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Synthesis and antiviral activity of 2 '-deoxy-6 '-substituted carbocyclic nucleosides
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2021, 页码: 12
作者:
Xue, Haitao
;
Guo, Shuang
;
Hu, Tianwen
;
Wei, Daibao
;
Xie, Yuanchao
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/01/18
2 '-deoxy carbocyclic nucleoside
antiviral activity
hepatitis B virus
Mitsunobu reaction
Cost-effective purification process development for chimeric hepatitis B core (HBc) virus-like particles assisted by molecular dynamic simulation
期刊论文
ENGINEERING IN LIFE SCIENCES, 2021, 页码: 15
作者:
Zhang, Bingyang
;
Yin, Shuang
;
Wang, Yingli
;
Su, Zhiguo
;
Bi, Jingxiu
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  |  
浏览/下载:53/0
  |  
提交时间:2021/08/31
hepatitis B core
molecular dynamic simulation
protein characterization
protein purification
virus‐
like particle
Performance of agarose and gigaporous chromatographic media as function of pore-to-adsorbate size ratio over wide span from ovalbumin to virus like particles
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2021, 卷号: 1638, 页码: 12
作者:
Yang, Yanli
;
Yu, Mengran
;
Ma, Guanghui
;
Su, Zhiguo
;
Zhang, Songping
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  |  
浏览/下载:54/0
  |  
提交时间:2021/03/29
Pore size
Protein size
Ion-exchange media
Ratio of pore-to-adsorbate size
Adsorption capacity
Adsorption kinetics
In vitro preparation of uniform and nucleic acid free hepatitis B core particles through an optimized disassembly-purification-reassembly process
期刊论文
PROTEIN EXPRESSION AND PURIFICATION, 2021, 卷号: 178, 页码: 7
作者:
Zhang, Yao
;
Liu, Yongdong
;
Zhang, Bingyang
;
Yin, Shuang
;
Li, Xiunan
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/08/31
Hepatitis B core (HBc)
Uniform VLPs
Nucleic acid removal
Disassembly-purification-reassembly
慢性乙型肝炎患者肠道菌群与肝脏生化指标的相关性
期刊论文
生物工程学报, 2021, 卷号: 37, 期号: 1, 页码: 301-311
作者:
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  |  
浏览/下载:43/0
  |  
提交时间:2021/12/01
慢性乙型肝炎
肠道菌群
肝脏生化指标
A biomimetic VLP influenza vaccine with interior NP/exterior M2e antigens constructed through a temperature shift-based encapsulation strategy
期刊论文
VACCINE, 2020, 卷号: 38, 期号: 38, 页码: 5987-5996
作者:
Wei, Jiangxue
;
Li, Zhengjun
;
Yang, Yanli
;
Ma, Xiaowei
;
An, Wenqi
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  |  
浏览/下载:39/0
  |  
提交时间:2020/10/30
Influenza Vaccine
Virus Like-particles
Biomimetic
Nucleoprotein
M2e
Discovery of Phthalazinone Derivatives as Novel Hepatitis B Virus Capsid Inhibitors
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 15, 页码: 8134-8145
作者:
Chen, Wuhong
;
Liu, Feifei
;
Zhao, Qiliang
;
Ma, Xinna
;
Lu, Dong
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  |  
浏览/下载:34/0
  |  
提交时间:2020/12/24
Repurposing of Kinase Inhibitors for Treatment of COVID-19
期刊论文
PHARMACEUTICAL RESEARCH, 2020, 卷号: 37
作者:
Weisberg, Ellen
;
Parent, Alexander
;
Yang, Priscilla L.
;
Sattler, Martin
;
Liu, Qingsong
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  |  
浏览/下载:33/0
  |  
提交时间:2020/10/26
Coronavirus
SARS-CoV-2
SARS-CoV
MERS-CoV
kinase inhibitors
pharmacokinetics
antiviral therapy
COVID-19
Cytosolic delivery of HBsAg and enhanced cellular immunity by pH-responsive liposome
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2020, 卷号: 324, 页码: 460-470
作者:
Hu, Fumin
;
Yue, Hua
;
Lu, Ting
;
Ma, Guanghui
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/09/22
pH-responsive
Membrane fusion
HBsAg
CTLs
Vaccine delivery
A novel rapid modularized hepatitis B core virus-like particle-based platform for personalized cancer vaccine preparation via fixed-point coupling
期刊论文
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2020, 卷号: 28, 页码: 13
作者:
Ji, Mei
;
Zhu, Jie
;
Xie, Xi-xiu
;
Liu, Dong-qun
;
Wang, Bin
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/10/30
Hepatitis b Core Protein
Virus-like Particle (Vlp)
Personalized Cancer Vaccine
Spycatcher/spytag
t Cell Epitope
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