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科研机构
上海药物研究所 [9]
北京航空航天大学 [1]
中国科学院大学 [1]
云南天文台 [1]
合肥物质科学研究院 [1]
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期刊论文 [12]
会议论文 [1]
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2022 [1]
2021 [2]
2019 [1]
2018 [3]
2017 [1]
2016 [4]
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天文学 [1]
天文学:: 天体力学 [1]
天文学::天体测量学 [1]
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The facilities and performance of TianQin laser ranging station
期刊论文
CLASSICAL AND QUANTUM GRAVITY, 2022, 卷号: 39, 期号: 12
作者:
Zhang, Caishi
;
Gao, Tianquan
;
Cao, Yuyan
;
Fan, Zhongwei
;
Fu HL(伏红林)
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2022/06/13
lunar laser ranging
satellite laser ranging
precision satellite orbit determination
gravitational waves detection
Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 11
作者:
Fan, Shijie
;
Yue, Liyan
;
Wan, Wei
;
Zhang, Yuanyuan
;
Zhang, Bidong
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2021/12/16
covalent modification
probes
proteome
LC3
post-translational modification
Prolonged overall survival observed in patients with locally advanced gastric cancer receiving prophylactic simplified heated intraperitoneal chemotherapy after D2 surgery.
期刊论文
JOURNAL OF CLINICAL ONCOLOGY, 2021, 卷号: 39
作者:
Cheng, Junchi
;
Yang, Yunshan
;
Zhong, Haijun
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  |  
浏览/下载:5/0
  |  
提交时间:2022/01/10
Graph convolutional network hashing for cross-modal retrieval
会议论文
28th International Joint Conference on Artificial Intelligence, IJCAI 2019, Macao, China, 2019-08-10
作者:
Xu, Ruiqing
;
Li, Chao
;
Yan, Junchi
;
Deng, Cheng
;
Liu, Xianglong
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  |  
浏览/下载:4/0
  |  
提交时间:2019/12/30
Deciphering the role of dimer interface in intrinsic dynamics and allosteric pathways underlying the functional transformation of DNMT3A
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2018, 卷号: 1862, 期号: 7, 页码: 1667-1679
作者:
Liang, Zhongjie
;
Hu, Junchi
;
Yan, Wenying
;
Jiang, Hualiang
;
Hu, Guang
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  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
Conformational dynamics
Allosteric communication
Elastic network models, network theory, coevolution analysis
Interaction assessments of the first S-adenosylmethionine competitive inhibitor and the essential interacting partner methylosome protein 50 with protein arginine methyltransferase 5 by combined computational methods
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 495, 期号: 1, 页码: 721-727
作者:
Zhu, Kongkai
;
Jiang, Cheng-Shi
;
Hu, Junchi
;
Liu, Xigong
;
Yan, Xue
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  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
PRMT5 SAM competitive inhibitor
Molecular docking
Molecular dynamics simulation
Molecular mechanics/Poisson-Boltzmann surface area
PRMT5:MEP50 interaction
developmentofahighthroughputfluorescencepolarizationassayforthediscoveryofezh2eedinteractioninhibitors
期刊论文
actapharmacologicasinica, 2018, 卷号: 39, 期号: 2, 页码: 302
作者:
Zhu Maorong
;
Du Daohai
;
Hu Junchi
;
Li Lianchun
;
Liu Jingqiu
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2020/07/01
PRC2
EZH2
EED
protein-protein interaction
fluorescence polarization
high-throughput screening
apomorphine hydrochloride
oxyphenbutazone
nifedipine
ergonovine maleate
The Human Knockout Gene CLYBL Connects Itaconate to Vitamin B-12
期刊论文
CELL, 2017, 卷号: 171, 期号: 4, 页码: 771-+
作者:
Shen, Hongying
;
Campanello, Gregory C.
;
Flicker, Daniel
;
Grabarek, Zenon
;
Hu, Junchi
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  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
Identification of novel ezh2 inhibitors through pharmacophore-based virtual screening and biological assays
期刊论文
Bioorganic & medicinal chemistry letters, 2016, 卷号: 26, 期号: 15, 页码: 3813-3817
作者:
Wu, Yunlong
;
Hu, Junchi
;
Ding, Hong
;
Chen, Limin
;
Zhang, Yuanyuan
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/05/09
Ezh2
Epigenetics
Prc2
Computational drug design
Pharmacophore-based virtual screening
Identification of novel EZH2 inhibitors through pharmacophore-based virtual screening and biological assays
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 15, 页码: 3813-3817
作者:
Wu, Yunlong
;
Hu, Junchi
;
Ding, Hong
;
Chen, Limin
;
Zhang, Yuanyuan
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
EZH2
Epigenetics
PRC2
Computational drug design
Pharmacophore-based virtual screening
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