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Engineering Enzyme-Cleavable Oligonucleotides by Automated Solid-Phase Incorporation of Cathepsin B Sensitive Dipeptide Linkers
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022
作者:
Jin, Cheng
;
Ei-Sagheer, Afaf H.
;
Li, Siqi
;
Vallis, Katherine A.
;
Tan, Weihong
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2022/03/21
Cathepsin B
DNA Breakage
Dipeptide Linker
Oligonucleotide-Drug Conjugates
Solid-Phase Synthesis
Divalent tranylcypromine derivative as lysine-specific demethylase 1 inhibitor
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2021, 页码: 8
作者:
Sun, Yin
;
Li, Na
;
Su, Mingbo
;
Wang, Xiaowen
;
Zhao, Dongmei
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2021/05/24
Divalent tranylcypromine
LSD1 inhibitor
MV4-11 antiproliferative activity
CD86 mRNA expression
Linker
Selectivity
Conjugation of staphylokinase with the arabinogalactan-PEG conjugate: Study on the immunogenicity, in vitro bioactivity and pharmacokinetics
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 卷号: 131, 页码: 896-904
作者:
Qi, Fangbing
;
Qi, Jinming
;
Hu, Chunyang
;
Shen, Lijuan
;
Yu, Weili
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2019/06/14
Staphylokinase
Arabinogalactan
Immunogenicity
Pharmacokinetic
PEG linker
in vitro activity
Palladium-Catalyzed Propargylic [n+2] Cycloaddition: An Efficient Strategy for Construction of Benzo-Fused Medium-Sized Heterocycles
期刊论文
ADVANCED SYNTHESIS & CATALYSIS, 2019, 卷号: 361, 期号: 4, 页码: 836-841
作者:
Liu, Zhen-Ting
;
Hu, Xiang-Ping
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2019/06/20
A regioselective palladium-catalyzed formal [n+2] cycloaddition of propargylic esters as C-2-synthons with various linker-tethered bisphenols for the construction of medium-sized heterocycles bearing an exocyclic double bond has been developed
The reaction features mild conditions and broad substrate scopes
as well as readily available substrates and catalysts
Under optimal conditions
various medium-sized heterocycles from eight to eleven-membered rings can be afforded in good to excellent yields and regioselectivities with high Z-selectivity for the exocyclic double bond
palladium
medium-sized ring
propargylic ester
bisphenol
cycloaddition
Palladium-catalyzed propargylic [n+2] cycloaddition: an efficient strategy for construction of benzo-fused medium-sized heterocycles
期刊论文
Advanced synthesis & catalysis, 2019, 卷号: 361, 期号: 4, 页码: 836-841
作者:
Liu, Zhen-Ting
;
Hu, Xiang-Ping
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2019/05/08
A regioselective palladium-catalyzed formal [n+2] cycloaddition of propargylic esters as c-2-synthons with various linker-tethered bisphenols for the construction of medium-sized heterocycles bearing an exocyclic double bond has been developed
The reaction features mild conditions and broad substrate scopes
As well as readily available substrates and catalysts
Under optimal conditions
Various medium-sized heterocycles from eight to eleven-membered rings can be afforded in good to excellent yields and regioselectivities with high z-selectivity for the exocyclic double bond
Palladium
Medium-sized ring
Propargylic ester
Bisphenol
Cycloaddition
LncRNA AY promotes hepatocellular carcinoma metastasis by stimulating ITGAV transcription
期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 15
作者:
Kang, Chun Lan
;
Qi, Bing
;
Cai, Qian Qian
;
Fu, Li Sheng
;
Yang, Ying
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/12/05
metastasis
integrin
migration
linker histone
epigenetics
UV–Vis absorption studies of coordination-driven self-assembled 2D metalla-rectangle towards multi-carboxylation anions
期刊论文
Polyhedron, 2019, 卷号: 157, 页码: 262-266
作者:
Vardhan, Harsh
;
Verpoort, Francis*
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/04
Amide linker
Ruthenium complex
Self-assembly
Metalla-rectangle
Multi-carboxylate anions
Fabrication and orientation of Ni-LAB membranes by linker salt approach
期刊论文
MICROPOROUS AND MESOPOROUS MATERIALS, 2019, 卷号: 287, 页码: 135-143
作者:
Cheng, Linjuan
;
Yang, Jianhua
;
Saulat, Hammad
;
Li, Liangqing
;
Lu, Jinming
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/02
Ni-LAB membrane
Linker salt method
Solubility
High supersaturation
Membrane orientation
pSBMA-Conjugated Magnetic Nanoparticles for Selective IgG Separation
期刊论文
LANGMUIR, 2019, 卷号: 35, 页码: 1111-1118
作者:
Cheng, Fang
;
Zhu, Chuanlei
;
He, Wei
;
Zhao, Jing
;
Qu, Jingping
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/02
Body fluids
Nanoparticles, Biological fluids
Divinyl sulfone
Linker molecules
Magnetic nano-particles
One-step methods
Short chain lengths
Three orders of magnitude
Zwitterionic polymers, Nanomagnetics
Effect of Cross-Linker with Different Si-H Contents on the Properties of Silicone Elastomers
期刊论文
Journal of Tianjin University Science and Technology, 2019, 卷号: Vol.52 No.7, 页码: 763-769
作者:
Feng, Y.
;
Meng, F.
;
Zhao, J.
;
Shen, J.
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/11/21
Cross-linker
Mechanical property
Oil bleeding
Si-H content
Surface stickiness
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