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科研机构
上海药物研究所 [9]
湖南大学 [2]
西北高原生物研究所 [1]
昆明植物研究所 [1]
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期刊论文 [13]
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2021 [1]
2018 [2]
2014 [3]
2012 [1]
2008 [1]
2007 [3]
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浏览/检索结果:
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Design, synthesis and bioactivity study of evodiamine derivatives as multifunctional agents for the treatment of hepatocellular carcinoma
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 114
作者:
Fan, Xiaohong
;
Deng, Jiedan
;
Shi, Tao
;
Wen, Huaixiu
;
Li, Junfang
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/11/18
Hepatocellular carcinoma
Topo I
Evodiamine
Cancer-associated fibroblasts (CAFs)
Topoisomerase I inhibitory and photocleavage activity of non-dppz DNA "light switches\' based on ruthenium complexes containing nitro group
期刊论文
APPLIED ORGANOMETALLIC CHEMISTRY, 2018, 卷号: Vol.32 No.8
作者:
Liu, XueWen
;
Huang, Jie
;
Tang, YuXuan
;
Shen, YouMing
;
Lu, JiLin
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/26
DNA "light switch\'
nitro group
non-dppz
ruthenium complex
topo I inhibition
New designed DNA light switch Ruthenium complexes as DNA photocleavers and Topoisomerase I inhibitors
期刊论文
Applied Organometallic Chemistry, 2018, 卷号: Vol.32 No.4
作者:
Liu, Xue-Wen
;
Xiao, Yang
;
Peng, Wei-Gen
;
Zhao, Li-Jin
;
Shen, You-Ming
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/26
light switch
phenazine
photocleavage
Ruthenium complex
topo I inhibition
G226, a new epipolythiodioxopiperazine derivative, triggers DNA damage and apoptosis in human cancer cells in vitro via ROS generation
期刊论文
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 12, 页码: 1546-1555
作者:
He, Peng-xing
;
Zhang, Jie
;
Che, Yong-sheng
;
He, Qiao-jun
;
Chen, Yi
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
G226
epipolythiodioxopiperazine
11 '-deoxyverticillin A
anti-cancer agent
Topo II
DNA damage
apoptosis
ROS
antioxidant
Suzuki coupling based synthesis and in vitro cytotoxic evaluation of 7-heteroaryl-substituted camptothecin analogs
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 6, 页码: 1597-1599
作者:
Wang, Lei
;
Huang, Ying
;
Zhang, Jie
;
Tong, Linjiang
;
Chen, Yi
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
Camptothecin
C-7-heteroaryl-substituted camptothecin
Suzuki coupling
Antitumor
Synthesis of 7-Triazole-substituted Camptothecin via Click Chemistry and Evaluation of in vitro Antitumor Activity
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2014, 卷号: 32, 期号: 2, 页码: 157-162
作者:
Wang, Lei
;
Yuan, Wei
;
Zhang, Jie
;
Tong, Linjiang
;
Luo, Yu
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/01/08
camptothecin
7-triazole-substituted camptothecin
click chemistry
antitumor
Synthesis and biological evaluation of new homocamptothecin analogs
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 54, 页码: 281-286
作者:
Luo, Yu
;
Yu, Shanbao
;
Tong, Linjiang
;
Huang, Qingqing
;
Lu, Wei
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
Electron-withdrawing group
Homocamptothecin
Camptothecin
Anticancer drugs
Salvicine triggers DNA double-strand breaks and apoptosis by GSH-depletion-driven H2O2 generation and topoisomerase II inhibition
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2008, 卷号: 45, 期号: 5, 页码: 627-635
作者:
Cai, Yu-Jun
;
Lu, Jin-Jian
;
Zhu, Hong
;
Xie, Hua
;
Huang, Min
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
salvicine
glutathione
H2O2
topoisomerase II
DNA double-strand breaks
free radicals
MFTZ-1, an actinomycetes subspecies-derived antitumor macrolide, functions as a novel topoisomerase II poison
期刊论文
MOLECULAR CANCER THERAPEUTICS, 2007, 卷号: 6, 期号: 11, 页码: 3059-3070
作者:
Xie, Cheng-Ying
;
Zhu, Hong
;
Lin, Li-Fling
;
Miao, Ze-Hong
;
Geng, Mei-Yu
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2015/08/17
MFTZ-1, an actinomycetes subspecies-derived antitumor macrolide, functions as a novel topoisomerase II poison
期刊论文
MOLECULAR CANCER THERAPEUTICS, 2007, 卷号: 6, 期号: 11, 页码: 3059-3070
作者:
Xie, Cheng-Ying
;
Zhu, Hong
;
Lin, Li-Fling
;
Miao, Ze-Hong
;
Geng, Mei-Yu
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
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