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科研机构
武汉理工大学 [16]
内容类型
期刊论文 [16]
发表日期
2018 [3]
2017 [6]
2016 [5]
2015 [1]
2014 [1]
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Recent Developments on Phenstatins as Potent Antimitotic Agents.
期刊论文
Current medicinal chemistry, 2018, 卷号: 25, 期号: 20, 页码: 2329-2352
作者:
Chen, Xing
;
Wang, Shi-Meng
;
Kumar, Gajjela Bharath
;
Bare, Grant A. L.
;
Leng, Jing
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/04
Antimitotic activity
Colchicine binding site
Cytotoxic activity
Structure-activity relationship
Tubulin polymerization inhibition
phenstatins.
Synthesis and biological evaluation of new tetramethylpyrazine-based chalcone derivatives as potential anti-Alzheimer agents
期刊论文
Chemical Biology & Drug Design, 2018, 卷号: 92, 期号: 5, 页码: 1859-1866
作者:
Wang, Meng
;
Qin, Hua-Li*
;
Leng, Jing
;
Ameeduzzafar
;
Amjad, Muhammad Wahab
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/04
acetylcholinesterase
amyloid β
chalcone
ligustrazine
monoamine oxidases
Rhodium(III)-catalyzed Oxidative Coupling of N-Methoxybenzamides and Ethenesulfonyl fluoride: a C-H Bond Activation Strategy for the Preparation of 2-Aryl ethenesulfonyl fluorides and Sulfonyl fluoride Substituted gamma-Lactams
期刊论文
Organic Chemistry Frontiers, 2018, 卷号: 5, 期号: 9, 页码: 1411-1415
作者:
Wang, Shi-Meng
;
Li, Chen
;
Leng, Jing
;
Bukhari, Syed Nasir Abbas
;
Qin, Hua-Li*
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  |  
浏览/下载:8/0
  |  
提交时间:2019/12/04
Synthesis of new arylisoxazole–oxindole conjugates as potent antiproliferative agents
期刊论文
Chemical Biology & Drug Design, 2017, 卷号: 89, 期号: 4, 页码: 634-638
作者:
Kumar, Gajjela Bharath
;
Bukhari, Syed Nasir Abbas*
;
Qin, Hua-Li*
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/04
antiproliferative activity
arylisoxazole–oxindole
cancer
drug discovery
nocodazole
Emerging Trends in Therapeutic Algorithm of Chronic Wound Healers: Recent Advances in Drug Delivery Systems, Concepts-to-Clinical Application and Future Prospects
期刊论文
Critical Reviews™ in Therapeutic Drug Carrier Systems, 2017, 卷号: 34, 期号: 5, 页码: 387-452
作者:
Shao, Mei
;
Hussain, Zahid*
;
Thu, Hnin Ei
;
Khan, Shahzeb
;
de Matas, Marcel
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  |  
浏览/下载:4/0
  |  
提交时间:2019/12/04
chronic wounds
nonlinear healing
conventional dressing
advanced therapies
natural and synthetic polymers
efficacy upgradation
Coumarins scaffolds as COX inhibitors
期刊论文
Bioorganic Chemistry, 2017, 卷号: 71, 页码: 146-159
作者:
Revankar, Hrishikesh Mohan
;
Bukhari, Syed Nasir Abbas*
;
Kumar, Gajjela Bharath
;
Qin, Hua-Li*
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/04
Coumarins
COX-1 enzymes
COX-2 enzymes
NSAID
Anti-inflammatory
Synthesis and mechanistic studies of curcumin analog‐based oximes as potential anticancer agents
期刊论文
Chemical Biology & Drug Design, 2017, 卷号: 90, 期号: 3, 页码: 443-449
作者:
Qin, Hua-Li*
;
Leng, Jing
;
Youssif, Bahaa G. M.
;
Amjad, Muhammad Wahab
;
Raja, Maria Abdul Ghafoor
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/04
Natural compounds
α, β‐unsaturated carbonyl
tubulin polymerization
epidermal growth factor receptor (EGFR)
multidrug resistance (MDR)
Discovery of potential anticancer multi-targeted ligustrazine based cyclohexanone and oxime analogs overcoming the cancer multidrug resistance
期刊论文
European Journal of Medicinal Chemistry, 2017, 卷号: 135, 页码: 34-48
作者:
Zha, Gao-Feng
;
Qin, Hua-Li*
;
Youssif, Bahaa G. M.
;
Amjad, Muhammad Wahab
;
Raja, Maria Abdul Ghafoor
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/04
Epidermal growth factor receptor (EGFR)
BRAF
Focal adhesion kinase (FAK)
Tubulin polymerization
Cancer cell lines
MDR
multidrug resistance
EGFR
epidermal growth factor receptor
EMEA
European Medicines Evaluation Agency
FDA
US Food and Drug Administration
NSCLC
non-small cell lung
FAK
focal adhesion kinase
RTK
receptor tyrosine kinases
MAPK
mitogen-activated protein kinase
ABC
ATP-binding cassette
NF-kB
NF-kappaB
FERM
Four-point-one, ezrin, radixin, moesin
TMP
Ligustrazine or tetramethylpyrazine
Adr
Adriamycin
DRS
death receptors
TFN
tumor necrosis factor
PI
propidium iodide
TKIs
tyrosine kinase inhibitors
FAR
fluorescence activity ratio
HRMS
high resolution mass spectra
TLC
thin layer chromatography
UV
ultraviolet
DMEM
Dulbecco's modified Eagle's medium
DMSO
dimethyl sulfoxide
IBX
2-iodoxybenzoic acid
Development of combretastatins as potent tubulin polymerization inhibitors
期刊论文
Bioorganic Chemistry, 2017, 卷号: 72, 页码: 130-147
作者:
Bukhari, Syed Nasir Abbas*
;
Kumar, Gajjela Bharath
;
Revankar, Hrishikesh Mohan
;
Qin, Hua-Li*
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/04
Combretastatin A-4
Anticancer
Antiproliferative
Isolation
Natural products
Synthesis of α,β-Unsaturated Carbonyl-Based Compounds, Oxime and Oxime Ether Analogs as Potential Anticancer Agents for Overcoming Cancer Multidrug Resistance by Modulation of Efflux Pumps in Tumor Cells
期刊论文
Journal of Medicinal Chemistry, 2016, 卷号: 59, 期号: 7, 页码: 3549-3561
作者:
Qin, Hua-Li*
;
Leng, Jing
;
Zhang, Cheng-Pan
;
Jantan, Ibrahim
;
Amjad, Muhammad Wahab
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/04
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