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CORC

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Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 20
作者:  Zhang, Rui;  Li, Heng;  Zhang, Xianglei;  Li, Jian;  Su, Haixia
收藏  |  浏览/下载：23/0  |  提交时间：2021/05/24
Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5579-5593
作者:  Zhang, Xianglei;  Dong, Guangyu;  Li, Heng;  Chen, Wuyan;  Li, Jian
收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01
Self-assembly of Fluorescent Dehydroberberine Enhances Mitochondria-Dependent Antitumor Efficacy 期刊论文
CHEMISTRY-A EUROPEAN JOURNAL, 2018, 卷号: 24, 期号: 39, 页码: 9812-9819
作者:  An, Ruibing;  Gu, Zhanni;  Sun, Haifeng;  Hu, Yuxuan;  Yan, Runqi
收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08
Design, synthesis, and structure-activity relationships of novel 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinoline and 5,8,12,12a-tetrahydro-6H-thieno[2 ',3 ': 4,5]pyrido[2,1-a]isoquinoline derivatives as cellular activators of adenosine 5 '-monophosphate-activated protein kinase (AMPK) 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 2017-2027
作者:  Gu, Zhanni;  Wu, Lingyan;  Duan, Yanan;  Wang, Jiang;  Zhou, Shengbin
收藏  |  浏览/下载：39/0  |  提交时间：2019/01/08
Design, synthesis and. biological evaluation of 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinolines as novel adenosine 5 '-monophosphate-activated protein kinase (AMPK) indirect activators for the treatment of type 2 diabetes 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 448-464
作者:  Zhou, Shengbin;  Duan, Yanan;  Wang, Jiang;  Zhang, Jin;  Sun, Haifeng
收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II-III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas 期刊论文
CHEMICAL REVIEWS, 2016, 卷号: 116, 期号: 2, 页码: 422-518
作者:  Zhou, Yu;  Wang, Jiang;  Gu, Zhanni;  Wang, Shuni;  Zhu, Wei
收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08
Fluorescent Coumarin-Artemisinin Conjugates as Mitochondria-Targeting Theranostic Probes for Enhanced Anticancer Activities 期刊论文
CHEMISTRY-A EUROPEAN JOURNAL, 2015, 卷号: 21, 期号: 48, 页码: 17415-17421
作者:  Zhang, Xu;  Ba, Qian;  Gu, Zhanni;  Guo, Diliang;  Zhou, Yu
收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08
Recent advances in the trifluoromethylation methodology and new CF3-containing drugs 期刊论文
JOURNAL OF FLUORINE CHEMISTRY, 2014, 卷号: 167, 页码: 37-54
作者:  Zhu, Wei;  Wang, Jiang;  Wang, Shuni;  Gu, Zhanni;  Luis Acena, Jose
收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08

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