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科研机构
中国医学科学院 北京... [7]
上海药物研究所 [4]
金属研究所 [2]
四川大学 [1]
合肥物质科学研究院 [1]
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期刊论文 [15]
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2022 [1]
2020 [2]
2019 [1]
2018 [5]
2017 [6]
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Impact of clinical and molecular features on efficacy and outcome of patients with non-small cell lung cancer receiving second-line osimertinib
期刊论文
BMC CANCER, 2022, 卷号: 22
作者:
Jin, Ying
;
Lin, Chen
;
Shi, Xun
;
He, Qiong
;
Yan, Junrong
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/12/23
Clinical and molecular features
Efficacy and outcome
EGFR T790M mutation
Non-small-cell lung cancer
Osimertinib
Safety, Clinical Activity, and Pharmacokinetics of Al flutinib (AST2818) in Patients With Advanced NSCLC With EGFR T790M Mutation
期刊论文
JOURNAL OF THORACIC ONCOLOGY, 2020, 卷号: 15, 期号: 6, 页码: 1015-1026
作者:
Shi, Yuankai
;
Zhang, Shucai
;
Hu, Xingsheng
;
Feng, Jifeng
;
Ma, Zhiyong
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/12/24
Alflutinib
NSCLC
EGFR T790M mutation
Efficacy
Safety
BBB-penetrating codelivery liposomes treat brain metastasis of non-small cell lung cancer with EGFR(T790M) mutation
期刊论文
THERANOSTICS, 2020, 卷号: 10, 期号: 14, 页码: 6122-6135
作者:
Yin, Weimin
;
Zhao, Yuge
;
Kang, Xuejia
;
Zhao, Pengfei
;
Zhao, Xuhong
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  |  
浏览/下载:44/0
  |  
提交时间:2020/07/01
brain targeting delivery
tumor-associated macrophage
non-small cell lung cancer (NSCLC)
drug resistance
tyrosine kinase inhibitors (TKI)
EGFR T790M mutation
Efficacy and Safety of Gefitinib as Third-line Treatment in NSCLC Patients With Activating EGFR Mutations Treated With First-line Gefitinib Followed by Second-line Chemotherapy A Single-Arm, Prospective, Multicenter Phase II Study (RE-CHALLENGE,
期刊论文
2019, 卷号: 42, 期号: 5, 页码: 432-439
作者:
Song, Yong
;
Wu, Yi-Long
;
Cao, Le-Jie
;
Chen, Jian-Hua
;
Ma, Zhi-Yong
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/01/03
re-challenge
gefitinib
T790M mutation
progression-free survival
EGFR-TKI
NSCLC
Remodeling Tumor-Associated Macrophages and Neovascularization Overcomes EGFR(T790M)-Associated Drug Resistance by PD-L1 Nanobody-Mediated Codelivery
期刊论文
SMALL, 2018, 卷号: 14, 期号: 47
作者:
Yin, Weimin
;
Yu, Xiaolu
;
Kang, Xuejia
;
Zhao, Yuge
;
Zhao, Pengfei
收藏
  |  
浏览/下载:100/0
  |  
提交时间:2019/01/08
antiangiogenesis
EGFR(T790M) mutation
PD-L1 nanobody
simvastatin
tumor-associated macrophage
YL143, a novel mutant selective irreversible EGFR inhibitor, overcomes EGFR(L858R, T790M)-mutant resistance in vitro and in vivo
期刊论文
CANCER MEDICINE, 2018, 卷号: 7, 期号: 4, 页码: 1430-1439
作者:
Zhang, Zhang
;
Zou, Jian
;
Yu, Lei
;
Luo, Jinfeng
;
Li, Yan
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2019/01/08
EGFR inhibitor
lung cancer
pharmacokinetic
selectively
T790M mutation
Re-biopsy status among Chinese non-small-cell lung cancer patients who progressed after icotinib therapy
期刊论文
2018, 卷号: 11, 页码: 7513-7519
作者:
Wang, Hanping
;
Zhang, Li
;
Si, Xiaoyan
;
Zhang, Xiaotong
;
Wang, Mengzhao
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/03
re-biopsy
T790M mutation
resistant mechanism
EGFR-TKI
icotinib
non-small-cell lung cancer
Penetration of the blood-brain barrier by avitinib and its control of intra/extra-cranial disease in non-small cell lung cancer harboring the T790M mutation
期刊论文
2018, 卷号: 122, 页码: 1-6
作者:
Wang Hanping
;
Zhang Li
;
Hu Pei
;
Zheng Xin
;
Si Xiaoyan
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/03
Brain metastases
Cerebrospinal fluid
Penetration rate
T790M mutation
Third generation EGFR TKI
Primary and acquired EGFR T790M-mutant NSCLC patients identified by routine mutation testing show different characteristics but may both respond to osimertinib treatment
期刊论文
2018, 卷号: 423, 页码: 9-15
作者:
Li, Weihua
;
Qiu, Tian
;
Guo, Lei
;
Ling, Yun
;
Gao, Yibo
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2020/01/03
Non-small cell lung cancer
Primary EGFR T790M mutation
Acquired EGFR T790M mutation
Sensitizing EGFR mutation
Mutant allele frequency
EGFR T790M ctDNA testing platforms and their role as companion diagnostics: Correlation with clinical outcomes to EGFR-TKIs
期刊论文
Cancer Letters, 2017, 卷号: Vol.403, 页码: 186-194
作者:
Liang, Z.
;
Cheng, Y.
;
Chen, Y.
;
Hu, Y.
;
Liu, W.-P.
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/02/25
Drug
resistance
EGFR
T790M
mutation
NSCLC
Tyrosine
kinase
inhibitors
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