×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
上海药物研究所 [314]
中国农业科学院 [12]
上海中医药大学 [9]
中国医学科学院 北京... [7]
复旦大学上海医学院 [6]
广州生物医药与健康研... [4]
更多...
内容类型
期刊论文 [310]
会议论文 [55]
专著章节 [1]
发表日期
2021 [5]
2020 [5]
2019 [19]
2018 [20]
2017 [14]
2016 [16]
更多...
学科主题
Cell Biolo... [4]
植物保护 [3]
农业基础科学 [2]
微生物学 [2]
分子生物学 [1]
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共366条,第1-10条
帮助
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine
期刊论文
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:
Xue, Yaru
;
Ren, Xuelian
;
Zhu, Zhengdan
;
Lei, Peng
;
Liu, Mengling
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/01/18
3-n-butylphthalide
Hepatotoxicity
Oxidative stresses
Covalent protein modification
Drug-drug interaction
A validated HPLC-MS/MS method for determination of simmitecan and its metabolite chimmitecan in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 8
作者:
Zhou, Jun
;
Zhan, Yan
;
Zhong, Dafang
;
Chen, Xiaoyan
;
Zhang, Yifan
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2021/11/04
chimmitecan
mass spectrometry
pharmacokinetics
simmitecan
solid tumors
Liquid chromatography-mass spectrometry method for the quantification of an anti-sclerostin monoclonal antibody in cynomolgus monkey serum
期刊论文
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2021, 卷号: 11, 期号: 4, 页码: 472-479
作者:
Gao, Yuxiong
;
Chen, Zhendong
;
Yang, Changyong
;
Zhong, Dafang
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/11/04
Anti-sclerostin monoclonal antibody (SHR-1222)
LC-MS/MS
Anti-drug antibody
Toxicokinetic
New development and update on China Bioanalysis Forum
期刊论文
BIOANALYSIS, 2021, 页码: 3
作者:
Jin, Fan
;
Tang, Daniel
;
Dong, Kelly
;
Zhong, Dafang
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2021/05/24
CBF
China Bioanalysis Forum
China Bioanalytical regulation
Chinese Pharmaceutical Association
Characterization and quantitative determination of henagliflozin metabolites in humans
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 192, 页码: 8
作者:
Chen, Zhendong
;
Li, Liang
;
Zhan, Yan
;
Zhang, Yifan
;
Liu, Haiyan
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/05/24
Henagliflozin
Metabolism
LC-MS/MS
Direct quantification of anorethidrani disuccinate and determination of sterol metabolites by chemical derivatization combined with LC-MS/MS: Application to a Phase I pharmacokinetic study in humans
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2020, 卷号: 1157, 页码: 9
作者:
Jiang, Jinfang
;
Li, Liang
;
Lu, Youming
;
Chen, Yunhui
;
Chen, Xiaoyan
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/12/24
Anorethidrani disuccinate
ACP
Sterol metabolite
Glycidyl trimethyl ammonium chloride
LC-MS/MS
Characterization of covalent binding of tyrosine kinase inhibitors to plasma proteins
期刊论文
DRUG METABOLISM AND PHARMACOKINETICS, 2020, 卷号: 35, 期号: 5, 页码: 456-465
作者:
Liu, Xiaoyun
;
Feng, Dan
;
Zheng, Mingyue
;
Cui, Yongmei
;
Zhong, Dafang
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/12/21
Covalent tyrosine kinase inhibitors
Covalent binding
Human serum albumin
Molecular docking
Quantitative calculations
Linear modeling
Species difference
Safety, Clinical Activity, and Pharmacokinetics of Al flutinib (AST2818) in Patients With Advanced NSCLC With EGFR T790M Mutation
期刊论文
JOURNAL OF THORACIC ONCOLOGY, 2020, 卷号: 15, 期号: 6, 页码: 1015-1026
作者:
Shi, Yuankai
;
Zhang, Shucai
;
Hu, Xingsheng
;
Feng, Jifeng
;
Ma, Zhiyong
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/12/24
Alflutinib
NSCLC
EGFR T790M mutation
Efficacy
Safety
Technologies to improve the sensitivity of existing chromatographic methods used for bioanalytical studies
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2020, 卷号: 34, 期号: 3, 页码: 13
作者:
Chen, Zhendong
;
Gao, Yuxiong
;
Zhong, Dafang
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
chromatographic methods
clean-up efficiency
derivatization
high-resolution chromatography
recovery
sensitivity
The 7th China Bioanalysis Forum Annual Meeting
期刊论文
BIOANALYSIS, 2020, 卷号: 12, 期号: 2, 页码: 71-74
作者:
Jin, Fan
;
Tang, Daniel
;
Dong, Kelly
;
Zhong, Dafang
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
bioanalytical regulation
CBF
China Bioanalysis Forum
China regulatory reform
ICH M10
©版权所有 ©2017 CSpace - Powered by
CSpace