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化学研究所 [12]
上海药物研究所 [11]
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中国农业科学院 [3]
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期刊论文 [44]
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Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13
作者:
Meng, Xiang-Dong
;
Gao, Li-Xin
;
Wang, Zhi-Jia
;
Feng, Bo
;
Zhang, Chun
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/12/01
2,5-diphenyl-1,3,4-oxadiazole derivatives
SHP2
Inhibitors
Structure-activity relationships (SAR)
Capsaicin derivatives with nitrothiophene substituents: Design, synthesis and antibacterial activity against multidrug-resistant S. aureus
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 198, 页码: 11
作者:
Wang, Zhi-Cheng
;
Wei, Bingyan
;
Pei, Fang-Ning
;
Yang, Teng
;
Tang, Jie
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  |  
浏览/下载:12/0
  |  
提交时间:2020/12/24
Capsaicin
Nitrothiophene
Multidrug-resistant S. aureus
Antibacterial agent
Design, synthesis, and biological evaluation of 1,2,5-oxadiazole-3-carboximidamide derivatives as novel indoleamine-2,3-dioxygenase 1 inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 189, 页码: 14
作者:
Song, Xiaohan
;
Sun, Pu
;
Wang, Jiang
;
Guo, Wei
;
Wang, Yi
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  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
IDO1 inhibitors
Immunotherapy
Anti-Tumor
Design, synthesis and antitumor study of a series of N-Cyclic sulfamoylaminoethyl substituted 1,2,5-oxadiazol-3-amines as new indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 179, 页码: 38-55
作者:
Chen, Shulun
;
Guo, Wei
;
Liu, Xiaohua
;
Sun, Pu
;
Wang, Yi
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  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
Indoleamine 2,3-dioxygenase
Immunotherapy
Oxadiazole
PD-1
Life span
Design, synthesis, and fungicidal activity of novel 1,3,4-oxadiazole derivatives
期刊论文
CHINESE CHEMICAL LETTERS, 2018, 卷号: 29, 期号: 6, 页码: 915-918
作者:
Yu Fuqiang
;
Guan Aiying
;
Li Mengru
;
Hu Lan
;
Li Xiaowu
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  |  
浏览/下载:9/0
  |  
提交时间:2021/02/02
INSECTICIDAL ACTIVITIES
SAR
1,3,4-Oxadiazole derivatives
Intermediate derivatization method
Rice sheath blight
Sorghum anthracnose
Structure-activity relationship
Design, synthesis, and fungicidal activity of novel 1,3,4-oxadiazole derivatives
期刊论文
CHINESE CHEMICAL LETTERS, 2018, 卷号: 29, 期号: 6, 页码: 915-918
作者:
Yu Fuqiang
;
Guan Aiying
;
Li Mengru
;
Hu Lan
;
Li Xiaowu
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2021/02/02
INSECTICIDAL ACTIVITIES
SAR
1,3,4-Oxadiazole derivatives
Intermediate derivatization method
Rice sheath blight
Sorghum anthracnose
Structure-activity relationship
Synthesis and biological evaluation of benzothiazol-based 1,3,4-oxadiazole derivatives as amyloid beta-targeted compounds against Alzheimer's disease
期刊论文
MONATSHEFTE FUR CHEMIE, 2017, 卷号: 148, 期号: 10, 页码: 1807-1815
作者:
Mei, Wen-wen
;
Ji, Sha-sha
;
Xiao, Wei
;
Wang, Xue-dong
;
Jiang, Cheng-shi
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  |  
浏览/下载:62/0
  |  
提交时间:2019/01/08
Structure-activity relationships
Heterocycles
Drug research
Neuroprotective effects
Discovery of 4-chloro-3-(5-(pyridin-3-yl)-1,2,4-oxadiazole-3-yl) benzamides as novel RET kinase inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 23, 页码: 5679-5684
作者:
Han, Mei
;
Li, Shan
;
Ai, Jing
;
Sheng, Rong
;
Hu, Yongzhou
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
RET kinase inhibitor
1,2,4-Oxadiazole
Anti-cancer therapy
Synthesis and Protein-Tyrosine Phosphatase 1B Inhibitory Activity Evaluation of Indolepropyl Based 1,3,4-Oxadiazole Derivatives
期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2016, 卷号: 36, 期号: 3, 页码: 533-539
作者:
Mei Wenweeb
;
Guo Yuewei
;
Li Jia
;
Cai Meiyi
;
Ma Wenquan
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
1,3,4-oxadiazole
synthesis
PTP1B inhibitory activity
Synthesis, Crystal Structure and Antifungal Activity of 2-((2-Fluorobenzyl)thio)-5-(pyridin-4-yl)-1,3,4-oxadiazole
期刊论文
CHINESE JOURNAL OF STRUCTURAL CHEMISTRY, 2016, 卷号: 35, 期号: 12, 页码: 1855-1859
作者:
Sun Guo-Xiang
;
Shi Yan-Xia
;
Zhai Zhi-Wen
;
Sun Zhao-Hui
;
Weng Jian-Quan
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2017/05/03
oxadiazole compound
synthesis
crystal structure
antifungal activity
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