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浏览/检索结果: 共5条，第1-5条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 16, 页码: 7473-7488 作者:  Wang, Yulan;  Dai, Yang;  Wu, Xiaowei;  Li, Fei;  Liu, Bo 收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01 Improving the Virtual Screening Ability of Target-Specific Scoring Functions Using Deep Learning Methods 期刊论文 FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 11 作者:  Wang, Dingyan;  Cui, Chen;  Ding, Xiaoyu;  Xiong, Zhaoping;  Zheng, Mingyue 收藏  |  浏览/下载：55/0  |  提交时间：2020/07/01 virtual screening  target-specific scoring function  deep learning  drug discovery  DUD-E   Discovery of Novel Disruptor of Silencing Telomeric 1-Like (DOTI L) Inhibitors using a Target-Specific Scoring Function for the (S)-Adenosyl-L-methionine (SAM)-Dependent Methyltransferase Family 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 5, 页码: 2026-2036 作者:  Wang, Yulan;  Li, Linjuan;  Zhang, Bidong;  Xing, Jing;  Chen, Shijie 收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 Discovery of binding proteins for a protein target using protein-protein docking-based virtual screening 期刊论文 proteins structure function and bioinformatics, 2014 Zhang, Changsheng; Tang, Bo; Wang, Qian; Lai, Luhua 收藏  |  浏览/下载：2/0  |  提交时间：2015/11/13 protein-protein docking  virtual screening  protein design  protein-protein interaction prediction  binding energy landscape  TNF alpha  COMPUTATIONAL DESIGN  CRYSTAL-STRUCTURE  DRUG DESIGN  TNF-ALPHA  THERAPEUTICS  PERSPECTIVE  PREDICTION  SCAFFOLDS  EVOLUTION  BIOLOGY   Knowledge-Based Scoring Functions in Drug Design. 1. Developing a Target-Specific Method for Kinase-Ligand Interactions 期刊论文 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2010, 卷号: 50, 期号: 8, 页码: 1378-1386 作者:  Xue, Mengzhu;  Zheng, Mingyue;  Xiong, Bing;  Li, Yanlian;  Jiang, Hualiang 收藏  |  浏览/下载：6/0  |  提交时间：2019/01/08