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上海药物研究所 [10]
中国科学院大学 [2]
厦门大学 [1]
山东大学 [1]
山东师范大学 [1]
合肥物质科学研究院 [1]
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期刊论文 [16]
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2019 [1]
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2012 [2]
2011 [2]
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Induction of Cytochrome P450 Involved in the Accelerated Blood Clearance Phenomenon Induced by PEGylated Liposomes In Vivo
期刊论文
DRUG METABOLISM AND DISPOSITION, 2019, 卷号: 47, 期号: 4, 页码: 364-376
作者:
Wang, Fengling
;
Wu, Yifan
;
Zhang, Jiwen
;
Wang, Huihui
;
Xie, Xiaoting
收藏
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浏览/下载:2/0
  |  
提交时间:2020/07/01
Effects of diammonium glycyrrhizinate on hepatic and intestinal UDP-Glucuronosyltransferases in rats: Implication in herb-drug interactions
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2016, 卷号: 14
-
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  |  
浏览/下载:3/0
  |  
提交时间:2020/10/26
MYCOPHENOLATE-MOFETIL
GLYCYRRHETINIC ACID
LIVER-MICROSOMES
LICORICE
PATHWAY
PHARMACOKINETICS
MEDICINE
KAMPO
HPLC
3A
Diammonium glycyrrhizinate
UDP-glucuronosyltransferase
Sprague-Dawley rat
Drug-drug interaction
Diastereoisomer-specific effects of hexabromocyclododecanes on hepatic aryl hydrocarbon receptors and cytochrome p450s in zebrafish (danio rerio)
期刊论文
Chemosphere, 2015, 卷号: 132, 页码: 24-31
作者:
Du, Miaomiao
;
Fang, Chao
;
Qiu, Ling
;
Bong, Sijun
;
Zhang, Xian
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/05/10
Hexabromocyclododecane
Diastereoisomer
Aryl hydrocarbon receptor
Cytochrome p450
Role of hepatic cytochrome P450 enzymes in the detoxication of aristolochic acid I; effects on DNA adduct, mutation, and tumor formation
期刊论文
Genes and environment : the official journal of the Japanese Environmental Mutagen Society, 2015, 卷号: 37, 页码: 11
作者:
Luan, Yang
;
Xing, Guozhen
;
Ren, Jin
;
Gu, Jun
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  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Hepatic cytochrome P450s play a major role in monocrotaline-induced renal toxicity in mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 2, 页码: 292-300
作者:
Yao, Jun
;
Li, Cheng-gang
;
Gong, Li-kun
;
Feng, Chen-chen
;
Li, Chun-zhu
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  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
monocrotaline
pyrrolizidine alkaloid
hepatic cytochrome P450s
ketoconazole
metabolic activation
hepatic toxicity
renal toxicity
hepaticcytochromep450splayamajorroleinmonocrotalineinducedrenaltoxicityinmice
期刊论文
actapharmacologicasinica, 2014, 卷号: 35, 期号: 2, 页码: 292
作者:
Yao Jun
;
Li Chenggang
;
Gong Likun
;
Feng Chenchen
;
Li Chunzhu
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2020/07/01
monocrotaline
pyrrolizidine alkaloid
hepatic cytochrome P450s
ketoconazole
metabolic activation
hepatic toxicity
renal toxicity
Hepatic cytochrome P450s play a major role in monocrotaline-induced renal toxicity in mice.
期刊论文
Acta pharmacologica Sinica, 2014, 页码: 292
作者:
Yao Jun
;
Li Chenggang
;
Gong Likun
;
Feng Chenchen
;
Li Chunzhu
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/12/24
H-1 NMR-based metabolomic analysis of triptolide-induced toxicity in liver-specific cytochrome P450 reductase knockout mice
期刊论文
2012
Liu, Xia
;
Xue, Xiang
;
Gong, Likun
;
Qi, Xinming
;
Wu, Yuanfeng
;
Xing, Guozhen
;
Luan, Yang
;
Xiao, Ying
;
Wu, Xiongfei
;
Li, Yan
;
Chen, Min
;
Miao, Lingling
;
Yao, Jun
;
Gu, Jun
;
Lin, Donghai
;
Ren, Jin
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2013/01/14
Metabolomics
Triptolide
Toxicity
Cytochrome P450
Hepatotoxicity
H-1 NMR-based metabolomic analysis of triptolide-induced toxicity in liver-specific cytochrome P450 reductase knockout mice
期刊论文
METABOLOMICS, 2012, 卷号: 8, 期号: 5, 页码: 907-918
作者:
Liu, Xia
;
Xue, Xiang
;
Gong, Likun
;
Qi, Xinming
;
Wu, Yuanfeng
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Metabolomics
Triptolide
Toxicity
Cytochrome P450
Hepatotoxicity
Critical Role of Organic Anion Transporters 1 and 3 in Kidney Accumulation and Toxicity of Aristolochic Acid I
期刊论文
MOLECULAR PHARMACEUTICS, 2011, 卷号: 8, 期号: 6, 页码: 2183-2192
作者:
Xue, Xiang
;
Gong, Li-Kun
;
Maeda, Kazuya
;
Luan, Yang
;
Qi, Xin-Ming
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
organic anion transporter
aristolochic acid nephropathy
kidney toxicity
Oat1 and 3 knockout mice
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