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山东大学 [7]
北京大学 [6]
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厦门大学 [3]
上海药物研究所 [3]
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期刊论文 [31]
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Combating a Master Manipulator: Staphylococcus aureus Immunomodulatory Molecules as Targets for Combinatorial Drug Discovery
期刊论文
ACS Combinatorial Science, 2018, 卷号: 20, 期号: 12, 页码: 681-693
作者:
Rakesh, Kadalipura P.
;
Marichannegowda, Manukumar H.*
;
Srivastava, Shobhith
;
Chen, Xing
;
Long, Sihui
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/04
*Staphylococcus aureus
*combinatorial chemistry
*pathogen defense
*precision antimicrobial therapeutics
*virulence factors
Modulation of Carbon Nanotubes' Perturbation to the Metabolic Activity of CYP3A4 in the Liver
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2016, 卷号: 26, 期号: 6, 页码: 841-850
作者:
Wang, Wenyi
;
Zhu, Hao
;
Yan, Bing
;
Zhang, Yi
;
Wang, Yabin
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/06/20
Combinatorial Chemistry
Cyp450
Functionalized Mwcnts
Human Liver Microsome
Pharmacophores
Modulation of Carbon Nanotubes' Perturbation to the Metabolic Activity of CYP3A4 in the Liver
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2016, 卷号: 26, 期号: 6, 页码: 841-850
作者:
Zhang, Yi
;
Wang, Yabin
;
Liu, Aijuan
;
Xu, Sherry Li
;
Zhao, Bin
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2017/03/27
combinatorial chemistry
CYP450
functionalized MWCNTs
human liver microsome
pharmacophores
Counting on natural products for drug design
期刊论文
NATURE CHEMISTRY, 2016, 卷号: 8, 期号: 6, 页码: 531-541
Rodrigues, T
;
Reker, D
;
Schneider, P
;
Schneider, G
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  |  
浏览/下载:26/0
  |  
提交时间:2017/01/12
CATALYTIC ENANTIOSELECTIVE SYNTHESIS
INSPIRED COMPOUND COLLECTION
DIVERSITY-ORIENTED SYNTHESIS
RELEVANT CHEMICAL SPACE
TARGET PREDICTION
MACROMOLECULAR TARGETS
COMBINATORIAL LIBRARY
NETWORK PHARMACOLOGY
MEDICINAL CHEMISTRY
LIGAND DISCOVERY
Modulation of Carbon Nanotubes' Perturbation to the Metabolic Activity of CYP3A4 in the Liver
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2016, 卷号: 26, 期号: 6, 页码: 841-850
作者:
Zhang, Yi
;
Wang, Yabin
;
Liu, Aijuan
;
Xu, Sherry Li
;
Zhao, Bin
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/16
combinatorial chemistry
CYP450
functionalized MWCNTs
human liver
microsome
pharmacophores
Design, preparation, and selection of DNA-encoded dynamic libraries
期刊论文
CHEMICAL SCIENCE, 2015
Li, Gang
;
Zheng, Wenlu
;
Chen, Zitian
;
Zhou, Yu
;
Liu, Yu
;
Yang, Junrui
;
Huang, Yanyi
;
Li, Xiaoyu
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2017/12/03
SMALL-MOLECULE LIBRARIES
TEMPLATE-DIRECTED SYNTHESIS
PROTEIN-BINDING AGENTS
LIGAND-TARGET PAIRS
PHOTO-CROSS-LINKING
IN-VITRO SELECTION
COMBINATORIAL CHEMISTRY
CHEMICAL LIBRARIES
ADAPTIVE CHEMISTRY
COVALENT CHEMISTRY
Two novel ferrocenyl dipeptide-like compounds generated via the Ugi four-component reaction
期刊论文
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, 2015, 卷号: 71, 页码: 667-+
作者:
Shao, Guang-Kui
;
Zhao, Mei
;
Wei, Zheng
;
Ma, Jian-Ping
;
Guo, Dian-Shun
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/17
ferrocenyl dipeptide
Ugi four-component reaction
ferrocenecarboxylic
acid
crystal structure
combinatorial chemistry
hydrogen bonding
supramolecular structure
Condition-Determined Multicomponent Reactions of 1,3-Dicarbonyl Compounds and Formaldehyde
期刊论文
ACS Combinatorial Science, 2014, 卷号: 16, 期号: 11, 页码: 652-660
作者:
Liu, Changhui
;
Shen, Meng
;
Lai, Bingbing
;
Taheri, Amir
;
Gu YL(顾彦龙)
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2015/11/27
multicomponent reactions
diversity-oriented synthesis
condition-determined MCR
combinatorial chemistry
Selection of DNA-Encoded Small Molecule Libraries Against Unmodified and Non-Immobilized Protein Targets
期刊论文
angewandte chemie international edition, 2014
Zhao, Peng
;
Chen, Zitian
;
Li, Yizhou
;
Sun, Dawei
;
Gao, Yuan
;
Huang, Yanyi
;
Li, Xiaoyu
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/11/10
DNA
DNA-encoded library
DNA-templated chemistry
drug discovery
selection
IN-VITRO SELECTION
CHEMICAL LIBRARIES
LINKED DNA
TERMINAL PROTECTION
PEPTIDE LIBRARY
COMBINATORIAL CHEMISTRY
BINDING PROTEINS
MICROARRAYS
DISCOVERY
ASSAY
A DNA-templated synthesis of encoded small molecules by DNA self-assembly
期刊论文
chemical communications, 2014
Cao, Cheng
;
Zhao, Peng
;
Li, Ze
;
Chen, Zitian
;
Huang, Yanyi
;
Bai, Yu
;
Li, Xiaoyu
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/10
IN-VITRO SELECTION
CHEMICAL LIBRARIES
COMBINATORIAL CHEMISTRY
ORGANIC-SYNTHESIS
INHIBITORS
DISCOVERY
MACROCYCLES
TRANSLATION
INFLUENZA
DESIGN
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