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科研机构
合肥物质科学研究院 [18]
上海药物研究所 [15]
复旦大学上海医学院 [7]
中国医学科学院 北京... [3]
北京大学 [2]
湖南大学 [2]
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期刊论文 [47]
会议论文 [3]
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2022 [1]
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Zanubrutinib monotherapy for relapsed or refractory non-germinal center diffuse large B-cell lymphoma
期刊论文
BLOOD ADVANCES, 2022, 卷号: 6
作者:
Yang, Haiyan
;
Xiang, Bing
;
Song, Yuqin
;
Zhang, Huilai
;
Zhao, Weili
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/12/23
Identification of Novel Fused Heteroaromatics-Based MALT1 Inhibitors by High-Throughput Screening to Treat B Cell Lymphoma
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 13, 页码: 9217-9237
作者:
Liang, Xuewu
;
Sun, Chenxia
;
Li, Chunpu
;
Yu, Haolan
;
Wei, Xiaohui
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/08/17
Bruton's tyrosine kinase inhibitors in primary central nervous system lymphoma-evaluation of anti-tumor efficacy and brain distribution
期刊论文
TRANSLATIONAL CANCER RESEARCH, 2021, 卷号: 10
作者:
Yu, Haifeng
;
Kong, Haiying
;
Li, Cong
;
Dong, Xiaowu
;
Wu, Yizhe
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  |  
浏览/下载:24/0
  |  
提交时间:2021/08/31
Primary central nervous system lymphoma ( PCNSL)
Bruton's tyrosine kinase (BTK)
ibrutinib
zanubrutinib
tirabrutinib
A novel tricyclic BTK inhibitor suppresses B cell responses and osteoclastic bone erosion in rheumatoid arthritis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Liu, Yu-ting
;
Ding, Hui-hua
;
Lin, Ze-min
;
Wang, Que
;
Chen, Li
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/05/24
rheumatoid arthritis
BTK inhibitors
B cells
macrophages
RANKL
osteoclastogenesis
Inhibition of B-cell receptor signaling disrupts cell adhesion in mantle cell lymphoma via RAC2
期刊论文
BLOOD ADVANCES, 2021, 卷号: 5, 期号: 1, 页码: 185-197
作者:
Wu, Wenjun
;
Wang, Weige
;
Franzen, Carrie A.
;
Guo, Hui
;
Lee, Jimmy
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  |  
浏览/下载:42/0
  |  
提交时间:2020/07/01
Characterization of covalent binding of tyrosine kinase inhibitors to plasma proteins
期刊论文
DRUG METABOLISM AND PHARMACOKINETICS, 2020, 卷号: 35, 期号: 5, 页码: 456-465
作者:
Liu, Xiaoyun
;
Feng, Dan
;
Zheng, Mingyue
;
Cui, Yongmei
;
Zhong, Dafang
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/12/21
Covalent tyrosine kinase inhibitors
Covalent binding
Human serum albumin
Molecular docking
Quantitative calculations
Linear modeling
Species difference
Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Zhang, Xiao-tuan
;
Hu, Xiao-bei
;
Wang, Han-lin
;
Kan, Wei-juan
;
Xu, Lei
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  |  
浏览/下载:47/0
  |  
提交时间:2020/12/24
DLBCL
BTK inhibitor
ibrutinib resistance
UPR
TUDCA
2-DG
Design and synthesis of Imidazo[1,2-b]pyridazine IRAK4 inhibitors for the treatment of mutant MYD88 L265P diffuse large B-cell lymphoma
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 190, 页码: 14
作者:
Chen, Yun
;
Bai, Gang
;
Ning, Yi
;
Cai, Shi
;
Zhang, Tao
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
lnterleukin-1 receptor associated kinase 4
Imidazol1,2-6]pyridazine
Diffuse large B-cell lymphoma
Drug design
Antitumor agents
Discovery and biological evaluation of N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide as potent Bruton's tyrosine kinase inhibitors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 415-422
作者:
Lai, Meng-zhen
;
Song, Pei-ran
;
Dou, Dou
;
Diao, Yan-yan
;
Tong, Lin-jiang
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
B cell receptor
Bruton's tyrosine kinase
ibrutinib
small-molecule inhibitor
B cell malignancies
Diffuse large B-cell lymphoma with low F-18-fluorodeoxyglucose avidity features silent B-cell receptor signaling
期刊论文
LEUKEMIA & LYMPHOMA, 2020, 页码: 8
作者:
Sheng, Dong
;
Li, Ting
;
Wang, Wei-Ge
;
Li, Meng-Jiao
;
Jiang, Kai-Long
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
Diffuse large B-cell lymphoma
PET
CT
B-cell receptor signaling
pSYK
GLUT1
HK2
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