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上海药物研究所 [25]
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CircVAPA promotes small cell lung cancer progression by modulating the miR-377-3p and miR-494-3p/IGF1R/AKT axis
期刊论文
Molecular Cancer, 2022, 卷号: 21
作者:
Hua,Jinghan
;
Wang,Xiaolin
;
Ma,Liying
;
Li,Jingxin
;
Cao,Guozhen
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/12/22
CircVAPA
SCLC
Progression
miR-377-3p
miR-494-3p
IGF1R
AKT
BMS-536924
Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9
作者:
Liu, Xiao
;
Yang, Su
;
Hart, Jonathan R.
;
Xu, Yingna
;
Zou, Xinyu
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/01/04
phosphoinositide 3-kinase (PI3K)
activation
inhibition
activity-dependent conformational changes
Adaptive resistance to PI3K alpha-selective inhibitor CYH33 is mediated by genomic and transcriptomic alterations in ESCC cells
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 1, 页码: 13
作者:
Wang, Yu-xiang
;
Zhang, Xu
;
Ma, Qing-yang
;
Hu, Lan-dian
;
Zhang, Xi
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
Endosulfan promotes cell migration via PTP4A3-mediated signaling pathways in HUVECs
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 192, 页码: 1-9
作者:
Li, Heng
;
Liu, Shiqi
;
Hu, Yumeng
;
Zhao, Bin
;
Sun, Yeqing
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/09/14
Endosulfan
Cell migration
PTP4A3
Signaling pathway
Endothelial cells
B591, a novel specific pan-PI3K inhibitor, preferentially targets cancer stem cells
期刊论文
ONCOGENE, 2019, 卷号: 38, 期号: 18, 页码: 3371-3386
作者:
Zhou, Hongyu
;
Yu, Chunlei
;
Kong, Lingmei
;
Xu, Xiaoliang
;
Yan, Juming
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  |  
浏览/下载:191/0
  |  
提交时间:2019/06/24
BOS-93, a novel bromophenol derivative, induces apoptosis and autophagy in human A549 lung cancer cells via PI3K/Akt/mTOR and MAPK signaling pathway
期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2019, 卷号: 17, 期号: 5, 页码: 3848-3858
作者:
Guo, Chuanlong
;
Wang, Lijun
;
Zhao, Yue
;
Jiang, Bo
;
Luo, Jiao
收藏
  |  
浏览/下载:117/0
  |  
提交时间:2019/08/28
bromophenol
apoptosis
autophagy
phosphoinositide 3-kinase
protein kinase B
mechanistic target of rapamycin signaling
reactive oxygen species
Colletotrichine B, a new sesquiterpenoid from Colletotrichum gloeosporioides GT-7, a fungal endophyte of Uncaria rhynchophylla
期刊论文
NATURAL PRODUCT RESEARCH, 2019, 卷号: 33, 期号: 1, 页码: 108-112
作者:
Chen, Xiao-Wei
;
Yang, Zhong-Duo
;
Li, Xiao-Fei
;
Sun, Jian-Hui
;
Yang, Li-Jun
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/11/15
Colletotrichum gloeosporioides
sesquiterpenoid
Uncaria rhynchophylla
acetylcholinesterase inhibitor
PI3K alpha inhibitor
Colletotrichine B, a new sesquiterpenoid from Colletotrichum gloeosporioides GT-7, a fungal endophyte of Uncaria rhynchophylla
期刊论文
NATURAL PRODUCT RESEARCH, 2019, 卷号: 33, 期号: 1, 页码: 108-112
作者:
Chen, Xiao-Wei
;
Yang, Zhong-Duo
;
Li, Xiao-Fei
;
Sun, Jian-Hui
;
Yang, Li-Jun
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2022/03/01
Colletotrichum gloeosporioides
sesquiterpenoid
Uncaria rhynchophylla
acetylcholinesterase inhibitor
PI3K alpha inhibitor
The PI3K inhibitor buparlisib suppresses osteoclast formation and tumour cell growth in bone metastasis of lung cancer, as evidenced by multimodality molecular imaging
期刊论文
ONCOLOGY REPORTS, 2019, 卷号: 41, 期号: 5
作者:
Wang, Shengfei
;
Niu, Xiaomin
;
Bao, Xiao
;
Wang, Qin
;
Zhang, Jianping
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/12/05
non-small cell lung cancer
bone metastasis
phosphoinositide-3-kinase inhibitor
multimodality molecular imaging
multiparametric quantification
The PI3K inhibitor buparlisib suppresses osteoclast formation and tumour cell growth in bone metastasis of lung cancer, as evidenced by multimodality molecular imaging
期刊论文
ONCOLOGY REPORTS, 2019, 卷号: 41, 期号: 5
作者:
Wang, Qin
;
Zhang, Jianping
;
Lu, Shun
;
Wang, Yongjun
;
Xu, Ling
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
non-small cell lung cancer
bone metastasis
phosphoinositide-3-kinase inhibitor
multimodality molecular imaging
multiparametric quantification
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