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Fuzuloparib Maintenance Therapy in Patients With Platinum-Sensitive, Recurrent Ovarian Carcinoma (FZOCUS-2): A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase III Trial
期刊论文
JOURNAL OF CLINICAL ONCOLOGY, 2022, 卷号: 40
作者:
Li, Ning
;
Zhang, Youzhong
;
Wang, Jing
;
Zhu, Jianqing
;
Wang, Li
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/12/22
Pamiparib Monotherapy for Patients with Germline BRCA1/2-Mutated Ovarian Cancer Previously Treated with at Least Two Lines of Chemotherapy: A Multicenter, Open-Label, Phase II Study
期刊论文
CLINICAL CANCER RESEARCH, 2022, 卷号: 28
作者:
Wu, Xiaohua
;
Zhu, Jianqing
;
Wang, Jing
;
Lin, Zhongqiu
;
Yin, Rutie
收藏
  |  
浏览/下载:102/0
  |  
提交时间:2022/03/28
High chromosome instability identified by low-pass whole-genome sequencing assay is associated with TP53 copy loss and worse prognosis in BRCA1 germline mutation breast cancer
期刊论文
BREAST CANCER, 2021
作者:
Zhu, Liang
;
Pan, Jia-Ni
;
Qian, Ziliang
;
Ye, Wei-Wu
;
Wang, Xiao-Jia
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/09/06
CIN
TP53
BRCA1
LPWGS
Breast cancer
Multiple Endocrine Neoplasia Type 2B Associated Mixed Medullary and Follicular Thyroid Carcinoma in A Chinese Patient with RET M918T Germline Mutation
期刊论文
ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS, 2021, 卷号: 21
作者:
Qi, Xiao-Ping
;
Lin, Guo-Bing
;
Chen, Bo
;
Li, Feng
;
Cao, Zhi-Lie
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2021/04/26
Thyroid neoplasm
medullary thyroid carcinoma
mixed medullary-follicular carcinoma
multiple endocrine neoplasia type 2B
RET proto-oncogene
M918T mutation
Phase I dose-escalation and expansion study of PARP inhibitor, fluzoparib (SHR3162), in patients with advanced solid tumors
期刊论文
CHINESE JOURNAL OF CANCER RESEARCH, 2020, 卷号: 32, 期号: 3, 页码: 370-+
作者:
Li, Huiping
;
Liu, Rongrui
;
Shao, Bin
;
Ran, Ran
;
Song, Guohong
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/24
Phase I
PARP inhibitor (fluzoparib)
solid tumor
pharmacokinetics
safety
antitumor activity
Exploration of Genetic Variations through Single-cell Whole-genome Sequencing in the Model Ciliate Tetrahymena thermophila
期刊论文
JOURNAL OF EUKARYOTIC MICROBIOLOGY, 2019, 期号: 1, 页码: 12
作者:
Chen, Kai
;
Wang, Guangying
;
Xiong, Jie
;
Jiang, Chuanqi
;
Miao, Wei
收藏
  |  
浏览/下载:146/0
  |  
提交时间:2019/08/19
Ciliated protozoa
population genetics
single-cell resequencing
variation detection
whole-genome amplification
Identification of the Germline Mutation Profile in Esophageal Squamous Cell Carcinoma by Whole Exome Sequencing
期刊论文
FRONTIERS IN GENETICS, 2019, 卷号: 10
作者:
Deng, Jiaying
;
Wang, Xiaoling
;
Ye, Junyi
;
Zhou, Daizhan
;
Liu, Yun
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/12/05
whole exome sequencing
ESCC
germline mutation
VUS
clinical features
Multiple cancer susceptible genes sequencing in BRCA-negative breast cancers with high hereditary risk
会议论文
作者:
Lang, G-T
;
Hu, X.
;
Shao, Z-M
;
Huang, W.
;
Shi, J-X
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/05
germline mutation
BRCA-negative
hereditary breast cancer
multiple-gene sequencing
Germline DNA Repair Gene Mutation Landscape in Chinese Prostate Cancer Patients
期刊论文
EUROPEAN UROLOGY, 2019, 卷号: 76, 期号: 3
作者:
Wei, Yu
;
Wu, Junlong
;
Gu, Weijie
;
Qin, Xiaojian
;
Dai, Bo
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/12/05
Germline mutation
DNA repair genes
Chinese population
Prostate cancer
Germline and somatic mutations of multi-gene panel in Chinese patients with epithelial ovarian cancer: a prospective cohort study
期刊论文
2019, 卷号: 12, 期号: 1, 页码: 80
作者:
Li Wenhui
;
Shao Di
;
Li Lei
;
Wu Ming
;
Ma Shuiqing
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/01/03
Epithelial ovarian cancer
Germline mutation
Homologous recombination deficiency
Next-generation sequencing
Somatic mutation
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