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山东大学 [36]
武汉大学 [5]
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武汉物理与数学研究所 [1]
复旦大学上海医学院 [1]
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期刊论文 [48]
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Differences in Changes in Carbon Dioxide Emissions among China’s Transportation Subsectors: A Structural Decomposition Analysis
期刊论文
Emerging Markets Finance and Trade, 2019, 卷号: Vol.55 No.6, 页码: 1294-1311
作者:
Rui Xie
;
Linyuan Huang
;
Boshi Tian
;
Jiayu Fang
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/13
carbon
emissions
structural
decomposition
analysis
transportation
industry
Exploiting the Tolerant Region I of the Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) Binding Pocket: Discovery of Potent Diarylpyrimidine-Typed HIV-1 NNRTIs against Wild-Type and E138K Mutant Virus with Significantly Improved Water Solubility and Favorable Safety Profiles
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 4, 页码: 2083-2098
作者:
Huang, Boshi
;
Chen, Wenmin
;
Zhao, Tong
;
Li, Zhenyu
;
Jiang, Xiangyi
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/11
Differences in Changes in Carbon Dioxide Emissions among China's Transportation Subsectors: A Structural Decomposition Analysis
期刊论文
Emerging Markets Finance and Trade, 2019, 卷号: Vol.55 No.6, 页码: 1294-1311
作者:
Xie, Rui
;
Huang, Linyuan
;
Tian, Boshi
;
Fang, Jiayu
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/17
Energy
Transportation
Differences in Changes in Carbon Dioxide Emissions among China's Transportation Subsectors: A Structural Decomposition Analysis
期刊论文
Emerging Markets Finance and Trade, 2019, 卷号: Vol.55 No.6, 页码: 1294-1311
作者:
Xie, Rui
;
Huang, Linyuan
;
Tian, Boshi
;
Fang, Jiayu
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/17
Energy
Transportation
Targeting the entrance channel of NNIBP: Discovery of diarylnicotinamide 1,4-disubstituted 1,2,3-triazoles as novel HIV-1 NNRTIs with high potency against wild-type and E138K mutant virus
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 151, 页码: 339-350
作者:
Tian, Ye
;
Liu, Zhaoqiang
;
Liu, Jinghan
;
Huang, Boshi
;
Kang, Dongwei
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  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
HIV-1
NNRTIs
Triazole
Diarylnicotinamide
Entrance channel
Drug
design
Design, synthesis and biological evaluation of tacrine-1,2,3-triazole derivatives as potent cholinesterase inhibitors
期刊论文
MEDCHEMCOMM, 2018, 卷号: 9, 期号: 1, 页码: 149-159
作者:
Wu, Gaochan
;
Gao, Yun
;
Kang, Dongwei
;
Huang, Boshi
;
Huo, Zhipeng
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/11
First discovery of a potential carbonate prodrug of NNRTI drug candidate RDEA427 with submicromolar inhibitory activity against HIV-1 K103N/Y181C double mutant strain
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 8, 页码: 1348-1351
作者:
Huang, Boshi
;
Liu, Xinhao
;
Tian, Ye
;
Kang, Dongwei
;
Zhou, Zhongxia
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/11
HIV-1 NNRTI
RDEA427
Carbonate prodrug
Anti-HIV activity
Metabolic
stability
Further Exploring Solvent-Exposed Tolerant Regions of Allosteric Binding Pocket for Novel HIV-1 NNRTIs Discovery
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 4, 页码: 370-375
作者:
Kang, Dongwei
;
Wang, Zhao
;
Zhang, Heng
;
Wu, Gaochan
;
Zhao, Tong
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/11
HIV-1
NNRTIs
DAPY
tolerant regions
drug design
Novel diaryltriazines with a picolinonitrile moiety as potent HIV-1 RT inhibitors: a patent evaluation of WO2016059647(A2)
期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2017, 卷号: 27, 期号: 1, 页码: 9-15
作者:
Huang, Boshi
;
Zhou, Zhongxia
;
Kang, Dongwei
;
Li, Wanzhuo
;
Chen, Zihui
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/16
Diaryltriazine
HIV-1 RT inhibitors
picolinonitrile
modeling
simulation
highly conserved residues
Discovery of novel piperidine-substituted indolylarylsulfones as potent HIV NNRTIs via structure-guided scaffold morphing and fragment rearrangement
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 126, 页码: 190-201
作者:
Li, Xiao
;
Gao, Ping
;
Huang, Boshi
;
Zhou, Zhongxia
;
Yu, Zhao
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
HIV
NNRTIs
Indolylarylsulfones
Antiviral activity
SAR
Molecular
modeling
Chemical space
Drug design
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