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CORC

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Structure-Based Survey of the Binding Modes of BACE1 Inhibitors 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 2, 页码: 880-889
作者:  Hu, Hangchen;  Chen, Zhaoqiang;  Xu, Xiang;  Xuo, Yechun
收藏  |  浏览/下载：37/0  |  提交时间：2020/07/01
Inhibition of sphingomyelin synthase 1 ameliorates alzheimer-like pathology in APP/PS1 transgenic mice through promoting lysosomal degradation of BACE1 期刊论文
EXPERIMENTAL NEUROLOGY, 2019, 卷号: 311
作者:  Lu, Mei-Hong;  Ji, Wen-Li;  Xu, De-En;  Yao, Pei-Pei;  Zhao, Xiu-Yun
收藏  |  浏览/下载：22/0  |  提交时间：2019/12/04
The correlation between accumulation of amyloid beta with enhanced neuroinflammation and cognitive impairment after intraventricular hemorrhage 期刊论文
JOURNAL OF NEUROSURGERY, 2019, 卷号: 131, 期号: 1
作者:  Jiang, Conglin;  Zou, Xiang;  Zhu, Renqing;  Shi, Yimin;  Wu, Zehan
收藏  |  浏览/下载：74/0  |  提交时间：2019/12/05
Small interfering RNA delivery to the neurons near the amyloid plaques for improved treatment of Alzheimer's disease 期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 3
作者:  Guo, Qian;  Zheng, Xiaoyao;  Yang, Peng;  Pang, Xiaoying;  Qian, Kang
收藏  |  浏览/下载：12/0  |  提交时间：2019/12/05
Chronic Sleep Restriction Induces Aβ Accumulation by Disrupting the Balance of Aβ Production and Clearance in Rats. 期刊论文
Neurochemical research, 2019, 卷号: 44, 页码: 859-873
作者:  Zhao Beiyu;  Liu Peng;  Wei Meng;  Li Yanbo;  Liu Jie
收藏  |  浏览/下载：139/0  |  提交时间：2019/11/19
Discovery of a series of selective and cell permeable beta-secretase (BACE1) inhibitors by fragment linking with the assistance of STD-NMR 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 92
作者:  Fang, Wei-Shuo;  Sun, De-yang;  Yang, Shuang;  Cheng, Chen;  Moschke, Katrin
收藏  |  浏览/下载：8/0  |  提交时间：2019/12/05
MicroRNA-200a-3p Mediates Neuroprotection in Alzheimer-Related Deficits and Attenuates Amyloid-Beta Overproduction and Tau Hyperphosphorylation via Coregulating BACE1 and PRKACB 期刊论文
2019, 卷号: 10, 页码: 806
作者:  Wang, Linlin;  Liu, Jianghong;  Wang, Qian;  Jiang, Hailun;  Zeng, Li
收藏  |  浏览/下载：13/0  |  提交时间：2020/01/03
Discovery of a series of selective and cell permeable beta-secretase (BACE1) inhibitors by fragment linking with the assistance of STD-NMR 期刊论文
2019, 卷号: 92, 页码: 103253
作者:  Fang Wei-Shuo;  Sun De-Yang;  Yang Shuang;  Cheng Chen;  Moschke Katrin
收藏  |  浏览/下载：14/0  |  提交时间：2020/01/03
Protopanaxadiol derivative DDPU improves behavior and cognitive deficit in AD mice involving regulation of both ER stress and autophagy 期刊论文
NEUROPHARMACOLOGY, 2018, 卷号: 130, 页码: 77-91
作者:  Guo, Xiaodan;  Lv, Jianlu;  Lu, Jian;  Fan, Lei;  Huang, Xi
收藏  |  浏览/下载：54/0  |  提交时间：2019/01/08
Systemic delivery of BACE1 siRNA through neuron-targeted nanocomplexes for treatment of Alzheimer's disease 期刊论文
JOURNAL OF CONTROLLED RELEASE, 2018, 卷号: 279
作者:  Wang, Pengzhen;  Zheng, Xiaoyao;  Guo, Qian;  Yang, Peng;  Pang, Xiaoying
收藏  |  浏览/下载：50/0  |  提交时间：2019/12/05

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