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科研机构
北京大学 [6]
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复旦大学上海医学院 [3]
上海生物化学与细胞生... [3]
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期刊论文 [29]
学位论文 [1]
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NGPF2 triggers synaptic scaling up through ALK-LIMK-cofilin-mediated mechanisms
期刊论文
CELL REPORTS, 2021, 卷号: 36, 期号: 7, 页码: 20
作者:
Zhou, Zikai
;
He, Guiqin
;
Zhang, Xiaoyun
;
Lv, Xin
;
Zhang, Xiaolin
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2021/11/04
Design, Synthesis, and Biological Evaluation of Orally Available First-Generation Dual-Target Selective Inhibitors of Acetylcholinesterase (AChE) and Phosphodiesterase 5 (PDE5) for the Treatment of Alzheimer's Disease
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2018, 卷号: 9, 期号: 2, 页码: 328-345
作者:
Mao, Fei
;
Wang, Huan
;
Ni, Wei
;
Zheng, Xinyu
;
Wang, Manjiong
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2019/01/08
Alzheimer's disease
drug repositioning
dual-target inhibitor
AChE inhibition
PDE5 inhibition
Recording Synaptic Plasticity in Acute Hippocampal Slices Maintained in a Small-volume Recycling-, Perfusion-, and Submersion-type Chamber System
期刊论文
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2018, 期号: 131
作者:
Weng, Weiguang
;
Li, Dongxue
;
Peng, Cheng
;
Behnisch, Thomas
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/05
hippocampus
eEF2 kinase
protein synthesis
learning
memory
synaptic plasticity
oxygen
Phf8 histone demethylase deficiency causes cognitive impairments through the mTOR pathway
期刊论文
NATURE COMMUNICATIONS, 2018, 卷号: 9, 期号: 1, 页码: 114
作者:
Chen, Xuemei
;
Wang, Shuai
;
Zhou, Ying
;
Han, Yanfei
;
Li, Shengtian
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/04/28
Linked Mental-retardation
Cleft lip/Cleft Palate
Synaptic Plasticity
Protein-synthesis
Cell-cycle
Gene
Mutations
Memory
Identification
Differentiation
Correcting miR92a-vGAT-Mediated GABAergic Dysfunctions Rescues Human Tau-Induced Anxiety in Mice
期刊论文
MOLECULAR THERAPY, 2017, 卷号: 25, 期号: 1, 页码: 140-152
作者:
Li, Xiaoguang
;
Wang, Zhihao
;
Tan, Lu
;
Wang, Yali
;
Lu, Chengbiao
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  |  
浏览/下载:26/0
  |  
提交时间:2017/03/16
Regulation of mTORC1 signaling network underlying the pathophysiology and treatment of depression: new insights for rapid-acting antidepressants
期刊论文
2017, 卷号: 38, 期号: 7, 页码: 1071-1071
作者:
Zeng, Ting
;
Wang, Zhen-zhen
;
Chen, Nai-hong
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/04
depression
antidepressant
mammalian Target of Rapamycin Complex 1 (mTORC1) signaling network
alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor
ketamine
brain-derived neurotrophic factor (BDNF)
synaptic protein synthesis
eukaryotic elongation factor 2 (eEF2)
autophagy
Potentiation of Schaffer-Collateral CA1 Synaptic Transmission by eEF2K and p38 MAPK Mediated Mechanisms
期刊论文
FRONTIERS IN CELLULAR NEUROSCIENCE, 2016, 卷号: 10
作者:
Weng, Weiguang
;
Chen, Ying
;
Wang, Man
;
Zhuang, Yinghan
;
Behnisch, Thomas
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
hippocampus
protein synthesis
memory
synaptic plasticity
eEF2
MAPK
oscillation
Inhibition of Lactate Transport Erases Drug Memory and Prevents Drug Relapse
期刊论文
BIOLOGICAL PSYCHIATRY, 2016
Zhang, Yan
;
Xue, Yanxue
;
Meng, Shiqiu
;
Luo, Yixiao
;
Liang, Jie
;
Li, Jiali
;
Ai, Sizhi
;
Sun, Chengyu
;
Shen, Haowei
;
Zhu, Weili
;
Wu, Ping
;
Lu, Lin
;
Shi, Jie
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/12/03
Basolateral amygdale
Cocaine
Lactate transport
Reconsolidation
Relapse
Retrieval
LOCAL PROTEIN-SYNTHESIS
NUCLEUS-ACCUMBENS CORE
FOOTSHOCK-INDUCED REINSTATEMENT
CONDITIONED PLACE PREFERENCE
COCAINE-SEEKING BEHAVIOR
D-SERINE
BASOLATERAL AMYGDALA
MONOCARBOXYLATE TRANSPORTERS
SYNAPTIC PLASTICITY
SIGNALING PATHWAY
AMPK Signaling in the Dorsal Hippocampus Negatively Regulates Contextual Fear Memory Formation
期刊论文
NEUROPSYCHOPHARMACOLOGY, 2016
Han, Ying
;
Luo, Yixiao
;
Sun, Jia
;
Ding, Zengbo
;
Liu, Jianfeng
;
Yan, Wei
;
Jian, Min
;
Xue, Yanxue
;
Shi, Jie
;
Wang, Ji-Shi
;
Lu, Lin
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/12/03
AMPK
fear memory
formation
mTORC1
ACTIVATED PROTEIN-KINASE
ANTERIOR CINGULATE CORTEX
SURFACE EXPRESSION
SPATIAL MEMORY
TRANSLATIONAL CONTROL
SYNAPTIC PLASTICITY
ALZHEIMERS-DISEASE
RAPAMYCIN PATHWAY
MAMMALIAN TARGET
PYRAMIDAL CELLS
What are the biological roots of sexual orientation?
期刊论文
Kexue Tongbao/Chinese Science Bulletin, 2016
Shen, Zheng
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2017/12/04
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