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科研机构
上海药物研究所 [10]
大连化学物理研究所 [2]
江苏大学 [1]
内容类型
期刊论文 [12]
会议论文 [1]
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2016 [2]
2015 [4]
2013 [2]
2012 [2]
2011 [1]
2009 [2]
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物理化学 [1]
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Pharmacokinetics and Disposition of Circulating Iridoids and Organic Acids in Rats Intravenously Receiving ReDuNing Injection
期刊论文
DRUG METABOLISM AND DISPOSITION, 2016, 卷号: 44, 期号: 11, 页码: 1853-1858
作者:
Cheng, Chen
;
Du, Feifei
;
Yu, Ke
;
Xu, Fang
;
Wang, Fengqing
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
Optimized Hepatocyte-Like Cells with Functional Drug Transporters Directly-Reprogrammed from Mouse Fibroblasts and their Potential in Drug Disposition and Toxicology
期刊论文
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2016, 卷号: 38, 期号: 5, 页码: 1815-1830
作者:
Wu, Zhi-Tao
;
Yao, Dan
;
Ji, Shu-Yi
;
Ni, Xuan
;
Gao, Yi-Meng
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Direct reprogramming
Hepatocyte-like cells
Hepatic transporters
Biliary clearances
Cholestasis
Fasiglifam (TAK-875) Inhibits Hepatobiliary Transporters: A Possible Factor Contributing to Fasiglifam-Induced Liver Injury
期刊论文
Drug metabolism and disposition: the biological fate of chemicals, 2015, 卷号: 43, 期号: 11, 页码: 1751-9
作者:
Li, Xiuli
;
Zhong, Kan
;
Guo, Zitao
;
Zhong, Dafang
;
Chen, Xiaoyan
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
Systemic Exposure to and Disposition of Catechols Derived from Salvia miltiorrhiza Roots (Danshen) after Intravenous Dosing DanHong Injection in Human Subjects, Rats, and Dogs
期刊论文
DRUG METABOLISM AND DISPOSITION, 2015, 卷号: 43, 期号: 5, 页码: 679-690
作者:
Li, Meijuan
;
Wang, Fengqing
;
Huang, Yuhong
;
Du, Feifei
;
Zhong, Chenchun
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
The Hepatobiliary Disposition of Timosaponin B2 Is Highly Dependent on Influx/Efflux Transporters but Not Metabolism
期刊论文
DRUG METABOLISM AND DISPOSITION, 2015, 卷号: 43, 期号: 1, 页码: 63-72
作者:
Sheng, Jingjing[1]
;
Tian, Xiaoting[2]
;
Xu, Guanglin[3]
;
Wu, Zhitao[4]
;
Chen, Chen[5]
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/24
The Hepatobiliary Disposition of Timosaponin B2 Is Highly Dependent on Influx/Efflux Transporters but Not Metabolism
期刊论文
DRUG METABOLISM AND DISPOSITION, 2015, 卷号: 43, 期号: 1, 页码: 63-72
作者:
Sheng, Jingjing
;
Tian, Xiaoting
;
Xu, Guanglin
;
Wu, Zhitao
;
Chen, Chen
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/01/08
Stereoselective Glucuronidation of Ornidazole in Humans: Predominant Contribution of UDP-Glucuronosyltransferases 1A9 and 2B7
期刊论文
DRUG METABOLISM AND DISPOSITION, 2013, 卷号: 41, 期号: 7, 页码: 1306-1318
作者:
Du, Jiangbo
;
You, Tiangeng
;
Chen, Xiaoyan
;
Zhong, Dafang
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Effects of glucose and insulin on expression and function of bile acid transporters in sandwich cultured rat hepatocytes
期刊论文
Chinese Journal of Clinical Pharmacology and Therapeutics, 2013, 卷号: 18, 期号: 8, 页码: 847-852
作者:
He Lei
;
Guo Cen
;
Yao Dan
;
Sheng Jingjing
;
Pan Guoyu
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Glucose
Insulin
Sandwich cultured rat hepatocyte
Bile acid transporter
Absorption, Disposition, and Pharmacokinetics of Saponins from Chinese Medicinal Herbs: What Do We Know and What Do We Need to Know More?
期刊论文
CURRENT DRUG METABOLISM, 2012, 卷号: 13, 期号: 5, 页码: 577-598
作者:
Yu, Ke
;
Chen, Feng
;
Li, Chuan
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Panax
ginsenoside
saponin
absorption
disposition
Assessment of Biliary Clearance in Early Drug Discovery Using Sandwich-Cultured Hepatocyte Model
期刊论文
JOURNAL OF PHARMACEUTICAL SCIENCES, 2012, 卷号: 101, 期号: 5, 页码: 1898-1908
作者:
Pan, Guoyu
;
Boiselle, Carri
;
Wang, Jianling
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
biliary excretion
hepatobiliary disposition
drug interactions
in vitro-in vivo correlations (IVIVC)
hepatic clearance
permeability
transporters
hepatocytes
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