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Metabolic Study of Stable Isotope Labeled Indolinone Derivative in Hepatocyte Cell by UPLC/Q TOF MS
期刊论文
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2021, 卷号: 32, 期号: 6, 页码: 1538-1544
作者:
Yang, Jixia
;
Zhang, Gongzheng
;
Wang, Zhaoyang
;
Meng, Jian
;
Wen, Hongliang
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/12/16
indolinone derivatives
alpha-synuclein
[C-3(2), N-15]-isotope labeling, metabolite
UPLC/QTOF
Advances in the development of imaging probes and aggregation inhibitors for alpha-synuclein
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 4, 页码: 483-498
作者:
Xu, Ming-ming
;
Ryan, Philip
;
Rudrawar, Santosh
;
Quinn, Ronald J.
;
Zhang, Hai-yan
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  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
Parkinson's disease
alpha-synuclein
imaging probes
aggregation inhibitors
thioflavin-T
mass spectrometry
advancesinthedevelopmentofimagingprobesandaggregationinhibitorsforalphasynuclein
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 4, 页码: 483
作者:
Xu Mingming
;
Ryan Philip
;
Rudrawar Santosh
;
Quinn Ronald J
;
Zhang Haiyan
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
Parkinson’s disease
alpha-synuclein
imaging probes
aggregation inhibitors
thioflavin-T
mass spectrometry
Identification of a New alpha-Synuclein Aggregation Inhibitor via Mass Spectrometry Based Screening
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 6, 页码: 2683-2691
作者:
Xu, Mingming
;
Loa-Kum-Cheung, Wendy
;
Zhang, Haiyan
;
Quinn, Ronald J.
;
Mellick, George D.
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
Parkinson's disease
alpha-synuclein
aggregation
mass spectrometry
screening
inhibitor
Naturally occurring autoantibodies against alpha-synuclein rescues memory and motor deficits and attenuates alpha-synuclein pathology in mouse model of Parkinson's disease
期刊论文
NEUROBIOLOGY OF DISEASE, 2019, 卷号: 124, 页码: 202-217
作者:
Huang, Ya-ru
;
Xie, Xi-xiu
;
Ji, Mei
;
Yu, Xiao-lin
;
Zhu, Jie
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2019/04/03
Parkinson's disease
alpha-Synuclein
Naturally occurring autoantibodies
A53T mice
WIG
Gastrodin protects dopaminergic neurons via insulin-like pathway in a Parkinson's disease model
期刊论文
BMC NEUROSCIENCE, 2019, 卷号: 20
作者:
Yan, Jinyuan
;
Yang, Zhongshan
;
Zhao, Ninghui
;
Li, Zhiwei
;
Cao, Xia
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/04
Gastrodin
Dopamine neurons
alpha-Synuclein
DAF-2
DAF-16 pathway
Parkinson's disease
Complex of EGCG with Cu(II) Suppresses Amyloid Aggregation and Cu(II)-Induced Cytotoxicity of alpha-Synuclein
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 16
作者:
Teng, Yilong
;
Zhao, Juan
;
Ding, Lulu
;
Ding, Yu
;
Zhou, Ping
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/12/05
Parkinson's disease
alpha-synuclein
copper
EGCG
complex
Alpha-synuclein induces microglial migration via PKM2-dependent glycolysis.
期刊论文
International journal of biological macromolecules, 2019
作者:
Qiao Hongfei
;
He Xijing
;
Zhang Qiaojun
;
Yuan Haifeng
;
Wang Dong
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/11/19
PKM2
Microglial
Alpha-synuclein
Aerobic glycolysis
alpha-Synuclein: A Multifunctional Player in Exocytosis, Endocytosis, and Vesicle Recycling
期刊论文
FRONTIERS IN NEUROSCIENCE, 2019, 卷号: 13
作者:
Huang, Mingzhu
;
Wang, Bianbian
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/11/19
vesicle recycling
Parkinson's disease
exocytosis
alpha-synuclein
endocytosis
Neuroprotective effects of lithium on a chronic MPTP mouse model of Parkinson's disease via regulation of alpha-synuclein methylation
期刊论文
MOLECULAR MEDICINE REPORTS, 2019, 卷号: 19, 期号: 6
作者:
Liu, Hui
;
Cheng, Jiwei
;
Zhu, Yudan
;
Xiao, Qian
;
Bai, Yu
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/12/05
Parkinson's disease
DNA methylation
lithium
alpha-synuclein
nigral neuron
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