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Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:
Wang, Z (Wang, Zhen)[ 1 ]
;
Jiang, XR (Jiang, Xiangrui)[ 1 ]
;
Zhang, XL (Zhang, Xianglei)[ 1,2 ]
;
Tian, GH (Tian, Guanghui)[ 3 ]
;
Yang, RL (Yang, Rulei)[ 3 ]
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浏览/下载:137/0
  |  
提交时间:2019/06/28
Strain engineering for thermal conductivity of diamond nanothread forests
期刊论文
JOURNAL OF PHYSICS D-APPLIED PHYSICS, 2019, 卷号: 52
作者:
Xue, Yixuan[1]
;
Chen, Yang[2]
;
Li, Zhen[3]
;
Jiang, Jin-Wu[4]
;
Zhang, Yingyan[5]
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  |  
浏览/下载:26/0
  |  
提交时间:2019/04/22
diamond nanothread
thermal conductivity
molecular dynamics
anisotropy
Early increase of neutrophil-to-lymphocyte ratio predicts 30-day mortality in patients with spontaneous intracerebral hemorrhage
期刊论文
CNS neuroscience & therapeutics, 2019, 卷号: 25, 页码: 30-35
作者:
Wang Fei[1]
;
Xu Feng[2]
;
Quan Ye[3]
;
Wang Li[4]
;
Xia Jian-Jun[5]
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  |  
浏览/下载:61/0
  |  
提交时间:2019/04/22
inflammation
mortality
neutrophil-to-lymphocyte ratio
spontaneous intracerebral hemorrhage
ZIF-8-Derived Hollow Carbon for Efficient Adsorption of Antibiotics
期刊论文
Nanomaterials (Basel, Switzerland), 2019, 卷号: 9
作者:
Tang Hongmei[1]
;
Li Wenyao[2]
;
Jiang Haishun[3]
;
Lin Runjia[4]
;
Wang Zhe[5]
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  |  
浏览/下载:24/0
  |  
提交时间:2019/04/22
ZIF-8
adsorbent
antibiotics
hollow carbon
Fast Electromagnetic Analysis of a 3-D Magnetic Circuit in a Balanced Armature Receiver
期刊论文
IEEE TRANSACTIONS ON MAGNETICS, 2019, 卷号: 55
作者:
Xu, Dan-Ping[1]
;
Jiang, Yuan-Wu[2]
;
Zhang, Hong-li[3]
;
Hwang, Sang-Moon[4]
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  |  
浏览/下载:19/0
  |  
提交时间:2019/04/22
3-D magnetic circuit
balanced armature (BA) receiver
equivalent magnetic circuit (EMC)
nonlinear magnetic material
U-shaped armature
20(S)-protopanaxadiol induces apoptosis in human umbilical vein endothelial cells by activating the PERK-eIF2alpha-ATF4 signaling pathway
期刊论文
Journal of cellular biochemistry, 2019, 卷号: 120, 页码: 5085-5096
作者:
Wang Xue[1]
;
Xia Hua-Ying[2]
;
Qin Hong-You[3]
;
Kang Xiang-Ping[4]
;
Hu Hai-Yan[5]
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  |  
浏览/下载:43/0
  |  
提交时间:2019/04/22
ATF4
apoptosis
endoplasmic reticulum stress (ER stress)
human umbilical vein endothelial cells (HUVECs)
protein kinase R-like endoplasmic reticulum kinase (PERK)
protopanaxadiol (PPD)
small interfering RNA (siRNA)
Rheological behavior of titania ink and mechanical properties of titania ceramic structures by 3D direct ink writing using high solid loading titania ceramic ink
期刊论文
JOURNAL OF ALLOYS AND COMPOUNDS, 2019, 卷号: 783, 页码: 321-328
作者:
Chen, Tao[1]
;
Sun, Aihua[2]
;
Chu, Chengyi[3]
;
Wu, Huansheng[4]
;
Wang, Jiang[5]
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  |  
浏览/下载:32/0
  |  
提交时间:2019/04/22
Titania ceramic
High solid loading
Direct ink writing
Rheological behavior
Compressive strength
Serum iron levels are an independent predictor of in-hospital mortality of critically ill patients: a retrospective, single-institution study
期刊论文
The Journal of international medical research, 2019, 卷号: 47, 页码: 66-75
作者:
Xia Jian-Jun[1]
;
Wang Fei[2]
;
Jiang Xiao-Nan[3]
;
Jiang Ting-Ting[4]
;
Shen Li-Juan[5]
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  |  
浏览/下载:45/0
  |  
提交时间:2019/04/22
Critical illness
intensive care unit
mortality
prognosis
serum iron
survival analysis
Luteolin decreases the yield of influenza A virus in vitro by interfering with the coat protein I complex expression
期刊论文
Journal of natural medicines, 2019
作者:
Yan Haiyan[1]
;
Ma Linlin[2]
;
Wang Huiqiang[3]
;
Wu Shuo[4]
;
Huang Hua[5]
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/04/22
Antiviral activity
COPI
Influenza A virus
Luteolin
The effect of reduced graphene oxide on microstructure and thermoelectric properties of Nb-doped A-site-deficient SrTiO3 ceramics
期刊论文
JOURNAL OF ALLOYS AND COMPOUNDS, 2019, 卷号: 786, 页码: 884-893
作者:
Wu, Cao[1]
;
Li, Jia[2]
;
Fan, Yuchi[3]
;
Xing, Juanjuan[4]
;
Gu, Hui[5]
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  |  
浏览/下载:50/0
  |  
提交时间:2019/04/22
Thermoelectric properties
Composites
Perovskite
Graphene
Secondary phase
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