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上海药物研究所 [11]
山东大学 [6]
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中国医学科学院 北京... [4]
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期刊论文 [41]
会议论文 [2]
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浏览/检索结果:
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Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7
作者:
Bi, Xiaoyang
;
Chen, Yu
;
Sun, Zhongya
;
Lu, Wenchao
;
Xu, Pan
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/05/24
Drug design
CBP
Bromodomain
Inhibitor
Acute myeloid leukemia
Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11
作者:
Chen, Yu
;
Bi, Xiaoyang
;
Zhang, Fengcai
;
Sun, Zhongya
;
Xu, Pan
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/12/24
In silico screening
Drug design
CBP
Bromodomain
Inhibitor
Acute Myeloblastic Leukemia
Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion
期刊论文
ADVANCED SCIENCE, 2020, 页码: 13
作者:
Sun, Zhongya
;
Zhang, Hao
;
Zhang, Yuanyuan
;
Liao, Liping
;
Zhou, Wen
收藏
  |  
浏览/下载:107/0
  |  
提交时间:2020/07/01
anti-metastasis activities
crystal structures
inhibitors
novel pockets
rho family proteins
Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 15
作者:
Lu, Wenchao
;
Wang, Jun
;
Li, Yong
;
Tao, Hongru
;
Xiong, Huan
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2020/07/01
Hippo pathway
TEAD transcription factor
Covalent inhibitor
Palmitoylation inhibitor
Measurement and Analysis of Radiation Calibration Uncertainty of Multi-Band Polarization Imager
会议论文
2019-8
作者:
Quan Zhang
;
Xin Li
;
Wenchao Zhai
;
Manchao Ding
;
Xiaobing Zheng
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2021/12/24
Metabolic regulation of gene expression by histone lactylation
期刊论文
NATURE, 2019, 卷号: 574, 期号: 7779, 页码: 575-+
作者:
Zhang, Di
;
Tang, Zhanyun
;
Huang, He
;
Zhou, Guolin
;
Cui, Chang
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/07/01
The identification of novel small-molecule inhibitors targeting WDR5-MLL1 interaction through fluorescence polarization based high-throughput screening
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 4, 页码: 638-645
作者:
Ye, Xiaoqing
;
Zhang, Rukang
;
Lian, Fulin
;
Zhang, Weiyao
;
Lu, Wenchao
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/07/01
WDR5-MLL1 interaction
Leukemia
Small-molecule
High-throughput screening
Fluorescence polarization (FP)
Continuous positive airway pressure (CPAP) vs noninvasive positive pressure ventilation (NIPPV) vs noninvasive high frequency oscillation ventilation (NHFOV) as post-extubation support in preterm neonates: protocol for an assessor-blinded, multicenter, randomized controlled trial
期刊论文
BMC PEDIATRICS, 2019, 卷号: 19
作者:
Shi, Yuan
;
De Luca, Daniele
;
Yuan, Shi
;
Wang, Jianhui
;
Long, Chen
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2019/12/04
Neonate
Noninvasive respiratory ventilation
Non invasive high frequency oscillatory ventilation
Continuous positive airway pressure (CPAP) vs noninvasive positive pressure ventilation (NIPPV) vs noninvasive high frequency oscillation ventilation (NHFOV) as post-extubation support in preterm neonates: protocol for an assessor-blinded, multicenter, randomized controlled trial
期刊论文
BMC PEDIATRICS, 2019, 卷号: 19
作者:
Shi, Yuan
;
De Luca, Daniele
;
Yuan, Shi
;
Wang, Jianhui
;
Long, Chen
收藏
  |  
浏览/下载:118/0
  |  
提交时间:2019/12/05
Neonate
Noninvasive respiratory ventilation
Non invasive high frequency oscillatory ventilation
Spread through air spaces predicts a worse survival in patients with stage I adenocarcinomas 2 cm after radical lobectomy (vol 10, pg 5308, 2018)
期刊论文
2019, 卷号: 11, 期号: 5
作者:
Yang, Lin
;
Yang, Yikun
;
Ma, Peiqing
;
Zheng, Bo
;
Liu, Wenchao
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/01/03
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