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MGRL: Predicting Drug-Disease Associations Based on Multi-Graph Representation Learning
期刊论文
FRONTIERS IN GENETICS, 2021, 卷号: 12, 期号: 4, 页码: 1-8
作者:
Zhao, BW (Zhao, Bo-Wei)[ 1,2,3 ]
;
You, ZH (You, Zhu-Hong)[ 1,2,3 ]
;
Wong, L (Wong, Leon)[ 1,2,3 ]
;
Zhang, P (Zhang, Ping)[ 4 ]
;
Li, HY (Li, Hao-Yuan)[ 5 ]
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/05/06
drug
disease
drug repositioning
multi-graph representation learning
graph embedding
GCNCDA: A new method for predicting circRNA-disease associations based on Graph Convolutional Network Algorithm
期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2020, 卷号: 16, 期号: 5, 页码: 1-19
作者:
Wang, L (Wang, Lei)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 2 ]
;
Li, YM (Li, Yang-Ming)[ 3 ]
;
Zheng, K (Zheng, Kai)[ 4 ]
;
Huang, YA (Huang, Yu-An)[ 5 ]
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/06
iCDA-CGR: Identification of circRNA-disease associations based on Chaos Game Representation
期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2020, 卷号: 16, 期号: 5, 页码: 1-22
作者:
Zheng, K (Zheng, Kai)[ 1 ]
;
You, ZH (You, Zhu-Hong)[ 2 ]
;
Li, JQ (Li, Jian-Qiang)[ 3 ]
;
Wang, L (Wang, Lei)[ 2,4 ]
;
Guo, ZH (Guo, Zhen-Hao)[ 2 ]
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/06
Learning Representations to Predict Intermolecular Interactions on Large-Scale Heterogeneous Molecular Association Network
期刊论文
ISCIENCE, 2020, 卷号: 23, 期号: 7, 页码: 1-16
作者:
Yi, HC (Yi, Hai-Cheng)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 1,2 ]
;
Huang, DS (Huang, De-Shuang)[ 3 ]
;
Guo, ZH (Guo, Zhen-Hao)[ 1 ]
;
Chan, KCC (Chan, Keith C. C.)[ 4 ]
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/09/09
NLPEI: A Novel Self-Interacting Protein Prediction Model Based on Natural Language Processing and Evolutionary Information
期刊论文
EVOLUTIONARY BIOINFORMATICS, 2020, 卷号: 16, 期号: 12, 页码: 1-12
作者:
Jia, LN (Jia, Li-Na)[ 1 ]
;
Yan, X (Yan, Xin)[ 2,3 ]
;
You, ZH (You, Zhu-Hong)[ 4 ]
;
Zhou, X (Zhou, Xi)[ 4 ]
;
Li, LP (Li, Li-Ping)[ 4 ]
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/03/19
Self-interacting protein
natural language processing
evolutionary information
stacked auto-encoder
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:
Wang, Z (Wang, Zhen)[ 1 ]
;
Jiang, XR (Jiang, Xiangrui)[ 1 ]
;
Zhang, XL (Zhang, Xianglei)[ 1,2 ]
;
Tian, GH (Tian, Guanghui)[ 3 ]
;
Yang, RL (Yang, Rulei)[ 3 ]
收藏
  |  
浏览/下载:137/0
  |  
提交时间:2019/06/28
SLFN5 suppresses cancer cell migration and invasion by inhibiting MT1-MMP expression via AKT/GSK-3β/β-catenin pathway
期刊论文
Cellular signalling, 2019, 卷号: 59, 页码: 1-12
作者:
Wan Guoqing[1]
;
Liu Yihao[2]
;
Zhu Jiang[3]
;
Guo Lijuan[4]
;
Li Chenhong[5]
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/04/22
Cancer
Invasion
Matrix metalloproteinase 14
Schlafen family member-5 (SLFN5)
β-catenin
Evolution of the microstructure and solute distribution of Sn-10wt% Bi alloys during electromagnetic field-assisted directional solidification
期刊论文
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY, 2019, 卷号: 35, 页码: 568-577
作者:
Shen, Zhe[1]
;
Peng, Minghu[2]
;
Zhu, Dongsheng[3]
;
Zheng, Tianxiang[4]
;
Zhong, Yunbo[5]
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/04/22
Directional solidification
Sn-Bi alloy
Forced flow
Solute distribution
Numerical simulation
Electromagnetic field
Pharmacological Targeting of STK19 Inhibits Oncogenic NRAS-Driven Melanomagenesis
期刊论文
Cell, 2019, 卷号: 176, 页码: 1113-1127.e16
作者:
Yin Chengqian[1]
;
Zhu Bo[2]
;
Zhang Ting[3]
;
Liu Tongzheng[4]
;
Chen Shuyang[5]
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2019/04/22
NRAS
RAS
STK19
cancer
drug screening
kinase inhibitor
melanoma
melanomagenesis
targeted cancer therapy
Functional near-infrared spectroscopy in the evaluation of urban rail transit drivers' mental workload under simulated driving conditions
期刊论文
Ergonomics, 2019, 页码: 1-14
作者:
Li Lan-Peng[1]
;
Liu Zhi-Gang[2]
;
Zhu Hai-Yan[3]
;
Zhu Lin[4]
;
Huang Yuan-Chun[5]
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/04/22
Mental workload
driving simulator
functional near-infrared spectroscopy (fNIRS)
oxy-hemoglobin (oxy-Hb)
urban rail transit driver
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