Tan, Xinyue
;
Wang, Shuang
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2021/11/01
hepatotoxicity
mitochondrial apoptosis
Nano-Se
nickel
PI3K-Akt pathway
Chronic exposure to PPCPs mixture at environmentally relevant concentrations (ERCs) altered carbohydrate and lipid metabolism through gut and liver toxicity in zebrafish
期刊论文
ENVIRONMENTAL POLLUTION, 2021, 卷号: 273, 页码: 10
作者:
Hamid, Naima
;
Junaid, Muhammad
;
Wang, Yan
;
Pu, Shi-Ya
;
Jia, Pan-Pan
收藏
  |  
浏览/下载:90/0
  |  
提交时间:2021/05/17
Hepatotoxicity
Gut homeostasis
Chronic exposure
Lipid metabolism
Zebrafish
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP)
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
作者:
Wang, Xiaoqing
;
Li, Fei
;
Liu, Jialin
;
Ji, Chenglong
;
Wu, Huifeng
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2021/06/21
Triphenyl phosphate (TPP)
Multi-omit approach
Hepatotoxicity
Tetrabromobisphenol A (TBBPA): A controversial environmental pollutant
期刊论文
JOURNAL OF ENVIRONMENTAL SCIENCES, 2020, 卷号: 97, 页码: 54-66
作者:
Zhou, Hui
;
Yin, Nuoya
;
Faiola, Francesco
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  |  
浏览/下载:29/0
  |  
提交时间:2021/09/14
Tetrabromobisphenol A (TBBPA)
Developmental toxicity
Endocrine disrupting chemicals(EDC)
Hepatotoxicity
Neurotoxicity
Protein target identification and toxicological mechanism investigation of silver nanoparticles-induced hepatotoxicity by integrating proteomic and metallomic strategies
期刊论文
PARTICLE AND FIBRE TOXICOLOGY, 2019, 卷号: 16, 期号: 1, 页码: -
作者:
Xu, Ming
;
Yang, Qiuyuan
;
Xu, Lining
;
Rao, Ziyu
;
Cao, Dong
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/09/10
Silver nanoparticles
Silver ion
Hepatotoxicity
Protein target
Glutathione S-transferase
Establishment of a human embryonic stem cell-based liver differentiation model for hepatotoxicity evaluations
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 174, 页码: 353-362
作者:
Liang, Shengxian
;
Liang, Shaojun
;
Yin, Nuoya
;
Faiola, Francesco
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/10/21
Thyroid hormones (THs)
Polybrominated diphenyl ethers BDE-47/209
Human embryonic stem cells (ESCs)
Developmental hepatotoxicity
Endocrine-disrupting chemicals (EDCs)
A metabolomic perspective of pazopanib-induced acute hepatotoxicity in mice
期刊论文
XENOBIOTICA, 2019, 卷号: 49, 期号: 6, 页码: 655-670
作者:
Wang, Yi-Kun
;
Yang, Xiao-Nan
;
Liang, Wei-Qing
;
Xiao, Yao
;
Zhao, Qi
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2019/07/29
Pazopanib
hepatotoxicity
metabolomics
oxidative stress
ultra-performance liquid chromatography-electrospray ion source-quadrupole
time-of-flight mass spectrometer (UPLC-ESI-QTOFMS)
Distribution, metabolism and hepatotoxicity of neonicotinoids in small farmland lizard and their effects on GH/IGF axis
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2019, 卷号: 662, 页码: 834-841
作者:
Wang, Yinghuan
;
Zhang, Yang
;
Li, Wei
;
Yang, Lu
;
Guo, Baoyuan
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/10/23
Attenuation
Eremias argus
Neonicotinoids
Hepatotoxicity
GH/IGF
Rapid Discovery of the Potential Toxic Compounds in Polygonum multiflorum by UHPLC/Q-Orbitrap-MS-Based Metabolomics and Correlation Analysis
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 12
作者:
Liu, Caixiang
;
Hu, Limin
;
Yang, Wenzhi
;
Dou, Zhiying
;
Zheng, Fang
收藏
  |  
浏览/下载:77/0
  |  
提交时间:2019/06/24
Polygonum multiflorum
metabolomics
hepatotoxicity
L02 cell
UHPLC/Q-Orbitrap-MS
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