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科研机构
复旦大学上海医学院 [5]
上海药物研究所 [3]
山东大学 [2]
内容类型
期刊论文 [10]
发表日期
2019 [2]
2018 [3]
2017 [4]
2016 [1]
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Synthesis and biological evaluation of anthraquinone derivatives as allosteric phosphoglycerate mutase 1 inhibitors for cancer treatment
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 168
作者:
Huang, Ke
;
Jiang, Lulu
;
Liang, Ronghui
;
Li, Huiti
;
Ruan, Xiaoxue
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Phosphoglycerate mutase 1
Anthraquinone derivatives
Allosteric inhibitors
Cancer treatment
Development of Anthraquinone Analogues as Phosphoglycerate Mutase 1 Inhibitors
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 5
作者:
Huang, Ke
;
Jiang, Lulu
;
Li, Huiti
;
Ye, Deyong
;
Zhou, Lu
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
phosphoglycerate mutase 1
anthraquinone inhibitors
co-crystal structure
cancer treatment
Xanthone derivatives as phosphoglycerate mutase 1 inhibitors: Design, synthesis, and biological evaluation
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8
作者:
Zhang, Shiyu
;
Wang, Penghui
;
Jiang, Lulu
;
Cao, Yang
;
Zhang, Xiaodan
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Phosphoglycerate mutase 1
Inhibitors
Xanthone derivatives
Cancer cell metabolism
The Design and Synthesis of N-Xanthone Benzenesulfonamides as Novel Phosphoglycerate Mutase 1 (PGAM1) Inhibitors
期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 6
作者:
Zhou, Lu
;
Wang, Penghui
;
Jiang, Lulu
;
Cao, Yang
;
Ye, Deyong
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/12/05
phosphoglycerate mutase 1
inhibitors
anti-cancer
xanthone
Phosphoglycerate mutase 1 is highly expressed in C6 glioma cells and human astrocytoma
期刊论文
ONCOLOGY LETTERS, 2018, 卷号: 15, 期号: 6, 页码: 8935-8940
作者:
Liu, Zhi-Guo
;
Ding, Jie
;
Du, Chuan
;
Xu, Ning
;
Wang, En-Le
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/11
phosphoglycerate mutase 1
glioma
astrocytoma
semi-quantitative
reverse transcription polymerase chain reaction
immunohistochemistry
Conformation and dynamics of the C-terminal region in human phosphoglycerate mutase 1
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 12, 页码: 1673-1682
作者:
Liu, Shi-en
;
Hu, Jun-chi
;
Zhang, Hao
;
Xu, Pan
;
Wan, Wei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
phosphoglycerate mutase 1 (PGAM1)
human cancers
metabolic target
C-terminal region
conformational changes
molecular dynamics simulation
Identification of Epigallocatechin-3-Gallate as an Inhibitor of Phosphoglycerate Mutase 1
期刊论文
FRONTIERS IN PHARMACOLOGY, 2017, 卷号: 8
作者:
Li, Xiaoguang
;
Tang, Shuai
;
Wang, Qian-Qian
;
Leung, Elaine L. -H.
;
Jin, Hongyue
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
phosphoglycerate mutase 1 (PGAM1)
inhibitor
cancer metabolism
natural products
anticancer activity
Conformation and dynamics of the C-terminal region in human phosphoglycerate mutase 1
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 12
作者:
Liu, Shi-en
;
Hu, Jun-chi
;
Zhang, Hao
;
Xu, Pan
;
Wan, Wei
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
phosphoglycerate mutase 1 (PGAM1)
human cancers
metabolic target
C-terminal region
conformational changes
molecular dynamics simulation
Phosphoglycerate Mutase 1 Predicts the Poor Prognosis of Oral Squamous Cell Carcinoma and is Associated with Cell Migration
期刊论文
JOURNAL OF CANCER, 2017, 卷号: 8, 期号: 11, 页码: 1943-1951
作者:
Zhang, Dadong
;
Wu, Heming
;
Zhang, Xiaomin
;
Ding, Xu
;
Huang, Min
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/01/08
Oral cancer
Phosphoglycerate mutase 1
Migration
Prognosis
SRC
The diagnostic value and functional roles of phosphoglycerate mutase 1 in glioma
期刊论文
ONCOLOGY REPORTS, 2016, 卷号: 36, 期号: 4, 页码: 2236-2244
作者:
Xu, Zhenkuan
;
Gong, Jie
;
Wang, Chuanwei
;
Wang, Yunyan
;
Song, Yan
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/16
phosphoglycerate mutase 1
glioma
proliferation
migration
invasion
apoptosis
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