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北京大学 [4]
上海药物研究所 [3]
理论物理研究所 [1]
武汉大学 [1]
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期刊论文 [9]
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New tanshinone I derivatives S222 and S439 similarly inhibit topoisomerase I/II but reveal different p53-dependency in inducing G2/M arrest and apoptosis
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 154, 页码: 255-264
作者:
Tian, Qian-Ting
;
Ding, Chun-Yong
;
Song, Shan-Shan
;
Wang, Ying-Qing
;
Zhang, Ao
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
Tanshinone-1
S222
S439
Anticancer targets
DNA topoisomerases
P53
Synthesis and antibacterial activity of C-2 or C-5 modified and D ring rejiggered canthin-6-one analogues
期刊论文
FOOD CHEMISTRY, 2018, 卷号: 253, 页码: 211-220
作者:
Dai, Jiangkun
;
Dan, Wenjia
;
Li, Nian
;
Wang, Ruixue
;
Zhang, Yao
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Synthesis
Canthin-6-one analogues
Antibacterial
Structure-activity relationships
Cell membrane
DNA topoisomerases
PJA1 Coordinates with the SMC5/6 Complex To Restrict DNA Viruses and Episomal Genes in an Interferon-Independent Manner
期刊论文
JOURNAL OF VIROLOGY, 2018, 卷号: 92, 期号: 22
作者:
Xu, Wei
;
Ma, Chunqiang
;
Zhang, Qi
;
Zhao, Rong
;
Hu, Dan
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
RING finger protein PJA1
SMC5/6 complex
DNA topoisomerases
hepatitis B virus
HBV
herpes simplex virus 1
HSV-1
episomal DNA
extrachromosomal DNA
host immune response
Topoisomerase 3 beta is the major topoisomerase for mRNAs and linked to neurodevelopment and mental dysfunction
期刊论文
NUCLEIC ACIDS RESEARCH, 2017
Ahmad, Muzammil
;
Shen, Weiping
;
Li, Wen
;
Xue, Yutong
;
Zou, Sige
;
Xu, Dongyi
;
Wang, Weidong
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2017/12/03
FRAGILE-X-SYNDROME
DNA TOPOISOMERASES
BINDING PROTEINS
III-BETA
SCHIZOPHRENIA
TOP3-BETA
FMRP
PERSPECTIVE
AUTISM
ROLES
Consistent rationalization of type-2 topoisomerases' unknotting, decatenating, supercoil-relaxing actions and their scaling relation
期刊论文
JOURNAL OF PHYSICS-CONDENSED MATTER, 2015
Liu, Zhirong
;
Chan, Hue Sun
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/12/03
wormlike DNA model
writhe
hooked-juxtaposition hypothesis
the bend-angle model
II DNA TOPOISOMERASES
NONEQUILIBRIUM TOPOLOGY SIMPLIFICATION
LOCAL JUXTAPOSITION GEOMETRY
ESCHERICHIA-COLI
CHIRAL DISCRIMINATION
STRUCTURAL BASIS
KNOTS
IV
MECHANISM
SELECTION
Local site preference rationalizes disentangling by DNA topoisomerases
期刊论文
physical review e, 2010
Liu, Zhirong
;
Zechiedrich, Lynn
;
Chan, Hue Sun
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  |  
浏览/下载:7/0
  |  
提交时间:2015/11/13
JUXTAPOSITION GEOMETRY
II TOPOISOMERASES
STRUCTURAL BASIS
CIRCULAR DNA
TOPOLOGY
KNOTS
SIMPLIFICATION
SIMULATIONS
MECHANISM
Action at Hooked or Twisted-Hooked DNA Juxtapositions Rationalizes Unlinking Preference of Type-2 Topoisomerases
期刊论文
分子生物学杂志, 2010
Liu, Zhirong
;
Zechiedrich, Lynn
;
Chan, Hue Sun
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2015/11/10
DNA supercoils
writhe
torsional energy
self-avoiding lattice polygons
Madras-Orlitsky-Shepp algorithm
INTERTWINED CATENATED DIMERS
SELF-AVOIDING WALKS
LATTICE MONTE-CARLO
ESCHERICHIA-COLI
II TOPOISOMERASES
THERMODYNAMIC PROPERTIES
TOPOLOGY SIMPLIFICATION
STATISTICAL-THEORY
SUPERCOILED DNA
WRITHING NUMBER
Elastic property of single double-stranded DNA molecules: Theoretical study and comparison with experiments
期刊论文
PHYSICAL REVIEW E, 2000, 卷号: 62, 期号: 1, 页码: 1045-1058
作者:
Zhou, HJ
;
Zhang, Y
;
Ou-Yang, ZC
;
Zhou, HJ , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China.
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浏览/下载:18/0
  |  
提交时间:2012/08/29
Supercoiled Dna
Entropic Elasticity
Stretching Dna
Model
Extension
Topoisomerases
Fluctuations
Stiffness
Filaments
Mechanism
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