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复旦大学上海医学院 [21]
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Clinical outcomes of lung adenocarcinoma patients harboring uncommon epidermal growth factor receptor (EGFR) mutations treated with EGFR-tyrosine kinase inhibitors (TKIs)
期刊论文
ANNALS OF PALLIATIVE MEDICINE, 2021
作者:
Si, Jinfei
;
Gu, Xiaodong
;
Wang, Wenxian
;
Ying, Shenpeng
;
Song, Zhengbo
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2022/02/14
Epidermal growth factor receptor (EGFR)
uncommon mutation
compound mutation
double uncommon mutation
lung adenocarcinoma (lung AC)
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
MD2 blockage prevents the migration and invasion of hepatocellular carcinoma cells via inhibition of the EGFR signaling pathway
期刊论文
JOURNAL OF GASTROINTESTINAL ONCOLOGY, 2021
作者:
Qi, Yajun
;
Fang, Qilu
;
Li, Qinglin
;
Ding, Haiying
;
Shu, Qi
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/09/06
Hepatocellular carcinoma (HCC)
myeloid differentiation protein 2 (MD2)
epidermal growth factor receptor (EGFR)
migration
invasion
Tumor Mutation Burden Correlates With Efficacy of Chemotherapy/Targeted Therapy in Advanced Non-Small Cell Lung Cancer
期刊论文
FRONTIERS IN ONCOLOGY, 2020, 卷号: 10
作者:
Lin, Chen
;
Shi, Xun
;
Zhao, Jun
;
He, Qiong
;
Fan, Yun
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/10/26
tumor mutation burden (TMB)
clinical benefit
epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs)
chemotherapy
non-small cell lung cancer (NSCLC)
Design and synthesis of selective degraders of EGFR(L858R/T790M) mutant
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 192, 页码: 14
作者:
Zhang, Xin
;
Xu, Fang
;
Tong, Linjiang
;
Zhang, Tao
;
Xie, Hua
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2020/07/01
Epidermal growth factor receptor (EGFR)
Resistance
Proteolysis targeting chimera (PROTAC)
Protein degradation
LRG-1 promotes pancreatic cancer growth and metastasis via modulation of the EGFR/p38 signaling
期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2019, 卷号: 38
作者:
Xie, Zhi-Bo
;
Zhang, Yi-Fan
;
Jin, Chen
;
Mao, Yi-Shen
;
Fu, De-Liang
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
LRG-1
Pancreatic ductal adenocarcinoma
Epidermal growth factor receptor (EGFR)
p38
Biomarker
Prediction of EGFR Mutations by Conventional CT-Features in Advanced Pulmonary Adenocarcinoma
期刊论文
European Journal of Radiology, 2019
作者:
Yanqing Chen
;
Yang Yang
;
Longbai Ma
;
Huiyuan Zhu
;
Tienan Feng
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2019/12/13
Computed
tomography
(CT)
Epidermal
growth
factor
receptor
(EGFR)
mutations
Advanced
pulmonary
adenocarcinoma
A low-molecular-weight compound exerts anticancer activity against breast and lung cancers by disrupting EGFR/Eps8 complex formation
期刊论文
Journal of Experimental & Clinical Cancer Research, 2019, 卷号: Vol.38 No.1
作者:
Meifang Li
;
Jilong Yang
;
Lenghe Zhang
;
Sanfang Tu
;
Xuan Zhou
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/13
Epidermal growth factor receptor (EGFR)
Epidermal growth factor receptor pathway substrate 8 (Eps8)
Breast cancer
NSCLC, small-molecule inhibitor
A low-molecular-weight compound exerts anticancer activity against breast and lung cancers by disrupting EGFR/Eps8 complex formation.
期刊论文
Journal of Experimental & Clinical Cancer Research, 2019, 卷号: Vol.38 No.1
作者:
Li, Meifang
;
Yang, Jilong
;
Zhang, Lenghe
;
Tu, Sanfang
;
Zhou, Xuan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/12/13
Breast cancer
Epidermal growth factor receptor (EGFR)
Epidermal growth factor receptor pathway substrate 8 (Eps8)
NSCLC, small-molecule inhibitor
Identifying EGFR mutations in lung adenocarcinoma by noninvasive imaging using radiomics features and random forest modeling.
期刊论文
European radiology, 2019
作者:
Tian-Ying Jia
;
Jun-Feng Xiong
;
Xiao-Yang Li
;
Wen Yu
;
Zhi-Yong Xu
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/13
Epidermal
growth
factor
receptor
(EGFR)
Non-small
cell
lung
cancer
(NSCLC)
Radiomics
Random
forest
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