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Evaluation of selected traditional Chinese medical extracts for bone mineral density maintenance: A mechanistic study. 期刊论文
Journal of traditional and complementary medicine, 2019, 卷号: 9, 期号: 3
作者:  Rebhun John F;  Du Qin;  Hood Molly;  Guo Hailing;  Glynn Kelly M
收藏  |  浏览/下载：45/0  |  提交时间：2019/12/05
Anti-inflammatory  BMD, bone mineral density  BSA, bovine serum albumin  Bmp4, bone morphogenic protein 4  CRE, cyclic adenosine monophosphate response element  CREB, cyclic adenosine monophosphate response element binding protein  DEXA, dual-energy X-ray absorptiometry  DMSO, Dimethyl sulfoxide  Drynaria fortunei  E2, estradiol  ER, estrogen receptor  ERE, estrogen response element  Epimedium brevicornu  Estrogenic  FBS, fetal bovine serum  Fsk, forskolin  Hprt, hypoxanthine-guanine phosphoribosyl-transferase  IL-1, interleukin 1  LBD, ligand binding domain  LBM, low bone mass  M-CSF, macrophage colony-stimulating factor  MAPK, mitogen activated protein kinase  NF-κβ, nuclear factor kappa beta  OP, osteoporosis  Osteoporosis  PTH, parathyroid hormone  PTHrp, PTH related peptide  RANKL, receptor activator of nuclear factor kappa beta ligand  RLU, relative luminescence unit  ROI, region of interest  Runx2, runt-related transcription factor 2  SFM, serum free media  TCM, traditional Chinese medicine  TNFα, tumor necrosis factor alpha  TRAP, tartrate-resistant acid phosphatase  UAS, upstream activating sequence  cAMP, cyclic adenosine monophosphate  qPCR, quantitative polymerase chain reaction  
Beta-hydroxybutyrate Promotes the Expression of BDNF in Hippocampal Neurons under Adequate Glucose Supply 期刊论文
NEUROSCIENCE, 2018, 卷号: 386, 页码: 315-325
作者:  Hu Erling;  Du Huan;  Zhu Xinliang;  Wang Leilei;  Shang Sen
收藏  |  浏览/下载：3/0  |  提交时间：2019/11/26
Autophagy induces transforming growth factor--dependent epithelial-mesenchymal transition in hepatocarcinoma cells through cAMP response element binding signalling 期刊论文
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2018, 卷号: Vol.22 No.11, 页码: 5518-5532
作者:  Hu, Shaobo;  Wang, Liyu;  Zhang, Xi;  Wu, Yongzhong;  Yang, Jing
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/26
The Hippocampus is a Critical Site Mediating Antidepressant-like Activity of Apelin-13 in Rats 期刊论文
Neuroscience, 2018, 卷号: 375, 页码: 1-9
作者:  Xiao, Zhi-Yong;  Wang, Bo;  Fu, Wan;  Jin, Xin;  You, Yong
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/27
Combination of metformin with chemotherapeutic drugs via different molecular mechanisms 期刊论文
Cancer Treatment Reviews, 2017, 卷号: 54, 页码: 24-33
作者:  Peng, Mei*;  Darko, Kwame Oteng;  Tao, Ting;  Huang, Yanjun;  Su, Qiongli
收藏  |  浏览/下载：14/0  |  提交时间：2019/12/03
AIs  aromatase inhibitors  AMPK  Adenosine Monophosphate-Activated Protein Kinase  AR  androgen  ATM  Ataxia Telangiectasia Mutated  ATP  Adenosine Triphosphate  BCSS  breast cancer specific survival  CK-MB  Creatine Kinase-MB  CREB1  cAMP Response Element-Binding Protein 1  CSC  cancer stem cell  DFS  disease-free survival  DHFU  dihydrofluorouracil  DPD  dihydropyrimidine dehydrogenase  EpCAM  Epithelial Cell Adhesion Molecule  ER  estrogen  ERCC1  excision repair cross-complementary 1  ERK  extracellular signal-regulated kinases  EZH2  enhancer of zeste homolog 2  FdUMP  fluorodeoxyuridine monophosphate  FdUTP  fluorodeoxyuridine triphosphate  FHC  ferritin heavy chain  FUTP  fluorouridine triphosphate  HbA1C  hemoglobin A1c  HER  Human Epidermal Growth Factor Receptor  HIF-1α  hypoxia-inducible factor-1α  HK  hexokinase  IGF1R  insulin growth factor 1 receptor  LDH  lactate dehydrogenase  MDA  Muscular Dystrophy Association  MMP  Matrix Metallopeptidase  MRP1  multidrug resistance-associated protein 1  mTOR  mammalian target of rapamycin  MTX  methotrexate  NCCN  National Comprehensive Cancer Network  OS  overall survival  pCR  Pathologic Complete Response  PDGFR  platelet-derived growth factor receptors  PFS  progression-free survival  PKA  protein kinase A  PR  progesterone receptor  RFS  relapse-free survival  SOD  superoxide dismutase  TAM  tamoxifen  TCA  tricarboxlic acid  TS  thymidylate synthase  Combination  Mechanisms  Metformin  Chemotherapeutic drugs  
Expression of Iron Regulatory Protein 1 Is Regulated not only by HIF-1 but also pCREB under Hypoxia 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2016, 卷号: 12, 期号: 10
作者:  Luo, Qian-Qian;  Qian, Zhong-Ming;  Zhou, Yu-Fu;  Zhang, Meng-Wan;  Wang, Dang
收藏  |  浏览/下载：10/0  |  提交时间：2019/12/05
Time-dependent co-relation of BDNF and CREB mRNAs in adult rat brains following acute psychological stress in the communication box paradigm 期刊论文
Neuroscience Letters, 2016, 卷号: 624, 页码: 34-41
作者:  Li, Gongying;  Wang, Yanmei;  Yan, Min;  Ma, Hongxia;  Gao, Yanjie
收藏  |  浏览/下载：7/0  |  提交时间：2019/12/03
Understanding the CREB1-miRNA feedback loop in human malignancies 期刊论文
TUMOR BIOLOGY, 2016, 卷号: 37, 期号: 7, 页码: 8487-8502
作者:  Wang, Ya-Wen;  Chen, Xu;  Ma, Rong;  Gao, Peng
收藏  |  浏览/下载：1/0  |  提交时间：2019/12/16
The anti-dementia drug candidate, (-)-clausenamide, improves memory impairment through its multi-target effect 期刊论文
Pharmacology and Therapeutics, 2016, 卷号: 162, 页码: 179-187
作者:  Chu, Shifeng;  Liu, Shaolin;  Duan, Wenzhen;  Cheng, Yong;  Jiang, Xueying
收藏  |  浏览/下载：8/0  |  提交时间：2019/12/27
Chirality  Clausenamide  Dementia  Long-term potentiation  Signaling pathway  Calcium  6-OHDA  6-hydroxyldopamine  ACE  acetylcholinesterase  ACh  acetylcholine  AD  Alzheimer's disease  AUC0–12 h  0–12 h area under curve  APP  amyloid precursor protein  APV  R-2-amino-5-phosphonopentanoate  AUC0−∝  whole area under curve  BBB  blood–brain barrier  BDNF  brain-derived neurotrophic factor  CaM  calmodulin  CaMKII  calmodulin kinase II  ChAT  choline acetyltransferase  CREB  cAMP responding element binding  CHM  Chinese herbal medicine  clau  clausenamide  CL  clearance  Cmax  maximum concentration  CDK-5  cyclin-dependent kinase-5  DM  diabetes mellitus  DAG  diacylglycerol  ER  endoplasmic reticulum  ERK  extracellular signal-regulated kinases  GSK-3  glycogen synthase kinase-3  IP3  inositol triphosphate  LTP  long term potentiation  MWM  Morris water maze  NGF  nerve growth factor  NMDA  N-Methyl-D-aspartate  D  nNOS  neural nitric oxide synthase  PAT  passive avoidance tasks  Pir  piracetam  PLC  phospholipase C  PP1  phosphate 1  PKC  protein kinase C  tmax  time of peak concentration  t1/2α  absorption half-life  t1/2β  elimination half-life  Tau  microtubule-associated proteins  TCM  traditional Chinese medicine  Vd  apparent volume of distribution  VDCC  voltage-dependent calcium channel  
Cilostazol promotes production of melanin by activating the microphthalmia-associated transcription factor (MITF) 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2014, 卷号: 443, 页码: 617-621
作者:  Wei, Bo[1];  Zhang, Yu-Pei[1];  Yan, Hai-Zhen[1];  Xu, Yi[2];  Du, Tian-Min[2]
收藏  |  浏览/下载：4/0  |  提交时间：2019/04/25

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