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cKMT1 is a New Lysine Methyltransferase That Methylates the Ferredoxin-NADP(+) Oxidoreductase and Regulates Energy Transfer in Cyanobacteria 期刊论文
MOLECULAR & CELLULAR PROTEOMICS, 2023, 卷号: 22, 期号: 4, 页码: 20
作者:  Cao, Gaoxiang;  Lin, Xiaohuang;  Ling, Mingtian;  Lin, Jian;  Zhang, Qi
收藏  |  浏览/下载:1/0  |  提交时间:2024/05/07
Inhibition of the deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2 期刊论文
LEUKEMIA, 2022
作者:  Yang, Jing;  Weisberg, Ellen L.;  Qi, Shuang;  Ni, Wei;  Mei, Husheng
收藏  |  浏览/下载:76/0  |  提交时间:2022/02/14
5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19
作者:  Wang, Shuni;  Yang, Hong;  Su, Mingbo;  Lian, Fulin;  Cong, Zhanqing
收藏  |  浏览/下载:80/0  |  提交时间:2021/11/04
Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207
作者:  Du, Daohai;  Xu, Dandan;  Zhu, Licheng;  Stazi, Giulia;  Zwergel, Clemens
收藏  |  浏览/下载:74/0  |  提交时间:2021/08/17
Ube2b-dependent degradation of DNMT3a relieves a transcriptional brake on opiate-induced synaptic and behavioral plasticity 期刊论文
MOLECULAR PSYCHIATRY, 2021, 卷号: 26, 期号: 4, 页码: 1162-1177
作者:  Chen, Zhong-Guo;  Wang, Yu-Jun;  Chen, Ruo-Song;  Geng, Fan;  Gan, Chen-Ling
收藏  |  浏览/下载:18/0  |  提交时间:2021/05/24
Synthesis and structure-activity relationship studies of LLY-507 analogues as SMYD2 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 5
作者:  Zhang, Bin;  Liao, Liping;  Wu, Fan;  Zhang, Fengcai;  Sun, Zhongya
收藏  |  浏览/下载:34/0  |  提交时间:2021/05/24
The cross-talk between methylation and phosphorylation in lymphoid-specific helicase drives cancer stem-like properties 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 卷号: 5, 期号: 1, 页码: 14
作者:  Liu, Na;  Yang, Rui;  Shi, Ying;  Chen, Ling;  Liu, Yating
收藏  |  浏览/下载:34/0  |  提交时间:2020/12/21
Identification of catalytic and non-catalytic activity inhibitors against PRC2-EZH2 complex through multiple high-throughput screening campaigns 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 页码: 27
作者:  Zhou, Yan;  Du, Dao-Hai;  Wang, Jia;  Cai, Xiao-Qing;  Deng, Alicia X.
收藏  |  浏览/下载:102/0  |  提交时间:2020/07/01
Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 9, 页码: 10
作者:  Hou, Zeng;  Min, Wenjian;  Zhang, Rukang
收藏  |  浏览/下载:43/0  |  提交时间:2020/07/01
Computational discovery and biological evaluation of novel inhibitors targeting histone-lysine N-methyltransferase SET7 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 7, 页码: 10
作者:  Min, Wenjian;  Hou, Zeng;  Zhang, Fang;  Xie, Shengnan;  Yuan, Kai
收藏  |  浏览/下载:49/0  |  提交时间:2020/07/01


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