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CORC

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TWIRLS, a knowledge-mining technology, suggests a possible mechanism for the pathological changes in the human host after coronavirus infection via ACE2 (vol 81, pg 1004, 2020) 期刊论文
DRUG DEVELOPMENT RESEARCH, 2021, 页码: 1
作者:  Niu, Gang
收藏  |  浏览/下载：24/0  |  提交时间：2021/12/01
TWIRLS, a knowledge-mining technology, suggests a possible mechanism for the pathological changes in the human host after coronavirus infection via ACE2 期刊论文
DRUG DEVELOPMENT RESEARCH, 2020, 卷号: 81, 期号: 8, 页码: 1004-1018
作者:  Ji, Xiaoyang;  Tan, Wenting;  Zhang, Chunming;  Zhai, Yubo;  Hsueh, Yiching
收藏  |  浏览/下载：46/0  |  提交时间：2021/12/01
Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7
作者:  Bi, Xiaoyang;  Chen, Yu;  Sun, Zhongya;  Lu, Wenchao;  Xu, Pan
收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24
Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 13
作者:  Wang, Zheng;  Li, Zeng-xia;  Zhao, Wen-cao;  Huang, Hong-bo;  Wang, Jia-qi
收藏  |  浏览/下载：82/0  |  提交时间：2020/12/24
Discovery of Highly Potent, Selective, and Orally Efficacious p300/CBP Histone Acetyltransferases Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 3, 页码: 1337-1360
作者:  
收藏  |  浏览/下载：40/0  |  提交时间：2020/07/01
An acute lytic cell death induced by xanthohumol obstructed ROS detecting in HL-60 cells 期刊论文
TOXICOLOGY IN VITRO, 2020, 卷号: 62, 页码: 7
作者:  Wang, Chun-Ming;  Huo, Xiang;  Chen, Jun;  Liu, Jia-Wei;  Yang, Ting-Yu
收藏  |  浏览/下载：16/0  |  提交时间：2022/01/19
Licochalcone A suppresses the proliferation of sarcoma HT-1080 cells, as a selective R132C mutant IDH1 inhibitor 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 5
作者:  Hu, Chujiao;  Zuo, Yu;  Liu, Jingqiu;  Xu, Heng;  Liao, Weike
收藏  |  浏览/下载：37/0  |  提交时间：2020/07/01
The Development of Inhibitors Targeting the Mixed Lineage Leukemia 1 (MLL1)-WD Repeat Domain 5 Protein (WDR5) Protein-Protein Interaction 期刊论文
CURRENT MEDICINAL CHEMISTRY, 2020, 卷号: 27, 期号: 33, 页码: 5530-5542
作者:  Ye, Xiaoqing;  Chen, Gang;  Jin, Jia;  Zhang, Binzhong;  Wang, Yinda
收藏  |  浏览/下载：14/0  |  提交时间：2020/12/24
Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia 期刊论文
CANCER CELL, 2019, 卷号: 35, 期号: 4, 页码: 677-+
作者:  Huang, Yue;  Su, Rui;  Sheng, Yue;  Dong, Lei;  Dong, Ze
收藏  |  浏览/下载：25/0  |  提交时间：2020/07/01
The combination of Nutlin-3 and Tanshinone IIA promotes synergistic cytotoxicity in acute leukemic cells expressing wild-type p53 by co-regulating MDM2-P53 and the AKT/mTOR pathway 期刊论文
The International Journal of Biochemistry & Cell Biology, 2019, 卷号: Vol.106, 页码: 8-20
作者:  Yong Guo;  Yi Li;  Fang-Fang Wang;  Bing Xiang;  Xiao-Ou Huang
收藏  |  浏览/下载：8/0  |  提交时间：2019/02/28

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