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HINGRL: predicting drug-disease associations with graph representation learning on heterogeneous information networks
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 卷号: 23, 期号: 1, 页码: 1-15
作者:
Zhao, BW (Zhao, Bo-Wei) [1] , [2]
;
Hu, L (Hu, Lun) [2]
;
You, ZH (You, Zhu-Hong) [3] , [4]
;
Wang, L (Wang, Lei) [5]
;
Su, XR (Su, Xiao-Rui) [1] , [2]
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/05/06
drug-disease associations
prediction
heterogeneous information network
graph representation learning
drug repositioning
MGRL: Predicting Drug-Disease Associations Based on Multi-Graph Representation Learning
期刊论文
FRONTIERS IN GENETICS, 2021, 卷号: 12, 期号: 4, 页码: 1-8
作者:
Zhao, BW (Zhao, Bo-Wei)[ 1,2,3 ]
;
You, ZH (You, Zhu-Hong)[ 1,2,3 ]
;
Wong, L (Wong, Leon)[ 1,2,3 ]
;
Zhang, P (Zhang, Ping)[ 4 ]
;
Li, HY (Li, Hao-Yuan)[ 5 ]
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/05/06
drug
disease
drug repositioning
multi-graph representation learning
graph embedding
A Novel Method to Predict Drug-Target Interactions Based on Large-Scale Graph Representation Learning
期刊论文
CANCERS, 2021, 卷号: 13, 期号: 9, 页码: 1-12
作者:
Zhao, BW (Zhao, Bo-Wei) 1 , 2 , 3
;
You, ZH (You, Zhu-Hong) 1 , 2 , 3
;
Hu, L (Hu, Lun) 1 , 2 , 3
;
Guo, ZH (Guo, Zhen-Hao) 1 , 2 , 3
;
Wang, L (Wang, Lei) 1 , 2 , 3
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  |  
浏览/下载:32/0
  |  
提交时间:2021/07/27
drug discoverydrug-target interactionslarge-scale graph representation learningcomputational method
DBMDA: A Unified Embedding for Sequence-Based miRNA Similarity Measure with Applications to Predict and Validate miRNA-Disease Associations
期刊论文
MOLECULAR THERAPY-NUCLEIC ACIDS, 2020, 卷号: 19, 期号: 3, 页码: 602-611
作者:
Zheng, K (Zheng, Kai)[ 1 ]
;
You, ZH (You, Zhu-Hong)[ 2 ]
;
Wang, L (Wang, Lei)[ 2,3 ]
;
Zhou, Y (Zhou, Yong)[ 1 ]
;
Li, LP (Li, Li-Ping)[ 2 ]
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  |  
浏览/下载:48/0
  |  
提交时间:2020/04/21
Identification of potential drug-targets by combining evolutionary information extracted from frequency profiles and molecular topological structures
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 卷号: 96, 期号: 2, 页码: 758-767
作者:
Wang, L (Wang, Lei)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 2 ]
;
Li, LP (Li, Li-Ping)[ 2 ]
;
Yan, X (Yan, Xin)[ 3 ]
;
Zhang, W (Zhang, Wei)[ 1 ]
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  |  
浏览/下载:47/0
  |  
提交时间:2020/11/04
drug-target interaction
rotation forest
two-dimensional principal component analysis
Incorporating chemical sub-structures and protein evolutionary information for inferring drug-target interactions
期刊论文
SCIENTIFIC REPORTS, 2020, 卷号: 10, 期号: 1, 页码: 1-11
作者:
Wang, L (Wang, Lei)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 2 ]
;
Li, LP (Li, Li-Ping)[ 2 ]
;
Yan, X (Yan, Xin)[ 3 ]
;
Zhang, W (Zhang, Wei)[ 1 ]
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  |  
浏览/下载:25/0
  |  
提交时间:2020/12/09
Improved Prediction of Protein-Protein Interactions Using Descriptors Derived From PSSM via Gray Level Co-Occurrence Matrix
期刊论文
IEEE ACCESS, 2019, 卷号: 7, 期号: 4, 页码: 49456-49465
作者:
Zhu, HJ (Zhu, Hui-Juan)[ 1 ]
;
You, ZH (You, Zhu-Hong)[ 2,3 ]
;
Shi, WL (Shi, Wei-Lei)[ 2 ]
;
Xu, SK (Xu, Shou-Kun)[ 4 ]
;
Jiang, TH (Jiang, Tong-Hai)[ 2,3 ]
收藏
  |  
浏览/下载:108/0
  |  
提交时间:2019/05/16
Protein-protein interactions
rotation forest
position-specific scoring matrix
gray level co-occurrence matrix
Dynamic Parameter Analysis of Spindle Bearing Using 3-Dimension Quasi-Dynamic Model
期刊论文
MATHEMATICAL PROBLEMS IN ENGINEERING, 2019
作者:
Yu, Jie[1]
;
Li, Songsheng[2]
;
Chen, Xiaoyang[3]
;
He, Lei[4]
;
Yuan, Wei[5]
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/04/22
Driving factors and predictions of CO2 emission in China's coal chemical industry
期刊论文
JOURNAL OF CLEANER PRODUCTION, 2019, 卷号: 210, 页码: 1131-1140
作者:
Zhang, Lingyun[1]
;
Shen, Qun[2]
;
Wang, Minquan[3]
;
Sun, Nannan[4]
;
Wei, Wei[5]
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/04/22
CO2 emission
Coal chemical industry
Driving factors
Scenario method
Cluster analysis of Dendrobium officinale from different populations through agronomy characterization
期刊论文
Zhongguo Zhong yao za zhi, 2019, 卷号: 44, 页码: 53-58
作者:
Yu Wen-Xia[1]
;
Dong Xiao-Man[2]
;
Lei Zhou-Xi[3]
;
Yuan Yuan[4]
;
Shun Qing-Sheng[5]
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/04/22
Dendrobium officinale
cluster analysis
genetic similarities
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