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上海生物化学与细胞... [21]
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期刊论文 [47]
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The methyltransferase METTL3 negatively regulates nonalcoholic steatohepatitis (NASH) progression
期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 17
作者:
Li, Xinzhi
;
Yuan, Bingchuan
;
Lu, Min
;
Wang, Yuqin
;
Ding, Na
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/01/18
Berberine promotes the recruitment and activation of brown adipose tissue in mice and humans
期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 18
作者:
Wu, Lingyan
;
Xia, Mingfeng
;
Duan, Yanan
;
Zhang, Lina
;
Jiang, Haowen
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
Targeting PRMT5 Activity Inhibits the Malignancy of Hepatocellular Carcinoma by Promoting the Transcription of HNF4 alpha
期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 9, 页码: 2606-2617
作者:
Zheng, Bai-Nan
;
Ding, Chen-Hong
;
Chen, Shi-Jie
;
Zhu, Kongkai
;
Shao, Jingwei
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/07/01
PRMT5
HNF4 alpha
hepatocellular carcinoma
cancer stem cells
HS218 as an FXR antagonist suppresses gluconeogenesis by inhibiting FXR binding to PGC-1 alpha promoter
期刊论文
METABOLISM-CLINICAL AND EXPERIMENTAL, 2018, 卷号: 85, 页码: 126-138
作者:
Xu, Xin
;
Shi, Xiaofan
;
Chen, Yidi
;
Zhou, Tingting
;
Wang, Jiaying
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/07/01
T2DM
Gluconeogenesis
FXR antagonist
PGC-1 alpha
Drug lead compound
Aberrant GSTP1 promoter methylation predicts poor prognosis of acute-on-chronic hepatitis B pre-liver failure
期刊论文
CLINICAL AND EXPERIMENTAL MEDICINE, 2018, 卷号: 18, 期号: 1, 页码: 51-62
作者:
Qiao, Chen-Yang
;
Li, Feng
;
Teng, Yue
;
Zhao, Jing
;
Hu, Na
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
Acute-on-chronic hepatitis B pre-liver failure
DNA methylation
Glutathione-S-transferase P1
Methylation-specific polymerase chain
reaction
Prognosis
Construction of minicircle DNA vectors capable of correcting familial hypercholesterolemia phenotype in a LDLR-deficient mouse model
期刊论文
Gene Therapy , 2016
作者:
Hou, X
;
Jiao, R
;
Guo, X
;
Wang, T
;
Chen, P
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2017/01/16
Phosphorylation of PPAR gamma at Ser84 promotes glycolysis and cell proliferation in hepatocellular carcinoma by targeting PFKFB4
期刊论文
Oncotarget, 2016
Shu, Yuxin
;
Lu, Yan
;
Pang, Xiaojuan
;
Zheng, Wei
;
Huang, Yahong
;
Li, Jiahong
;
Ji, Jianguo
;
Zhang, Can
;
Shen, Pingping
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2017/12/03
phosphorylation
PPAR gamma
PFKFB4
hepatocellular carcinoma
glycolysis
ACTIVATED PROTEIN-KINASE
LIVER-CANCER
RECEPTOR-GAMMA
TUMOR-GROWTH
MOUSE MODEL
METABOLISM
INHIBITOR
HYPOXIA
DYSREGULATION
ADIPOGENESIS
Human-Specific Hypomethylation of CENPJ, a Key Brain Size Regulator
期刊论文
MOLECULAR BIOLOGY AND EVOLUTION, 2016, 卷号: 31, 期号: 3, 页码: 594-604
作者:
Shi L
;
Lin Q
;
Su B[*]
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2014/04/11
DNA methylation
CENPJ
brain evolution
primate
CpG island
epigenetic regulation
Gene Therapy for Hemophilia B With Liver-specific Element Mediated by Rep-RBE Site-specific Integration System
期刊论文
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2015, 卷号: 65, 期号: 2
作者:
Xu, Zhengxin
;
Ye, Juan
;
Zhang, Amin
;
Xie, Linjun
;
Shen, Qi
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/13
hFIX
RBE
liver-specific promoter
AAVS1 transgenic mice
gene therapy
MG132, a proteasome inhibitor, enhances LDL uptake in HepG2 cells in vitro by regulating LDLR and PCSK9 expression
期刊论文
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 8, 页码: 994-1004
作者:
Yan, Hong
;
Ma, Yan-ling
;
Gui, Yu-zhou
;
Wang, Shu-mei
;
Wang, Xin-bo
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
cholesterol homeostasis
LDLR
MG132
proteasome inhibition
PKC
PCSK9
pravastatin
HepG2
cells
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