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山东大学 [11]
复旦大学上海医学院 [11]
上海药物研究所 [10]
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Genomic characterization reveals distinct mutation landscapes and therapeutic implications in neuroendocrine carcinomas of the gastrointestinal tract
期刊论文
CANCER COMMUNICATIONS, 2022
作者:
Wu, Huanwen
;
Yu, Zicheng
;
Liu, Yueping
;
Guo, Lei
;
Teng, Lianghong
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/12/22
Neuroendocrine carcinomas
Gastrointestinal tract
Genomic characterization
Heterogeneity
Therapeutic implications
Transcriptomic and metabonomic analyses reveal roles of VPS 29 in carotenoid accumulation in adductor muscles of QN Orange scallops
期刊论文
GENOMICS, 2021, 卷号: 113, 期号: 4, 页码: 2839-2846
作者:
Song, Junlin
;
Wang, Chunde
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/10/21
Transcriptomic
VPS29
Carotenoid deposition
mRNA
Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia
期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1216-1230
作者:
Wu, Chenglin
;
Xi, Cong
;
Tong, Junhua
;
Zhao, Jing
;
Jiang, Hualiang
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/07/01
PCSK9
Tetrahydroprotoberberine derivatives
Low-density lipoprotein cholesterol
Lipid-lowering
PCSK9 expression
Low-density lipoprotein receptor
Total cholesterol
Hyperlipidemia hamster
Deficiency of lrp4 in zebrafish and human LRP4 mutation induce aberrant activation of Jagged-Notch signaling in fin and limb development
期刊论文
CELLULAR AND MOLECULAR LIFE SCIENCES, 2019, 卷号: 76, 期号: 1, 页码: 163-178
作者:
Tian, Jing
;
Shao, Jinhui
;
Liu, Cong
;
Hou, Hsin-Yu
;
Chou, Chih-Wei
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2019/07/01
Skeletogenesis
Bone disorders
Pronephros
Morphant
Phenocopy
EGF-like domain
wt1b
HES1
LRP5 controls cardiac QT interval by modulating the metabolic homeostasis of L-type calcium channel
期刊论文
International Journal of Cardiology, 2019, 卷号: Vol.275, 页码: 120-128
作者:
Dandan Liang
;
Yahan Wu
;
Liping Zhou
;
Yongli Chen
;
Hongyu Liu
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/12/13
Low-density
lipoprotein
receptor-related
protein
QT
interval
Action
potential
duration
Myocyte
L-type
calcium
channel
Proteasomal
degradation
The role of low density lipoprotein receptor-related protein 11 as a tumor promoter in cervical cancer
期刊论文
CANCER MANAGEMENT AND RESEARCH, 2019, 卷号: 11, 页码: 8081-8093
作者:
Wang, Ying
;
Han, Sai
;
You, Xuewu
;
Shi, Xuejiao
;
Liu, Lu
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/11
HPV
cervical cancer
LRP11
P16
cell cycle
Low-Density Lipoprotein Receptor-Related Protein 6 Is Essential for Trophoblast Survival and Invasion
期刊论文
REPRODUCTIVE SCIENCES, 2019, 卷号: 26, 期号: 1, 页码: 35-43
作者:
Li, Lei
;
Wan, Jipeng
;
Xue, Jing
;
Li, Hongyan
;
Wang, Shan
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/11
low-density lipoprotein
low-density lipoprotein receptor-related
protein 6
spiral artery remodeling
trophoblast
angiogenesis
LRP5 controls cardiac QT interval by modulating the metabolic homeostasis of L-type calcium channel
期刊论文
INTERNATIONAL JOURNAL OF CARDIOLOGY, 2019, 卷号: Vol.275, 页码: 120-128
作者:
Liang, Dandan
;
Wu, Yahan
;
Zhou, Liping
;
Chen, Yongli
;
Liu, Hongyu
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/12/17
Low-density
lipoprotein
receptor-related
protein
QT
interval
Action
potential
duration
Myocyte
L-type
calcium
channel
Proteasomal
degradation
designsynthesisandbiologicalevaluationofnoveltetrahydroprotoberberinederivativesthpbsasproproteinconvertasesubtilisinkexintype9pcsk9modulatorsforthetreatmentofhyperlipidemia
期刊论文
actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 6, 页码: 1216
作者:
Wu Chenglin
;
Xi Cong
;
Tong Junhua
;
Zhao Jing
;
Jiang Hualiang
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2020/07/01
DOPAMINE D-1
BERBERINE
EXPRESSION
INHIBITORS
IDENTIFICATION
CHOLESTEROL
MUTATIONS
LDLR
PCSK9
Tetrahydroprotoberberine derivatives
Low-density lipoprotein cholesterol
Lipid-lowering
PCSK9 expression
Low-density lipoprotein receptor
Total cholesterol
Hyperlipidemia hamster
Adenosine Monophosphate - Activated Protein Kinase Signaling Regulates Lipid Metabolism in Response to Salinity Stress in the Red-Eared Slider Turtle Trachemys scripta elegans
期刊论文
FRONTIERS IN PHYSIOLOGY, 2019, 卷号: 10, 页码: 962
作者:
Hong, Meiling
;
Li, Na
;
Li, Jiangyue
;
Li, Weihao
;
Liang, Lingyue
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/11/04
Trachemys scripta elegans
salinity adaptation
fatty acid oxidation
lipid synthesis
lipid metabolism-related transcription factors
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