CORC

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CORC

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Kinetics-Driven Drug Design Strategy for Next-Generation Acetylcholinesterase Inhibitors to Clinical Candidate 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 4, 页码: 1844-1855
作者:  Zhou, Yu;  Fu, Yan;  Yin, Wanchao;  Li, Jian;  Wang, Wei
收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24
Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 20
作者:  Zhang, Rui;  Li, Heng;  Zhang, Xianglei;  Li, Jian;  Su, Haixia
收藏  |  浏览/下载：23/0  |  提交时间：2021/05/24
DC591017, a phosphodiesterase-4 (PDE4) inhibitor with robust anti-inflammation through regulating PKA-CREB signaling 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 15
作者:  Li, Heng;  Li, Jian;  Zhang, Xianglei;  Feng, Chunlan;  Fan, Chen
收藏  |  浏览/下载：28/0  |  提交时间：2020/12/24
DC591017, a phosphodiesterase-4 (PDE4) inhibitor with robust anti-inflammation through regulating PKA-CREB signaling 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 15
作者:  Li, Heng;  Li, Jian;  Zhang, Xianglei;  Feng, Chunlan;  Fan, Chen
收藏  |  浏览/下载：40/0  |  提交时间：2020/12/24
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease 期刊论文
SCIENCE, 2020, 卷号: 368, 期号: 6497, 页码: 1331-+
作者:  Dai, Wenhao;  Zhang, Bing;  Jiang, Xia-Ming;  Su, Haixia;  Li, Jian
收藏  |  浏览/下载：30/0  |  提交时间：2020/12/24
Structure of M-pro from SARS-CoV-2 and discovery of its inhibitors 期刊论文
NATURE, 2020, 页码: 24
作者:  Jin, Zhenming;  Du, Xiaoyu;  Xu, Yechun;  Deng, Yongqiang;  Liu, Meiqin
收藏  |  浏览/下载：41/0  |  提交时间：2020/07/01
Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 16, 页码: 7473-7488
作者:  Wang, Yulan;  Dai, Yang;  Wu, Xiaowei;  Li, Fei;  Liu, Bo
收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01
Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5579-5593
作者:  Zhang, Xianglei;  Dong, Guangyu;  Li, Heng;  Chen, Wuyan;  Li, Jian
收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01
Crystal structure of the human 5-HT1B serotonin receptor bound to an inverse agonist 期刊论文
CELL DISCOVERY, 2018, 卷号: 4
作者:  Yin, Wanchao;  Zhou, X. Edward;  Yang, Dehua;  de Waal, Parker W.;  Wang, Meitian
收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08
Crystal structure of the human 5-HT1B serotonin receptor bound to an inverse agonist 期刊论文
CELL DISCOVERY, 2018, 卷号: 4
作者:  Yin, Wanchao;  Zhou, X. Edward;  Yang, Dehua;  de Waal, Parker W.;  Wang, Meitian
收藏  |  浏览/下载：18/0  |  提交时间：2019/12/05

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